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Scholars @ Weill Cornell Medicine

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Scholars8,800 Publications201,348 Funding7,267 Clinical research69

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Scholars8,800 Publications201,348 Funding7,267 Clinical research69

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Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional58
Observational11

Phase

Not applicable49
Not reported11
Phase 23
Phase 33
Phase 42
Phase 2/31

Investigator

Brian DeRubertis5
Joan Stilling4
Abhishek Jaywant3
Conor Liston3
David M. Otterburn3

Department

Medicine26
Surgery17
Psychiatry8
Cardiothoracic Surgery4
Neurological Surgery4

Condition

Stroke6
Atrial Fibrillation5
Ischemic Stroke5
Heart Failure4
Cardiovascular Diseases3

Intervention type

Device69
Drug197
Procedure58
Other57
Biological49
Behavioral38

Sponsor type

Industry45
WCM (investigator-initiated)18
Other academic6

Start date

Recruiting×Device×Clear all

Showing 1–20 of 69 studiesSort:

RecruitingInterventional · Not applicableNCT02235857 ↗
Treatment of Drug-resistant Pediatric Primary Focal Segmental Glomerulosclerosis Using the Liposorber® LA-15 System

FiltersClear all

Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional58
Observational11

Phase

Not applicable49
Not reported11
Phase 23
Phase 33
Phase 42
Phase 2/31

Investigator

Brian DeRubertis5
Joan Stilling4
Abhishek Jaywant3
Conor Liston3
David M. Otterburn3

Department

Medicine26
Surgery17
Psychiatry8
Cardiothoracic Surgery4
Neurological Surgery4

Condition

Stroke6
Atrial Fibrillation5
Ischemic Stroke5
Heart Failure4
Cardiovascular Diseases3

Intervention type

Device69
Drug197
Procedure58
Other57
Biological49
Behavioral38

Sponsor type

Industry45
WCM (investigator-initiated)18
Other academic6

Start date

Recruiting×Device×Clear all

Showing 1–20 of 69 studiesSort:

RecruitingInterventional · Not applicableNCT02235857 ↗
Treatment of Drug-resistant Pediatric Primary Focal Segmental Glomerulosclerosis Using the Liposorber® LA-15 System

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Jim W. Cheung3
James E. Ip3
Manish Ashwin Parikh3
Michael G Kaplitt3
Reem Z. Sharaiha3
Shmuel Chen3
Jaikirshan Khatri2
Rajesh Kumar Malik2
Seth H. Goldbarg2
Anna Podolanczuk1
Anthony O. Ahmed1
Cheguevara Afaneh1
Christopher F Liu1
Christopher Lau1
Darshana M Dadhania1
Gunisha Kaur1
Harsimran Singh1
Harini Sarva1
Hooman Kamel1
Evelyn M. Horn1
Immanuel Elbau1
Jared Knopman1
Joonhyuk Kim1
Juan Pablo Rocca1
Juan M. Pascual1
Lea Channah Lowenfeld1
Eilon Ram1
Larissa Rodriguez1
Mehraneh Dorna Jafari1
Mario Fl Gaudino1
Yoshifumi Naka1
Parag Goyal1
Paul Chapman1
Rasa Zarnegar1
Robert J. Winchell1
Benjamin Samstein1
Shari Lipner1
Uqba Khan1

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Rehabilitation Medicine4
Neurology2
Anesthesiology1
Dermatology1
Pediatrics1
Urology1

Show all 50

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Chronic Limb-Threatening Ischemia3
Depressive Disorder, Treatment-Resistant3
Anxiety Disorders2
Atrioventricular Block2
Coronary Artery Disease2
Depression2
Depressive Disorder, Major2
Obesity2
Tricuspid Valve Insufficiency2
Alzheimer Disease1
Aneurysm1
Aneurysm, Aortic Arch1
Angina Pectoris1
Aortic Valve Insufficiency1
Aortic Valve Stenosis1
Arrhythmias, Cardiac1
Bipolar Disorder1
Bites and Stings1
Bradycardia1
Breast Neoplasms1
Carcinoma, Hepatocellular1
Carcinoma, Non-Small-Cell Lung1
Cognitive Dysfunction1
Colonic Neoplasms1
Colorectal Neoplasms1
Diabetes Mellitus, Type 21
Dissection, Thoracic Aorta1
Epilepsy1
Essential Hypertension1
Fatigue1
Foramen Ovale, Patent1
Gastric Outlet Obstruction1
Glomerulosclerosis, Focal Segmental1
Glucose Metabolism Disorders1
Glut1 Deficiency Syndrome1
Glycogen Storage Disease Id1
Heart Diseases1
Heart Failure, Diastolic1
Hemorrhagic Stroke1
Hernia, Hiatal1
Hypertension1
Hypertension, Pregnancy-Induced1
Hypertension, Pulmonary1
Infections1
Inflammation1

Intervention: Device: LIPOSORBER® LA-15 System
Dates: May 2015 – Sep 2027 (est.)
Sponsor: Kaneka Pharma America Corporation

Focal Segmental Glomerulosclerosis

RecruitingInterventional · Not applicableNCT03671889 ↗

Assessment of Safety and Efficacy of ExAblate Blood-Brain Barrier Disruption for the Treatment of Patients With Probable Alzheimer's Disease

Michael G KaplittPI

Intervention: Device: Blood Brain Barrier (BBB) Disruption
Dates: Sep 2018 – Jan 2028 (est.)
Sponsor: InSightec

Alzheimer Disease

RecruitingInterventional · Phase 3NCT04041479 ↗

Efficacy of Biomarker-guided rTMS for Treatment Resistant Depression

Conor ListonPI

Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Dates: Sep 2021 – Apr 2027 (est.)
Sponsor: Weill Medical College of Cornell University

Treatment Resistant DepressionMajor Depressive Disorder

RecruitingInterventional · Not applicableNCT04097145 ↗

A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Tricuspid Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System and Optimal Medical Therapy (OMT) Compared to OMT Alone in Patients With Tricuspid Regurgitation

Shmuel ChenPI

Intervention: Device: Edwards PASCAL System · Drug: Optimal Medical Therapy
Dates: Dec 2019 – Dec 2027 (est.)
Sponsor: Edwards Lifesciences Corp.

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease

RecruitingInterventional · Not applicableNCT04101669 ↗

A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the RESET® System for Glycemic Improvement in Patients With Inadequately Controlled Type 2 Diabetes and Obesity

Reem Z. SharaihaPI

Intervention: Device: RESET Liner · Other: Sham
Dates: Sep 2019 – Dec 2027 (est.)
Sponsor: GI Dynamics, Inc.

Diabetes type2Obesity

RecruitingInterventional · Not applicableNCT04197921 ↗

A Feasibility Clinical Trial of Exablate for Low Intensity Focused Ultrasound Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Abuse Disorders (SUDs)

Michael G KaplittPI

Intervention: Device: Exablate Model 4000 Type 2.0/2.1
Dates: Nov 2019 – Dec 2026 (est.)
Sponsor: InSightec

Opioid-use DisorderSubstance Use Disorders

RecruitingInterventional · Not applicableNCT04339699 ↗

STITCH - Prospective Multi Center Comparative Parallel Concurrent Study of the NobleStitch EL Compared to FDA Approved Amplatzer Occluder Device for Closure of Patent Foramen Ovale to Prevent Recurrent Ischemic Stroke

Harsimran SinghPI

Intervention: Device: NobleStitch™EL Suture Mediated Closure System · Device: Amplatzer PFO Occluder
Dates: Jan 2021 – Dec 2026 (est.)
Sponsor: Nobles Medical Technologies II, Inc.

Foramen Ovale, PatentStroke, Ischemic

RecruitingInterventional · Not applicableNCT04555161 ↗

An Early Feasibility Study Assessing Treatment of Pulmonary Hypertension Using the Aria CV Pulmonary Hypertension System

Evelyn M. HornPI

Intervention: Device: Aria CV Pulmonary Hypertension System
Dates: Mar 2021 – Oct 2025 (est.)
Sponsor: Aria CV, Inc.

Pulmonary Arterial HypertensionPulmonary HypertensionRight Heart Dysfunction

RecruitingInterventional · Not applicableNCT04592445 ↗

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction: Randomized Controlled Feasibility Trial - The Rebalance HF Study

Parag GoyalPI

Intervention: Device: Greater Splanchnic Nerve Ablation · Device: Sham Control
Dates: Dec 2020 – Jan 2028 (est.)
Sponsor: Axon Therapies, Inc

Heart Failure With Preserved Ejection Fraction (HFpEF

RecruitingObservationalNCT04674969 ↗

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature (ELEGANCE)

Brian DeRubertisPI

Intervention: Device: Any eligible commercially available Boston Scientific Corporation (BSC) drug-eluting device.
Dates: Mar 2021 – Jan 2028 (est.)
Sponsor: Boston Scientific Corporation

Peripheral Vascular Diseases

RecruitingInterventional · Not applicableNCT04891510 ↗

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

David M. OtterburnPI

Intervention: Device: REVOLVE Advanced Adipose System · Device: LipoGrafter · Procedure: Viality
Dates: May 2021 – Jun 2028 (est.)
Sponsor: Weill Medical College of Cornell University

MastectomyMammaplastyBreast Reconstruction

RecruitingObservationalNCT04991831 ↗

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Michael G KaplittPI

Intervention: Device: Unilateral thalamotomy
Dates: Apr 2022 – Dec 2027 (est.)
Sponsor: InSightec

Tremor Associated With Tremor Dominant Parkinson's Disease

RecruitingInterventional · Not applicableNCT05064709 ↗

Assessment of Implantable CCM in the Heart Failure Group With Higher Ejection Fraction

James E. IpPI

Intervention: Device: Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System · Device: OPTIMIZER™ Smart Mini System
Dates: Feb 2022 – Feb 2029 (est.)
Sponsor: Impulse Dynamics USA, Inc.

Heart FailureHeart Failure With Preserved Ejection FractionHeart Failure With Mid Range Ejection Fraction+2 more

RecruitingObservationalNCT05085704 ↗

Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease

Juan M. PascualPI

Intervention: Device: Magnetic resonance imaging
Dates: May 2022 – Jun 2029 (est.)
Sponsor: Weill Medical College of Cornell University

Glut1 Deficiency Syndrome 1Glucose Metabolism DisordersEpilepsy+4 more

RecruitingInterventional · Not applicableNCT05102019 ↗

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Jaikirshan KhatriPI

Intervention: Device: Arm 1: treatment with Shockwave Reducer · Other: Arm 2 (control): Implantation procedure with no device implanted · Device: Arm 3 (unblinded, non-randomized): Single arm registry
Dates: Jan 2022 – Jul 2027 (est.)
Sponsor: Shockwave Medical INC

Refractory Angina

RecruitingInterventional · Not applicableNCT05172973 ↗

Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Shmuel ChenPI

Intervention: Device: SAPIEN X4/X4S THV
Dates: Nov 2023 – Mar 2029 (est.)
Sponsor: Edwards Lifesciences Corp.

Aortic Valve InsufficiencyAortic Valve Stenosis

RecruitingInterventional · Phase 2/3NCT05174169 ↗

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Uqba KhanPI

Intervention: Device: Signatera test · Drug: mFOLFOX6 3-6 month · Drug: CAPOX 3 month · Drug: mFOLFIRINOX · Drug: mFOLFOX6 6 month · Drug: CAPOX 6 month
Dates: Jul 2022 – Mar 2029 (est.)
Sponsor: NRG Oncology

Stage III Colon Cancer

RecruitingInterventional · Not applicableNCT05190978 ↗

Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

David M. OtterburnPI

Intervention: Device: Acellular Dermal Matrix · Procedure: Reconstruction without ADM
Dates: Oct 2022 – Apr 2027 (est.)
Sponsor: University of California, Los Angeles

Breast CancerBreast ImplantComplications, Infection or Inflammation

RecruitingObservationalNCT05301140 ↗

Vivistim Registry for Paired VNS Therapy (GRASP)

Joan StillingPI

Intervention: Device: Vivistim System
Dates: Mar 2023 – Dec 2028 (est.)
Sponsor: Microtransponder

Upper Extremity Problem

RecruitingInterventional · Not applicableNCT05313165 ↗

Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia: The PROMISE III Trial

Brian DeRubertisPI

Intervention: Device: LimFlow Stent Graft System
Dates: Dec 2022 – May 2027 (est.)
Sponsor: LimFlow, Inc.

Critical Limb IschemiaChronic Limb-Threatening IschemiaPeripheral Arterial Disease

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