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Highlights

  1. 1
    Nature · 2024
    PMID: 39232159PMCID: PMC11410656DOISenior author256 citations
  2. 2
    Nature neuroscience · 2023
    PMID: 36894656PMCID: PMC11446249DOISenior author138 citations
  3. 3
    Cell · 2021
    PMID: 33861951PMCID: PMC8684294DOISenior author88 citations

Publications

139 publications

Active

18 grants
  • KP
    2026 NARSAD Young Investigator Grant
    Brain & Behavior Research Foundation · 2027–2029
    35101
  • MPI
    Neuromodulatory control of prefrontal circuit function and reward-seeking
    National Institute of Mental Health · 2018–2028· 2 renewals
    R01MH118451-08
  • Co-I
    AR² - Autism Replication, Validation, and Reproducibility Center
    Office of the Director, NIH · 2025–2028
    OT2OD040511-01
  • PI
    An open-label trial of a novel prefrontal cortical interneuron-targeting antidepressant medication combination to achieve rapid antidepressant responses with minimal side effects
    Hope for Depression Research Foundation · 2026–2028
    HDRF 262807-01
  • Co-I
    Target Engagement During Social Reward Psychotherapy for Mid- and Late-Life Suicidality: A Precision Imaging Trial
    National Institute of Mental Health · 2023–2028
    R01MH133953-01
  • Sub-PI
    Global Deep Learning Initiative to Understand Outcomes in Major Depression
    National Institute of Mental Health · 2023–2028 · via University of Southern California
    R01MH131806-04
  • KP
    Closing the Interspecies Gap: Breakthrough Methods for Comparative Molecular Neurodynamics
    Burroughs Wellcome Fund · 2024–2027
    BWF 240354-01
  • Co-I
    Scalable Biomarkers and Generative Digital Twins for Personalized Neurostimulation in Depression
    National Institute of Mental Health · 2022–2027
    R01MH131534-01
  • Co-I
    Photopharmacological interrogation of presynaptic neuromodulation of cortico-amygdalar circuits
    National Institute of Mental Health · 2022–2027
    R01MH129693-01
  • Sub-PI
    Maintenance rTMS for depression (Maitr-De)
    National Institute of Mental Health · 2025–2027 · via University of California, San Diego
    R61MH138647-02
  • MPI
    Efficacy of biomarker-guided rTMS for treatment resistant depression, Data Sharing Agreement
    National Institute of Mental Health · 2019–2027
    R01MH118388-05
  • Co-I
    Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memories
    National Institute on Drug Abuse · 2022–2027 · via Temple University· 2 renewals
    R01DA053261-03
  • KP
    Microbial Regulation of Microglial Function
    National Institute of Mental Health · 2022–2026Career
    K08MH130773-04
  • MPI
    Biomarker-Guided Antidepressant Selection for Treatment-Resistant Depression
    National Institute of Mental Health · 2024–2026
    UG3MH137656-01
  • PI
    Longitudinal Studies of Synaptic Remodeling as a Therapeutic Target in Depression (Renewal)
    Hope for Depression Research Foundation · 2023–2026
    HDRF 231267-02
  • Co-I
    Remote computational phenotyping of behavioral and affective dynamics in major depression
    National Institute of Mental Health · 2020–2026 · via Yale University
    R01MH124110-03
  • Co-I
    Genetically-Targeted Photo-Pharmacology for Native Opioid Receptors
    National Institute on Drug Abuse · 2020–2026
    R61DA051529-01
  • MPI
    Impact of BDNF on the Development of Social Behavior Circuits
    National Institute of Mental Health · 2020–2026
    R01MH123154-05
Completed grants (40)
  • Sub-PI
    Modeling and Model Integration (Transition Funding)
    Wellcome Leap, Inc. · 2024–2025 · via Vanderbilt University
    UNIV61176
  • Co-I
    Brain-based Mechanisms of Emotion Regulation in Aging and Mood Disorders
    National Institute of Mental Health · 2020–2025 · via The Brigham & Women's Hospital INC
    R01MH124381-04
  • KP
    Endogenous and causal roles of VTA and LC dopaminergic projections in contextual learning and behavior
    Whitehall Foundation, Inc. · 2021–2025
    WF 2021-08-089
  • PI
    Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD
    New Venture Fund · 2020–2025
    NVF 202423-05
  • KP
    Implications of Prefrontal Cortex Development for Adolescent Reward Seeking Behavior
    National Institute of Mental Health · 2023–2025
    K99MH132082-01A1
  • Sub-PI
    Light activated drugs for in vivo photopharmacology
    National Institute of Neurological Disorders and Stroke · 2022–2025 · via University of California, San Diego
    RF1NS126073-01
  • KP
    7T Magnetic Resonance Imaging System for Basic, Translational and Clinical Research
    Office of the Director, NIH · 2021–2025
    S10OD027039-01A1
  • Co-I
    Molecular and circuit defects underlying different SCN2A mutations and ASDs
    National Institute of Mental Health · 2019–2025
    R01MH118934-06A1
  • Sub-PI
    The Effects of Stanford Accelerated Intelligent Neuromodulation Therapy on Explicit and Implicit Suicidal Cognition
    National Institute of Mental Health · 2023–2025 · via Magnus Medical, Inc.
    R01MH125160-03
  • PI
    WELLCOME LEAP MARFA Master Contract - Personalized Therapeutic Neuromodulation for Anhedonic Depression
    Wellcome Leap, Inc. · 2021–2024
    WLI 220839-02
  • KP
    Corticostriatal and Corticoinsular Circuit Mechanisms Underlying Stress Effects on Effort-based Reward Processing
    National Institute of Mental Health · 2021–2024Career
    K99MH127291-02
  • PI
    Two-photon laser-scanning microscope for interdisciplinary collaborations at Weill Cornell
    Office of the Director, NIH · 2022–2024
    S10OD032415-01
  • PI
    Diagnostic and prognostic biomarkers for subtypes of addiction-related circuit dysfunction
    National Institute on Drug Abuse · 2019–2024· 2 renewals
    R01DA047851-04
  • KP
    Encoding of fear and safety discrimination in prefrontal-amygdala projections
    National Institute of Mental Health · 2021–2023Career
    K08MH127383-01
  • KP
    Effects of early life stress on functional development of prefrontal-amygdala connectivity
    National Institute of Mental Health · 2020–2023
    K00MH124183-02
  • PI
    Longitudinal Studies of Synaptic Remodeling as a Therapeutic Target in Depression (Year 2 Renewal)
    Hope for Depression Research Foundation · 2020–2023
    HDRF 203840-03
  • KP
    DNA methylation based binary enhancers govern neuronal allocation to coding in the hippocampus
    National Institute of Neurological Disorders and Stroke · 2018–2023
    R01NS106056-01A1
  • PI
    Addgene 699905
    Addgene, Inc. · 2022–2023
    Addgene 699905
  • MPI
    Dissection Of The Role Of Serotonin Circuits In Reward And Aversion
    National Institute of Mental Health · 2021–2023Career
    K08MH113039-05
  • KP
    Investigate for the Effect of Mitochondrial Oxidative Stress on Prefrontal Circuit and Anhedonic Behavioral Change in Depression
    Brain & Behavior Research Foundation · 2020–2023
    BBRF 28470
  • PI
    Prefrontal Cortical Circuit Mechanisms of Working Memory
    Rita Allen Foundation · 2017–2022
    RAF 17070977-01
  • KP
    Targeting salience network dysfunction in depression with individualized brain network mapping and TMS
    National Institute of Mental Health · 2019–2022
    F32MH120989-01
  • Co-I
    ApoE4 and Mechanisms of Diffuse White Matter Injury
    National Institute of Neurological Disorders and Stroke · 2016–2022
    R01NS100447-01
  • PI
    Prefrontal Cortical Microcircuit Mechanisms of Working Memory Deficits in Chronic Stress
    National Institute of Mental Health · 2016–2022· 2 renewals
    R01MH109685-05
  • KP
    Prefrontal circuit mechanisms underlying antidepressant effects of sleep deprivation: a role for metabotropic glutamate receptors
    National Institute of Mental Health · 2019–2022
    F32MH117973-01A1
  • KP
    Prefrontal Somatostatin-Expressing Interneurons in Action Valuation Processing and Motivational Anhedonia
    National Institute of Mental Health · 2017–2021Fellowship
    F30MH115622-02
  • KP
    Prefrontal Microcircuits Underlying Cognitive Flexibility (K99 Administrative Supplement)
    National Institute of Mental Health · 2018–2021· 2 renewals
    K99MH117271-02S1
  • Co-I
    Dietary Sodium, Neurovascular Dysfunction and Cerebrovascular Risk
    National Institute of Neurological Disorders and Stroke · 2015–2021
    R01NS095441-03
  • KP
    Prefrontal Circuits Underlying Attention Selection
    Brain & Behavior Research Foundation · 2018–2021
    BRF 17091388-01
  • KP
    Prefrontal Microcircuit Mechanisms Underlying Extinction Memory Formation
    National Institute of Mental Health · 2017–2020Fellowship
    F32MH115654-01
  • PI
    How Stress-Induced Synaptic Remodeling in Specific PFC Circuits Impacts Depression-Like Behaviors
    Hope for Depression Research Foundation · 2019–2020
    HDRF 200192-01
  • PI
    Diagnostic Neuroimaging Biomarkers of Dysfunctional Valence Systems in Depression and Anxiety
    National Institute of Mental Health · 2018–2019
    R56MH114976-01A1
  • KP
    The cellular memory of early life adversity
    National Institute of Mental Health · 2018–2019
    R56MH117004-01
  • PI
    Prefrontal Cortical Circuit Mechanisms of Working Memory
    Esther A. & Joseph Klingenstein Fund, Inc. · 2016–2019Fellowship
    KSF 170910-03
  • KP
    Exploring the Regulation and Function of Gap Junction-Mediated Signaling in Glioblastoma Multiforme
    National Cancer Institute · 2017–2019Fellowship
    F32CA217048-02
  • PI
    Circuit Biomarkers for Diagnosis and Treating Neurophysiological Subtypes of Depression
    International Mental Health Research Organization · 2015–2018
    IMHRO 16060875-03
  • PI
    Neuroimaging and related data from UK Biobank
    UK Biobank · 2017–2018
    MTA 180131-01
  • PI
    Developing Neuroimaging Biomarkers and Mouse Models of Circuit Pathology in Autism Spectrum Disorder
    The Hartwell Foundation · 2015–2018
    THF 15030354-02
  • PI
    Chronic Stress Effects on Connectivity in a Limbic Circuit
    National Institute of Mental Health · 2014–2017
    R00MH097822-05
  • PI
    Chronic Stress Effects on Connectivity in a Limbic Circuit
    NIMH · 2012–2014 · via NIH RePORTER
    K99MH097822-02

Honors & distinctions

1 honor
  • Member · American Society for Clinical Investigation · 2020

Clinical research

9 studies

Active

7 studies
  • PI
    Biomarker-Guided Antidepressant Selection for Treatment-Resistant Depression
    PHASE4 · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
    Depression - Major Depressive Disorder; Treatment-resistant Depression (TRD); rTMS; Ketamine; fMRI
    NCT07680140
  • PI
    Precision Functional Mapping to Predict and Track ERP Response in Pediatric Obsessive-Compulsive Disorder: A Longitudinal fMRI Study
    NA · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
    Obsessive-Compulsive Disorder
    NCT07570108
  • PI
    Assessment of Brain Circuitry in Mental Health: A Longitudinal Neuroimaging Approach (ABC-MH)
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
  • PI
    Precision Functional Mapping in Pediatric Obsessive-Compulsive Disorder: A Longitudinal Dense-Sampling fMRI Study
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
  • PI
    Maintaining the Acute Therapeutic Effect of rTMS in Treatment-Resistant Depression (Maitr-De)
    NA · University of California, San Diego · OPEN TO ACCRUAL (as of 2025)
    Major Depressive Disorder; Treatment Resistant Depression
    NCT06938841
  • PI
    Efficacy of Biomarker-guided rTMS for Treatment Resistant Depression
    PHASE3 · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2021)
    Treatment Resistant Depression; Major Depressive Disorder
    NCT04041479
  • PI
    Accelerated TMS for Depression and OCD
    NA · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2021)
    Depression; OCD
    NCT04982757
Completed & closed trials (2)
  • PI
    A Multi-Site, Randomized, Double-Blind Trial Assessing The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition
    PHASE2; PHASE3 · Magnus Medical, Inc. · IRB STUDY CLOSURE (as of 2025)
    Major Depressive Disorder; Major Depressive Episode; Suicidal Ideation
    NCT03693105
  • PI
    Anonymous tracking of psychiatric symptoms and mental health care needs in health care workers during the COVID-19 pandemic
    Sackler Institute (Weill Cornell) · IRB STUDY CLOSURE (as of 2023)

Available technologies

News mentions

Show 13 more mentions
9 MD students · 14 PhD students · 3 MD-PhD students · 14 Postdocs

External relationships

Advisory/Scientific Board Member

Delix Therapeutics, Inc · Neuroscience Software, Inc.