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Highlights

  1. 1
    Transplantation · 2020
    PMID: 31343576PMCID: PMC6834867DOISenior author92 citations
  2. 2
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    PMID: 33043597PMCID: PMC7675359DOISenior author78 citations
  3. 3
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020
    PMID: 32678882PMCID: PMC7454827DOISenior author70 citations

Publications

152 publications

Active

6 grants
  • MPI
    Gut microbial beta-glucuronidases as a biomarker for mycophenolic acid enterohepatic recirculation and associated toxicities
    National Institute of Diabetes and Digestive and Kidney Diseases · 2026–2029 · via University of Pennsylvania
    R01DK139249-03
  • PI
    6/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center
    National Institute of Diabetes and Digestive and Kidney Diseases · 2017–2028· 2 renewals
    U01DK116100-07
  • Co-I
    Multianalyte Profiling of Kidney Allograft Recipients (Biopharma)
    CareDx, Inc. · 2020–2027BioPharma Alliance
    BP 204524-01
  • MPI
    Microbial Biomarkers for Diagnosing and Predicting Infections in Kidney Transplant Recipients
    National Institutes of Health · 2026–2027 · via University of Pennsylvania
    R01AI184528-03
  • Co-I
    Optimization of UroMap
    CareDx, Inc. · 2023–2027BioPharma Alliance
    BP 241334-01
  • MPI
    Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantation
    National Institute of Allergy and Infectious Diseases · 2020–2026 · via Cornell University - Ithaca
    R01AI151059-05
Completed grants (6)
  • Co-I
    Biomolecular Markers for Safe Minimization of Immunosuppression
    National Institute of Allergy and Infectious Diseases · 2009–2022· 3 renewals
    R37AI051652-15
  • PI
    Obese Living Kidney Donor
    The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham · 2018–2019Contract
    SA 184303-01
  • Co-I
    Validation of SHADE a Mobile Technology for Monitoring of Ultraviolet Exposure
    National Cancer Institute · 2017–2019 · via YouV Labs
    HHSN261201700005C
  • Co-I
    Single-Cell RNA Sequencing of Urinary Cells for the Deconvolution of Human Kidney Allograft Rejection
    Mendez National Institute of Transplantation Foundation, The · 2017–2018
    19
  • KP
    FoxP3 Regulatory Network mRNA Profiles and Human Renal Transplant Outcomes
    National Institute of Allergy and Infectious Diseases · 2007–2011
    R01AI072790-05EWO
  • MPI
    URINARY CELL MRNA PROFILES OF REJECTION
    NCRR · 2007–2007 · via NIH RePORTER
    M01RR000047-47

Clinical research

12 studies

Active

1 study
  • PI
    Treatment of Drug-resistant Pediatric Primary Focal Segmental Glomerulosclerosis Using the Liposorber® LA-15 System
    NA · Kaneka Pharma America Corporation · OPEN TO ACCRUAL (as of 2019)
    Focal Segmental Glomerulosclerosis
    NCT02235857
Completed & closed trials (11)
  • PI
    A Multicenter, Open-label Single Arm Study to Evaluate the Safety and Efficacy of Sparsentan in Posttransplant Immunoglobulin A Nephropathy (IgAN) or Focal Segmental Glomerulosclerosis (FSGS) (SPARX)
    PHASE4 · Travere Therapeutics INC · CLOSED TO ACCRUAL (as of 2026)
    Proteinuria; Immunoglobulin A (IgA) Nephropathy; Focal Segmental Glomerulosclerosis; Kidney Transplant
    NCT07219121
  • PI
    Impact of Covid-19 illness on kidney transplant candidates and recipients.
    Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2026)
  • PI
    Safety, Tolerability and Efficacy of AntiBKV as Treatment of BKV Infection in Kidney Transplant Recipients, a Randomized Phase II/III Study, Double-blind and Placebo-controlled
    PHASE2; PHASE3 · Memo Therapeutics AG · IRB STUDY CLOSURE (as of 2025)
    BK Viremia; BKV DNAemia
    NCT05769582
  • PI
    A 12-Month, Randomized, Open-Label, Phase IIA Study Evaluating the Safety and Efficacy of Siplizumab in Combination With Belatacept and MPA Compared to Standard of Care Immunosuppression in de Novo Renal Transplant Recipients (ASCEND)
    PHASE2 · ITB-MED LLC · IRB STUDY CLOSURE (as of 2025)
    Renal Transplantation
    NCT05669001
  • PI
    Biomarkers for Detecting and Predicting Infections in Transplant Recipients
    Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2025)
  • PI
    Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry
    CareDx, Inc. · IRB STUDY CLOSURE (as of 2025)
    Kidney Transplant Rejection
    NCT03326076
  • PI
    Metagenomic Profiling of Urinary Cell-free DNA to Monitor UTI after Kidney Transplantation
    Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2025)
  • PI
    A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients
    PHASE3 · Vitaeris Inc. · IRB STUDY CLOSURE (as of 2024)
    Antibody-mediated Rejection
    NCT03744910
  • PI
    Global Registry for Long-Term Follow-up of Patients Participating in Clinical Trials with_x000D_ Posoleucel (ALVR105)
    AlloVir, Inc. · IRB STUDY CLOSURE (as of 2024)
  • PI
    Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled, Multiple Dosing Interval, 2-period Study of the Safety, Tolerability and Effectiveness of Adoptively Transferred Posoleuccel (ALVR105) Multivirus-specific T Cells in Kidney Transplant Recipients With Either High or Low Levels of BK Viremia
    PHASE2 · AlloVir, Inc. · IRB STUDY CLOSURE (as of 2023)
    BK Virus Nephropathy; BK Virus Infection
    NCT04605484
  • PI
    OUTCOMES OF KIDNEYCARE ON RENAL ALLOGRAFTS (OKRA)- sub-study of EVALUATION OF PATIENT OUTCOMES FROM THE KIDNEY ALLOGRAFT OUTCOMES ALLOSURE REGISTRY (KOAR)
    CareDx, Inc. · IRB STUDY CLOSURE (as of 2022)

News mentions

Mentoring

1 mentee
  • ST
    Stephanie Tsai
    MD mentee · Class of 2020

External relationships

Leadership Roles

American Society of Transplatation

Professional Services

NIH Center for Scientific Review · UpToDate, Inc.

Other

Memo Therapeutics AG