Shmuel Chen, MD, PhD

Highlights

1
European heart journal · 2020
SCShmuel Chen BRBjorn Redfors
PMID: 31711153PMCID: PMC8204653DOIFirst author57 citations
2
JACC. Cardiovascular interventions · 2024
SCShmuel Chen
PMID: 38866455DOIFirst author26 citations
3
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2020
SCShmuel Chen
PMID: 32649037PMCID: PMC8246818DOIFirst author38 citations

95

1

1 grant

Co-I
Right Heart Cardiac Magnetic Resonance Tissue Characterization for Clinical and Therapeutic Prognostication in Functional Tricuspid Regurgitation
National Heart, Lung, and Blood Institute · 2026–2031
R01HL183658-01A1

11

5 studies

PI
Incidence of HALT-HAM in Patients with Bicuspid versus Tricuspid Aortic Valves post-TAVR
Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
PI
Uncovering the Natural History of Mid-Ventricular/Sub-Valvular Pressure Gradients after TAVR
Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
PI
Early Feasibility Study (EFS) to Assess the Safety and Performance of the Innoventric Trillium™ Stent Graft in the Treatment of Severe or Greater Tricuspid Regurgitation (TR)
NA · Innoventric LTD · OPEN TO ACCRUAL (as of 2024)
Tricuspid Regurgitation; Tricuspid Regurgitation Functional
NCT06212193
PI
Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
NA · Edwards Lifesciences Corp. · OPEN TO ACCRUAL (as of 2023)
Aortic Valve Insufficiency; Aortic Valve Stenosis
NCT05172973
PI
A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Tricuspid Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System and Optimal Medical Therapy (OMT) Compared to OMT Alone in Patients With Tricuspid Regurgitation
NA · Edwards Lifesciences Corp. · OPEN TO ACCRUAL (as of 2021)
Tricuspid Regurgitation; Tricuspid Valve Insufficiency; Tricuspid Valve Disease
NCT04097145

Completed & closed trials (6)

PI
Cerebral Protection in Transcatheter Aortic Valve Replacement - The PROTEMBO C Trial
NA · Protembis GmbH · IRB STUDY CLOSURE (as of 2025)
Valvular Heart Disease
NCT04618718
PI
SAPIEN M3 System Transcatheter Mitral Valve Replacement Via Transseptal Access
NA · Edwards Lifesciences Corp. · CLOSED TO ACCRUAL (as of 2025)
Mitral Regurgitation; Mitral Valve Insufficiency
NCT04153292
PI
Single-Patient Emergent Use of an Investigational Product - JenaValve Trilogyâ ¢ Heart Valve System
Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2025)
PI
Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
NA · Edwards Lifesciences Corp. · CLOSED TO ACCRUAL (as of 2024)
Aortic Valve Insufficiency; Aortic Valve Stenosis
NCT05172973
PI
Edwards EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device
NA · Edwards Lifesciences Corp. · CLOSED TO ACCRUAL (as of 2024)
Tricuspid Valve Regurgitation; Tricuspid Valve Insufficiency; Tricuspid Valve Disease; Heart Valve Diseases; Cardiovascular Diseases; Heart Failure
NCT04482062
PI
Intra-procedural ECG changes during TAVR
Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2024)