Highlights
- 1JAMA neurology · 2024
- 2Proceedings of the National Academy of Sciences of the United States of America · 2020
- 3Science advances · 2024
Publications
163 publications
Funding
19 grantsView NIH portfolio on RePORTER ↗
Active
5 grants- PISBF 262079-01Utilization of focused ultrasound (FUS) technology for central nervous system (CNS) disorders.Sergey Brin Family Foundation · 2026–2029
- KPASAP-028295Using host-to-graft models to investigate alpha synuclein transsynaptic propagation.Michael J. Fox Foundation for Parkinson's Research · 2026–2028
- PIJPB 243206-03Gene Therapy for Neurorestoration and Neuroprotection in Parkinson's DiseaseJPB Foundation, The · 2024–2027
- PISA 251823-02Gene therapy for pain using novel AAV vectorsMeiraGTx, LLC · 2025–2027Contract
- PIBP 214669-01MeiraGTx Biopharma Alliance AgreementMeiraGTx, LLC · 2021–2027BioPharma Alliance
Completed grants (14)
- PIMJF 214365-03ASAP - Aligning Science Across Parkinson'sMichael J. Fox Foundation for Parkinson's Research · 2021–2025
- PIJPB 226700-03Gene therapy to address unmet needs in Parkinson's DiseaseJPB Foundation, The · 2021–2024
- PIAddgene 706164Addgene 706164Addgene, Inc. · 2022–2023
- Sub-PIR01NS097184-05Remote Electromagnetic Control of Neural Activity for Treatment of Parkinson's DiseaseNational Institute of Neurological Disorders and Stroke · 2016–2022 · via Rockefeller University
- PIJPBF 184517-03Gene therapy to address unmet needs in Parkinson's diseaseJPB Foundation, The · 2018–2021
- PIFUS585R1MRGFUS GENE DELIVERY FOR NEUROPROTECTION IN PARKINSON'S DISEASEFocused Ultrasound Foundation · 2018–2021
- PIMJFF 194725-01LRRK2 Activity and DyskinesiaMichael J. Fox Foundation for Parkinson's Research · 2019–2020
- KPAPDA 190167-01Menopause as an Important transition State in the Susceptibility to Parkinson's DiseaseAmerican Parkinson Disease Association · 2018–2020
- PI469Gene Therapy for Motor and Non-Motor Symptoms of Parkinson's DiseaseJPB Foundation, The · 2015–2018
- PI11601.01Supplement Role of LRRK2 in Levodopa-Induced DyskinesiaMichael J. Fox Foundation for Parkinson's Research · 2017–2018
- PINREF 183807-01Focused Ultrasound Mediated LDLR Gene Therapy for Alzheimer’s DiseaseNeurosurgery Research & Education Foundation · 2018–2018
- PIR01NS067414-04 EWXIAP Gene Therapy for Huntington's DiseaseNational Institute of Neurological Disorders and Stroke · 2010–2014
- PIR21NS055003-02Neuroprotection via XIAP gene therapy in Huntington's diseaseNINDS · 2006–2009 · via NIH RePORTER
- PIK08NS044978-05PTEN Anti-Oncogene Influences on Neuronal Function & ToxicityNINDS · 2004–2009 · via NIH RePORTER
Honors & distinctions
1 honor
- Member · American Society for Clinical Investigation · 2015
Clinical research
8 studies
Active
5 studies- PINCT03671889Assessment of Safety and Efficacy of ExAblate Blood-Brain Barrier Disruption for the Treatment of Patients With Probable Alzheimer's DiseaseNA · InSightec · OPEN TO ACCRUAL (as of 2025)Alzheimer Disease
- PINCT04197921A Feasibility Clinical Trial of Exablate for Low Intensity Focused Ultrasound Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Abuse Disorders (SUDs)NA · InSightec · OPEN TO ACCRUAL (as of 2025)Opioid-use Disorder; Substance Use Disorders
- PICranial MRI-Guided Focused Ultrasound â A Review of OutcomesWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)
- PINCT04728295Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)NA · InSightec · OPEN TO ACCRUAL (as of 2023)Parkinson Disease
- PINCT04991831A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's DiseaseInSightec · OPEN TO ACCRUAL (as of 2023)Tremor Associated With Tremor Dominant Parkinson's Disease
Completed & closed trials (3)
- PINCT04112381A Pivotal Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential TremorNA · InSightec · IRB STUDY CLOSURE (as of 2023)Essential Tremor
- PINCT03634007A 52-Week, Multicenter, Phase 1/2 Open-label Study to Evaluate the Safety of LX1001 in Participants With APOE4 Homozygote Alzheimer's DiseasePHASE1; PHASE2 · Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2023)Alzheimer Disease; Early Onset Alzheimer Disease
- PICOVID-19: Feasibility of using wearable devices in monitoring COVID-19 in_x000D_ healthcare professionalsWeill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2021)
Available technologies
2 technologiesView full WCM portfolio ↗
- Non-Invasive Delivery of CNS Gene Therapy Using Focused Ultrasound8560Application filed
- Non-Invasive Delivery of Oncolytic Viruses Using Focused Ultrasound8361Application filedPoC Data
News mentions
2 mentionsView all WCM news ↗
- Noninvasive Focused Ultrasound Treatment Can Ease Motor Symptoms of Parkinson’s DiseaseOctober 27, 2026
As Stan Au’s Parkinson’s disease symptoms progressed, everyday activities became daily battles. His hands shook so badly that he struggled to hold utensils and couldn’t sign his name. He stopped playing pickleball—a sport he once enjoyed—despite taking a widely prescribed medication for managing motor symptoms.
- A New Lease on Life: Procedure Relieves Patients’ Tremors in Both HandsOctober 24, 2024
An MRI-guided treatment for essential tremor is safe and effective in patients who already underwent the procedure for their dominant hand, a new study shows.
Media highlights
1 clip
- Cornell Profile Shows Benefits And Risks Of Ultrasound Treatment For Parkinson’sFingerLakes1.com · October 30, 2026
Mentoring
11 menteesAll publications with mentees →
5 MD students · 5 Postdocs · 1 early-career researcher
MD · 5
- NKNeerav KumarMD mentee · Class of 2026
- SNSofya NormanMD mentee · Class of 2023
- MYMelissa YuanMD mentee · Class of 2021
- GWGraham WinstonMD mentee · Class of 2020
- EJEric JurgensMD mentee · Class of 2019
Postdoc · 5
- DBDylan BarberaPostdoc mentee · 2023–2023
- LULouise UrienPostdoc mentee · 2022–2023
ECR · 1
- GKGary KocharianEarly career mentee · Class of 2018
External relationships
Ownership
Graviton Bioscience Corporation · MeiraGTx, LLC
Proprietary Interest
MeiraGTx, LLC
Other
Graviton Bioscience Corporation · MeiraGTx, LLC