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Scholars @ Weill Cornell Medicine

Help & supportPhase 1 prototype

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Scholars8,803 Publications201,348 Funding7,268 Clinical research190

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Browse

Scholars8,803 Publications201,348 Funding7,268 Clinical research190

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Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional166
Observational24

Phase

Not applicable138
Not reported24
Phase 311
Phase 28
Phase 46
Phase 2/33

Investigator

Jim W. Cheung10
Brian DeRubertis8
James E. Ip8
Geoffrey W Bergman6
Shmuel Chen6

Show all 50Show fewer

Department

Medicine83
Surgery31
Cardiothoracic Surgery11
Psychiatry11
Neurological Surgery10

Show all 17Show fewer

Condition

Atrial Fibrillation19
Heart Failure15
Stroke8
Cardiovascular Diseases7
Chronic Limb-Threatening Ischemia7

Intervention type

Device190
Drug807
Other202
Biological157
Procedure127
Behavioral83

Sponsor type

Industry139
WCM (investigator-initiated)31
Other academic18
Cooperative group1
NIH1

Start date

Has results posted41

Device×Clear all

Showing 21–40 of 190 studiesSort:

Active, not recruitingInterventional · Not applicableNCT04227899 ↗
LIFE-BTK (pivotaL Investigation of saFety and Efficacy of BRS Treatment-Below The Knee) Randomized Controlled Trial
Peter ConnollyPI
Intervention
Device: Esprit BTK Device · Device: Percutaneous Transluminal Angioplasty (PTA) Device
Dates
Aug 2020 – Aug 2023

FiltersClear all

Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional166
Observational24

Phase

Not applicable138
Not reported24
Phase 311
Phase 28
Phase 46
Phase 2/33

Investigator

Jim W. Cheung10
Brian DeRubertis8
James E. Ip8
Geoffrey W Bergman6
Shmuel Chen6

Show all 50Show fewer

Department

Medicine83
Surgery31
Cardiothoracic Surgery11
Psychiatry11
Neurological Surgery10

Show all 17Show fewer

Condition

Atrial Fibrillation19
Heart Failure15
Stroke8
Cardiovascular Diseases7
Chronic Limb-Threatening Ischemia7

Intervention type

Device190
Drug807
Other202
Biological157
Procedure127
Behavioral83

Sponsor type

Industry139
WCM (investigator-initiated)31
Other academic18
Cooperative group1
NIH1

Start date

Has results posted41

Device×Clear all

Showing 21–40 of 190 studiesSort:

Active, not recruitingInterventional · Not applicableNCT04227899 ↗
LIFE-BTK (pivotaL Investigation of saFety and Efficacy of BRS Treatment-Below The Knee) Randomized Controlled Trial
Peter ConnollyPI
Intervention
Device: Esprit BTK Device · Device: Percutaneous Transluminal Angioplasty (PTA) Device
Dates
Aug 2020 – Aug 2023

Manish Ashwin Parikh4

Mehraneh Dorna Jafari2

David Leslie Carr-Locke1

Daniel Joseph Holzwanger1

Obstetrics and Gynecology6

Rehabilitation Medicine6

Otolaryngology Head and Neck Surgery1

Radiation Oncology1

Show all 50

Show fewer

Ischemic Stroke7
Coronary Artery Disease6
Aortic Valve Stenosis4
Arrhythmias, Cardiac4
Bradycardia4
Chronic Pain4
Depression4
Heart Diseases4
Liver Diseases4
Mitral Valve Insufficiency4
Atrioventricular Block3
Carcinoma, Hepatocellular3
Depressive Disorder, Major3
Depressive Disorder, Treatment-Resistant3
Heart Valve Diseases3
Neoplasms3
Prostatic Neoplasms3
Pulmonary Arterial Hypertension3
Tricuspid Valve Insufficiency3
Alzheimer Disease2
Angina Pectoris2
Anxiety Disorders2
Aortic Aneurysm, Thoracoabdominal2
Blood Loss, Surgical2
Cognitive Dysfunction2
Colonic Neoplasms2
Death, Sudden, Cardiac2
Dissection, Thoracic Aorta2
Fatigue2
Gastric Outlet Obstruction2
Heart Failure, Diastolic2
Hypertension2
Liver Neoplasms2
Lung Diseases, Interstitial2
Nail Diseases2
Obesity2
Parkinson Disease2
Peripheral Arterial Disease2
Recurrence2
Tachycardia, Ventricular2
Varicose Ulcer2
Vascular Diseases2
Venous Thrombosis2
Acute Coronary Syndrome1
Acute Kidney Injury1

Radiation

Diagnostic test31

Dietary supplement14

Combination product11

Genetic7

· Results posted

Sponsor

Abbott Cardiovascular Systems, Inc.

Critical Limb Ischemia (CLI)

RecruitingInterventional · Not applicableNCT04339699 ↗

STITCH - Prospective Multi Center Comparative Parallel Concurrent Study of the NobleStitch EL Compared to FDA Approved Amplatzer Occluder Device for Closure of Patent Foramen Ovale to Prevent Recurrent Ischemic Stroke

Harsimran SinghPI

Intervention: Device: NobleStitch™EL Suture Mediated Closure System · Device: Amplatzer PFO Occluder
Dates: Jan 2021 – Dec 2026 (est.)
Sponsor: Nobles Medical Technologies II, Inc.

Foramen Ovale, PatentStroke, Ischemic

Active, not recruitingInterventional · Not applicableNCT04375332 ↗

A Prospective, Multi-center Trial to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair With the HARPOON™ System (RESTORE)

Stephanie L. MickPI

Intervention: Device: HARPOON™ Beating Heart Mitral Valve Repair System
Dates: Dec 2020 – Dec 2027 (est.)
Sponsor: Edwards Lifesciences Corp.

Mitral Regurgitation

Active, not recruitingInterventional · Not applicableNCT04482062 ↗

Edwards EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device

Shmuel ChenPI

Intervention: Device: Edwards EVOQUE System · Drug: Optimal Medical Therapy
Dates: Apr 2021 – Dec 2025
Sponsor: Edwards Lifesciences Corp.

Tricuspid Valve RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease+3 more

Active, not recruitingInterventional · Not applicableNCT04489823 ↗

PARADIGM PARAvalvular Leak Closure With the Amplatzer Valvular Plug occluDer for Interventional Transcatheter Closure for PVL With Surgical bioloGical and Mechanical Heart Valve

Geoffrey W BergmanPI

Intervention: Device: AVP III
Dates: Dec 2020 – Nov 2025
Sponsor: Abbott Cardiovascular Systems, Inc.

Paravalvular Aortic Regurgitation

RecruitingInterventional · Not applicableNCT04555161 ↗

An Early Feasibility Study Assessing Treatment of Pulmonary Hypertension Using the Aria CV Pulmonary Hypertension System

Evelyn M. HornPI

Intervention: Device: Aria CV Pulmonary Hypertension System
Dates: Mar 2021 – Oct 2025 (est.)
Sponsor: Aria CV, Inc.

Pulmonary Arterial HypertensionPulmonary HypertensionRight Heart Dysfunction

RecruitingInterventional · Not applicableNCT04592445 ↗

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction: Randomized Controlled Feasibility Trial - The Rebalance HF Study

Parag GoyalPI

Intervention: Device: Greater Splanchnic Nerve Ablation · Device: Sham Control
Dates: Dec 2020 – Jan 2028 (est.)
Sponsor: Axon Therapies, Inc

Heart Failure With Preserved Ejection Fraction (HFpEF

RecruitingObservationalNCT04674969 ↗

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature (ELEGANCE)

Brian DeRubertisPI

Intervention: Device: Any eligible commercially available Boston Scientific Corporation (BSC) drug-eluting device.
Dates: Mar 2021 – Jan 2028 (est.)
Sponsor: Boston Scientific Corporation

Peripheral Vascular Diseases

Active, not recruitingInterventional · Not applicableNCT04722250 ↗

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

Geoffrey W BergmanPI

Intervention: Device: Medtronic Evolut PRO, Evolut PRO+ or Evolut FX (where commercially available) TAV Systems · Device: Edwards SAPIEN 3 or SAPIEN 3 Ultra THV Systems
Dates: Apr 2021 – Nov 2023· Results posted
Sponsor: Medtronic, Inc.

Symptomatic Aortic StenosisAortic Valve StenosisAortic Valve Replacement

Active, not recruitingInterventional · Not applicableNCT04728295 ↗

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

Michael G KaplittPI

Intervention: Device: Exablate 4000
Dates: May 2021 – Mar 2024
Sponsor: InSightec

Parkinson Disease

Active, not recruitingInterventional · Not applicableNCT04818645 ↗

Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients (ASSERT-AF)

Gioia TurittoPI

Intervention: Device: ASSERT Insertable Cardiac Monitor · Other: Conventional Management and monitoring
Dates: Jan 2023 – Jul 2028 (est.)
Sponsor: University of Rochester

Atrial FibrillationHeart Failure

RecruitingInterventional · Not applicableNCT04891510 ↗

A Comparative Analysis of REVOLVE, LipoGrafter, and Viality in Autologous Fat Grafting During Breast Surgery

David M. OtterburnPI

Intervention: Device: REVOLVE Advanced Adipose System · Device: LipoGrafter · Procedure: Viality
Dates: May 2021 – Jun 2028 (est.)
Sponsor: Weill Medical College of Cornell University

MastectomyMammaplastyBreast Reconstruction

Enrolling by invitationInterventional · Phase 3NCT04905693 ↗

An Open-label Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (TETON-OLE)

Anna PodolanczukPI

Intervention: Drug: Inhaled Treprostinil · Device: Treprostinil Ultrasonic Nebulizer
Dates: Sep 2022 – Dec 2029 (est.)
Sponsor: United Therapeutics

Idiopathic Pulmonary FibrosisInterstitial Lung DiseaseProgressive Pulmonary Fibrosis

Enrolling by invitationInterventional · Not applicableNCT04982757 ↗

Accelerated TMS for Depression and OCD

Conor ListonPI

Intervention: Device: MagVenture MagPro System with Brainsight neuronavigation device
Dates: Dec 2021 – May 2027 (est.)
Sponsor: Weill Medical College of Cornell University

DepressionOCD

RecruitingObservationalNCT04991831 ↗

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

Michael G KaplittPI

Intervention: Device: Unilateral thalamotomy
Dates: Apr 2022 – Dec 2027 (est.)
Sponsor: InSightec

Tremor Associated With Tremor Dominant Parkinson's Disease

Active, not recruitingInterventional · Not applicableNCT05051033 ↗

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Stephanie L. MickPI

Intervention: Procedure: Mitral valve repair · Device: Transcatheter edge-to-edge repair
Dates: Feb 2022 – Jun 2029 (est.)
Sponsor: Icahn School of Medicine at Mount Sinai

Mitral Valve Regurgitation

RecruitingInterventional · Not applicableNCT05064709 ↗

Assessment of Implantable CCM in the Heart Failure Group With Higher Ejection Fraction

James E. IpPI

Intervention: Device: Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System · Device: OPTIMIZER™ Smart Mini System
Dates: Feb 2022 – Feb 2029 (est.)
Sponsor: Impulse Dynamics USA, Inc.

Heart FailureHeart Failure With Preserved Ejection FractionHeart Failure With Mid Range Ejection Fraction+2 more

Active, not recruitingInterventional · Phase 4NCT05079841 ↗

The Stimulation To Induce Mothers (STIM) Study: A Parallel Group Randomized Controlled Trial

Moeun SonPI

Intervention: Device: Electric breast pump · Drug: Exogenous oxytocin intravenous infusion without nipple stimulation.
Dates: Nov 2021 – Nov 2028 (est.)
Sponsor: Yale University

OxytocinLabor PainInduction of Labor Affected Fetus / Newborn+1 more

RecruitingObservationalNCT05085704 ↗

Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease

Juan M. PascualPI

Intervention: Device: Magnetic resonance imaging
Dates: May 2022 – Jun 2029 (est.)
Sponsor: Weill Medical College of Cornell University

Glut1 Deficiency Syndrome 1Glucose Metabolism DisordersEpilepsy+4 more

RecruitingInterventional · Not applicableNCT05102019 ↗

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Jaikirshan KhatriPI

Intervention: Device: Arm 1: treatment with Shockwave Reducer · Other: Arm 2 (control): Implantation procedure with no device implanted · Device: Arm 3 (unblinded, non-randomized): Single arm registry
Dates: Jan 2022 – Jul 2027 (est.)
Sponsor: Shockwave Medical INC

Refractory Angina

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