Highlights
- 1
- 2American journal of respiratory and critical care medicine · 2022
- 3
Publications
108 publications
Funding
10 grantsView NIH portfolio on RePORTER ↗
Active
7 grants- PIR01HL185515-01Multi-omic profiling of pulmonary fibrosis and cardiovascular diseaseNational Heart, Lung, and Blood Institute · 2026–2031
- PISRA 245118-01Retrospective EValuation in US of e-Lung in PPF - REVISE PPFBrainomix · 2024–2029Contract
- Sub-PIHT9425-25-1-0982Metformin to Attenuate ProgressiVe RespIratory Decline in Idiopathic Pulmonary Fibrosis (MAVRIC-IPF)U.S. Department of Defense · 2025–2029 · via University of Massachusetts Medical School
- Sub-PIR33HL158540-04Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsNational Heart, Lung, and Blood Institute · 2024–2027 · via University of Massachusetts Medical School
- MPIU24HL145265-06Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyNational Heart, Lung, and Blood Institute · 2021–2027 · via The Regents of the University of Michigan
- Sub-PIHT9425-25-1-0982Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis (MAVRIC-IPF)U.S. Department of Defense · 2025–2026 · via University of North Carolina at Chapel Hill
- Sub-PIVUMC 240491-01Phase II: B4PF Imaging InitiativeThree Lakes Foundation · 2023–2025 · via Vanderbilt University Medical Center
Completed grants (3)
- PIK23HL140199-04Role of High Density Lipoproteins in Interstitial Lung DiseaseNational Heart, Lung, and Blood Institute · 2020–2024Career
- Co-IR61HL158540-01A1Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsNational Heart, Lung, and Blood Institute · 2022–2024
- PITLF 225482-01B4PF Imaging InitiativeThree Lakes Foundation · 2022–2023
Clinical research
15 studies
Active
8 studies- PINCT06951217A Multinational, Long-Term, Safety and Tolerability, Open-Label Extension Study of Subjects Who Have Participated in Avalyn Pharma Studies of Inhaled Antifibrotic Agents (AP-LTE-008 [SAIL])PHASE2 · Avalyn Pharma, Inc. · OPEN TO ACCRUAL (as of 2026)Progressive Pulmonary Fibrosis; Idiopathic Pulmonary Fibrosis (IPF)
- PIMulti-omic Profiling of pulmonary fibrosis and cardiovascular diseaseWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
- PINCT07201922A Double Blind, Randomized, Placebo-controlled Exploratory Trial to Investigate the Efficacy and Safety of Nerandomilast Over 24 Months When Administered in Individuals With Interstitial Lung Abnormalities and a Family History of Pulmonary Fibrosis to Reduce the Risk of Worsening (DROP-FPF)PHASE3 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · OPEN TO ACCRUAL (as of 2026)Familial Pulmonary Fibrosis; Interstitial Lung Abnormalities; Interstitial Lung Diseases
- PIEvaluating pulmonary fibrosis with optical coherence tomography: Pilot StudyThe General Hospital Corporation (dba Massachusetts General Hospital) · OPEN TO ACCRUAL (as of 2026)
- PINCT04905693An Open-label Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease (TETON-OLE)PHASE3 · United Therapeutics · OPEN TO ACCRUAL (as of 2025)Idiopathic Pulmonary Fibrosis; Interstitial Lung Disease; Progressive Pulmonary Fibrosis
- PINCT06329401A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study Evaluating the Safety and Efficacy of Pirfenidone Solution for Inhalation (AP01) in Participants With PPFPHASE2 · Avalyn Pharma, Inc. · OPEN TO ACCRUAL (as of 2024)Pulmonary Fibrosis; Progressive Pulmonary Fibrosis; Pulmonary Fibrosis Secondary to Systemic Sclerosis; Pulmonary Fibrosis, Interstitial Lung Disease; Interstitial Lung Disease; Interstitial Lung Disease Due to Connective Tissue Disease (Disorder); Interstitial Lung Disease in Patients With Rheumatoid Arthritis; Interstitial Lung Disease With Progressive Fibrotic Phenotype in Diseases Classified Elsewhere; Hypersensitivity Pneumonitis; Interstitial Lung Disease With Systemic Sclerosis
- PINCT05943535A Randomized, Double-blind, Placebo-controlled, Multinational, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)PHASE3 · United Therapeutics · OPEN TO ACCRUAL (as of 2024)Progressive Pulmonary Fibrosis; Interstitial Lung Disease
- PIExosome Profiling to Reveal Circulating Protein Biomarkers of Interstitial Lung Disease and Chronic Obstructive Pulmonary DiseaseWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2022)
Completed & closed trials (7)
- PINCT04300920Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) TrialPHASE3 · University of Massachusetts Medical School · IRB STUDY CLOSURE (as of 2026)Idiopathic Pulmonary Fibrosis
- PINCT06317285A Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study (TRANSFORM) to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)PHASE2 · GlaxoSmithKline · IRB STUDY CLOSURE (as of 2026)Idiopathic Pulmonary Fibrosis
- PINCT06097260A Randomized, Double-blind, Dose-ranging, Placebo-controlled Study to Evaluate the Efficacy and Safety of Bexotegrast (PLN-74809) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON-IPF)PHASE2 · Pliant Therapeutics, Inc · IRB STUDY CLOSURE (as of 2026)Idiopathic Pulmonary Fibrosis
- PINCT05195918Dose Ranging Study of Oral Epigallocatechin-3-gallate (EGCG) Given Daily for 12 Weeks to Patients With Idiopathic Pulmonary Fibrosis (IPF) Evaluating Safety, PK Interactions With Standard of Care Drugs, and Biomarkers of Drug EffectPHASE1 · University of California, San Francisco · CLOSED TO ACCRUAL (as of 2025)Idiopathic Pulmonary Fibrosis
- PIRetrospective EValuation in US of e-Lung in PPFBrainomix · CLOSED TO ACCRUAL (as of 2025)
- PIPFF Registry Ancillary Study: Role of High Density Lipoproteins in Interstitial Lung_x000D_ DiseaseWeill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2022)
- PIHousehold Dust Microbiome and Idiopathic Pulmonary FibrosisWeill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2021)
External relationships
Advisory/Scientific Board Member
Avalyn Pharma, Inc. · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · Brainomix · Nelum Pharmaceuticals · PureTech Health · Three Lakes Foundation · United Therapeutics
Speaker/Lecturer
BTIG, LLC · PeerDirect
Other Interest
Trevi Therapeutics
Other
Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · EBSCO · Eisai, Inc. · Imvaria Inc. · Pliant Therapeutics, Inc · PureTech Health · Regeneron Pharmaceuticals, Inc. · Roche Pharmaceuticals, Inc. · Veracyte, Inc.