Co-authored publications with mentees

Olivier Elemento, PhD · 129 publications across 20 mentees

CSV Word

MD mentee

Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in TP53-Mutated Diffuse Large B-Cell Lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
OEOlivier ElementoMUManik UppalBBBhavneet BhinderARAndrew R MardersteinLMLorenzo M. Falchi+9 more →
PMID: 42054619DOI5 citations
With Manik Uppal · MD mentee · Class of 2020
Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.
bioRxiv : the preprint server for biology · 2025
OEOlivier ElementoKFKyle FinosJKJunbum KimHRHiranmayi Ravichandran LYLiron Yoffe+5 more →
PMID: 40027685PMCID: PMC11870609DOI
With Kyle Finos · MD mentee · Class of 2025
Immunogenomic Landscape of Neuroendocrine Prostate Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
OEOlivier ElementoMUManik UppalASAndrea Sboner JMJuan Miguel Mosquera HBHimisha Beltran
PMID: 37223924PMCID: PMC10524949DOI41 citations
With Manik Uppal · MD mentee · Class of 2020
Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells.
Blood cancer discovery · 2023
OEOlivier ElementoMUManik UppalJZJenny Zhaoying Xiang ECEthel Cesarman+1 more →LGLisa Giulino Roth
PMID: 36723991PMCID: PMC10150291DOI54 citations
With Manik Uppal · MD mentee · Class of 2020
The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.
Cancer research · 2023
OEOlivier ElementoMUManik UppalWLWeisi LiuFKFrancesca Khani+2 more →BMBishoy Morris Faltas
PMID: 36480186DOI30 citations
With Manik Uppal · MD mentee · Class of 2020
Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial.
The Lancet. Oncology · 2021
OEOlivier ElementoMUManik UppalNKNasser K Altorki TETimothy E. McGraw+11 more →SCSilvia Chiara Formenti
PMID: 34015311DOI325 citations
With Manik Uppal · MD mentee · Class of 2020
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
Nature communications · 2020
OEOlivier ElementoMUManik UppalARAndrew R MardersteinAVAkanksha VermaZTZakieh Tayyebi+1 more →
PMID: 32371927PMCID: PMC7200670DOI32 citations
With Manik Uppal · MD mentee · Class of 2020

PhD mentee

A Real-Time Image-Based Co-Culture Assay to Quantify Tumor-Infiltrating Lymphocyte-Mediated Apoptotic Killing of Patient-Derived Tumor Organoids.
Journal of visualized experiments : JoVE · 2026
OEOlivier ElementoADAlyssa Duren-LubanskiEPEnrique PodazaMLM. Laura Martin BDBenjamin David Hopkins
PMID: 42695604DOI
With Alyssa Duren-Lubanski · Cell & Developmental Biology (PhD)
Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.
Science advances · 2026
OEOlivier ElementoHKHui-Hsuan KuoBBBhavneet BhinderHNHamza N Gokozan+32 more →MLM. Laura Martin
PMID: 42361179PMCID: PMC13308604DOI1 citations
With Hui-Hsuan Kuo · Pharmacology (PhD) · Class of 2025
Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.
Science advances · 2026
OEOlivier ElementoVGValerie GallegosHKHui-Hsuan KuoBBBhavneet Bhinder+32 more →MLM. Laura Martin
PMID: 42361179PMCID: PMC13308604DOI1 citations
With Valerie Gallegos · Molecular Biology (PhD)
Intravesical mesothelin-based CAR T cells targeting MUC16 effectively control bladder cancer in preclinical models.
The Journal of experimental medicine · 2026
OEOlivier ElementoADAlyssa Duren-LubanskiJFJonathan F. KhanWCWinson Cai+7 more →TMTaha Merghoub
PMID: 42360231DOI1 citations
With Alyssa Duren-Lubanski · Cell & Developmental Biology (PhD)
Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC.
Cell reports methods · 2026
OEOlivier ElementoHKHui-Hsuan KuoEPEnrique PodazaGMGeoffrey Markowitz+8 more →MLM. Laura Martin
PMID: 42134319PMCID: PMC13282660DOI1 citations
With Hui-Hsuan Kuo · Pharmacology (PhD) · Class of 2025
Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC.
Cell reports methods · 2026
OEOlivier ElementoADAlyssa Duren-LubanskiEPEnrique PodazaHKHui-Hsuan Kuo+8 more →MLM. Laura Martin
PMID: 42134319PMCID: PMC13282660DOI1 citations
With Alyssa Duren-Lubanski · Cell & Developmental Biology (PhD)
Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in TP53-Mutated Diffuse Large B-Cell Lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
OEOlivier ElementoARAndrew R MardersteinMUManik UppalBBBhavneet Bhinder LMLorenzo M. Falchi+9 more →
PMID: 42054619DOI5 citations
With Andrew Marderstein · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2021
Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort.
Communications medicine · 2026
OEOlivier ElementoHKHui-Hsuan KuoMAMajd Al AssaadDGDaniela Guevara+11 more →JMJuan Miguel Mosquera
PMID: 41526458PMCID: PMC12796271DOI2 citations
With Hui-Hsuan Kuo · Pharmacology (PhD) · Class of 2025
PD-1 is requisite for skin T_RM cell formation and specification by TGFβ.
Nature immunology · 2025
OEOlivier ElementoAVAkanksha VermaAJAbhinav JaiswalNANiroshana Anandasabapathy
PMID: 40730902PMCID: PMC12307224DOI21 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.
Cancer research · 2025
OEOlivier ElementoCPColin P TangRMRachel MartiniJNJohn Nguyen+8 more →MLM. Laura Martin
PMID: 39891928PMCID: PMC11790258DOI19 citations
With Colin Tang · Pharmacology (PhD) · Class of 2021
IRE1α-XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs.
Nature immunology · 2025
OEOlivier ElementoAVAkanksha VermaAMAri M. Melnick
PMID: 39789376DOI16 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS.
bioRxiv : the preprint server for biology · 2024
OEOlivier ElementoYSYajas ShahEEEric E GardnerCZChen ZhangHEHarold E. Varmus
PMID: 37873210PMCID: PMC10592623DOI
With Yajas Shah · Physiology, Biophysics & Systems Biology (PhD) · Class of 2023
Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
OEOlivier ElementoYSYajas Shah
PMID: 37725593PMCID: PMC10690140DOI22 citations
With Yajas Shah · Physiology, Biophysics & Systems Biology (PhD) · Class of 2023
BTG1 mutation yields supercompetitive B cells primed for malignant transformation.
Science (New York, N.Y.) · 2023
OEOlivier Elemento ASAshley Stephen DoaneCMCoraline MlynarczykMTMatt Teater+13 more →AMAri M. Melnick
PMID: 36656933PMCID: PMC10515739DOI40 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
An atlas of substrate specificities for the human serine/threonine kinome.
Nature · 2023
OEOlivier ElementoTMTomer M YaronKLKatarina LiberatoreDCDaniel Cizin+5 more →LCLewis C Cantley
PMID: 36631611PMCID: PMC9876800DOI523 citations
With Tomer Yaron · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Science signaling · 2022
OEOlivier ElementoTMTomer M YaronJLJared L JohnsonBMBenjamin M CohenKLKatarina Liberatore+10 more →
PMID: 36282911PMCID: PMC9830954DOI66 citations
With Tomer Yaron · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.
Cell reports · 2022
OEOlivier Elemento ASAshley Stephen DoaneMMMarek M DrozdzJBJakyung Bang+4 more →JZJonathan Zippin
PMID: 36170819PMCID: PMC9549417DOI9 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Characterization of Genetic Risk of End-Stage Knee Osteoarthritis Treated with Total Knee Arthroplasty: A Genome-Wide Association Study.
The Journal of bone and joint surgery. American volume · 2022
OEOlivier ElementoSKScott KulmDADavid A KolinMBMathias Bostrom TSTony S. Shen
PMID: 36000784DOI12 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Next generation patient derived tumor organoids.
Translational research : the journal of laboratory and clinical medicine · 2022
OEOlivier ElementoHKHui-Hsuan KuoEPEnrique PodazaJNJohn NguyenMLM. Laura Martin
PMID: 35964899DOI18 citations
With Hui-Hsuan Kuo · Pharmacology (PhD) · Class of 2025
Alterations in transcriptional networks in cancer: the role of noncoding somatic driver mutations.
Current opinion in genetics & development · 2022
OEOlivier Elemento ASAshley Stephen Doane
PMID: 35609422DOI4 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.
The Journal of experimental medicine · 2022
OEOlivier Elemento DRDavid Redmond RZRoberta Zappasodi DHDaniel Hirschhorn+3 more →TMTaha Merghoub
PMID: 35604411PMCID: PMC9130031DOI39 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
The lactate-NAD⁺ axis activates cancer-associated fibroblasts by downregulating p62.
Cell reports · 2022
OEOlivier ElementoHKHui-Hsuan KuoJFJuan Francisco Linares Rodriguez TDTania Diaz+5 more →MTMaria T. Diaz-Meco
PMID: 35545049PMCID: PMC9136538DOI73 citations
With Hui-Hsuan Kuo · Pharmacology (PhD) · Class of 2025
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy.
iScience · 2022
OEOlivier Elemento DRDavid RedmondLBLissenya B ArguetaLLLauretta Lacko+11 more →HSHeidi Stuhlmann
PMID: 35434541PMCID: PMC8996470DOI84 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Simple Linear Cancer Risk Prediction Models With Novel Features Outperform Complex Approaches.
JCO clinical cancer informatics · 2022
OEOlivier ElementoSKScott KulmJMJason Mezey
PMID: 35239414PMCID: PMC8920463DOI11 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms.
Frontiers in cell and developmental biology · 2022
OEOlivier Elemento ASAshley Stephen DoaneRMRaúl Martinez-McFalineJYJun Yao+3 more →YHYariv Houvras
PMID: 35223844PMCID: PMC8866878DOI6 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Pan-cancer analysis reveals molecular patterns associated with age.
Cell reports · 2021
OEOlivier ElementoARAndrew R MardersteinYSYajas ShahJWJessica WhiteJGJuan Garcia-Medina
PMID: 34879281DOI61 citations
With Andrew Marderstein · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2021
Pan-cancer analysis reveals molecular patterns associated with age.
Cell reports · 2021
OEOlivier ElementoYSYajas ShahARAndrew R MardersteinJWJessica WhiteJGJuan Garcia-Medina
PMID: 34879281DOI61 citations
With Yajas Shah · Physiology, Biophysics & Systems Biology (PhD) · Class of 2023
Publisher Correction: Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank.
Scientific reports · 2021
OEOlivier ElementoSKScott KulmDADavid A Kolin
PMID: 34845243PMCID: PMC8630148DOI
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Prediction of primary venous thromboembolism based on clinical and genetic factors within the U.K. Biobank.
Scientific reports · 2021
OEOlivier ElementoSKScott KulmDADavid A Kolin
PMID: 34725413PMCID: PMC8560817DOI28 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.
Advanced materials (Deerfield Beach, Fla.) · 2021
OEOlivier Elemento ASAshley Stephen Doane MLM. Laura MartinFMFlorencia M RowdoNBNicholas Brady+4 more →
PMID: 34676924PMCID: PMC8820841DOI76 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Dissecting bulk transcriptomes of diffuse large B cell lymphoma.
Cancer cell · 2021
OEOlivier ElementoDRDylan R McNallyAMAri M. Melnick
PMID: 34597590DOI4 citations
With Dylan McNally · Physiology, Biophysics & Systems Biology (PhD) · Class of 2024
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity.
Nature immunology · 2021
OEOlivier Elemento ASAshley Stephen Doane AAAlicia Alonso EAEftychia Apostolou AMAri M. Melnick
PMID: 34556886PMCID: PMC9829245DOI16 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.
Journal of virology · 2021
OEOlivier Elemento ASAshley Stephen DoaneAGAdrien GrimontDBDaniel Blanco-MeloRERobert E. Schwartz+2 more →
PMID: 34523966PMCID: PMC8577386DOI80 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Cell reports · 2021
OEOlivier ElementoDRDylan R McNallyCGChristopher Gaffney BDBrian D. Robinson+2 more →CBChristopher Barbieri
PMID: 34496233PMCID: PMC8477443DOI33 citations
With Dylan McNally · Physiology, Biophysics & Systems Biology (PhD) · Class of 2024
A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.
American journal of human genetics · 2021
OEOlivier ElementoSKScott KulmARAndrew R MardersteinRTRulla Tamimi
PMID: 34363748PMCID: PMC8456164DOI12 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
A polygenic-score-based approach for identification of gene-drug interactions stratifying breast cancer risk.
American journal of human genetics · 2021
OEOlivier ElementoARAndrew R MardersteinSKScott KulmRTRulla Tamimi
PMID: 34363748PMCID: PMC8456164DOI12 citations
With Andrew Marderstein · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2021
Artificial intelligence in oncology: From bench to clinic.
Seminars in cancer biology · 2021
OEOlivier ElementoJEJamal Elkhader
PMID: 33915289DOI33 citations
With Jamal Elkhader · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter.
medRxiv : the preprint server for health sciences · 2021
OEOlivier ElementoSKScott KulmSASajjad AbedianRMRachel Martini+11 more →MBMelissa Boneta Davis
PMID: 33851193PMCID: PMC8043490DOI
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology · 2021
OEOlivier Elemento ASAshley Stephen Doane CMCem Meydan CCChristopher Chin+6 more →AMAri M. Melnick
PMID: 33432228PMCID: PMC7855695DOI33 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology · 2021
OEOlivier ElementoDRDylan R McNallyCMCem Meydan CCChristopher Chin+6 more →AMAri M. Melnick
PMID: 33432228PMCID: PMC7855695DOI33 citations
With Dylan McNally · Physiology, Biophysics & Systems Biology (PhD) · Class of 2024
Leveraging phenotypic variability to identify genetic interactions in human phenotypes.
American journal of human genetics · 2020
OEOlivier ElementoSKScott KulmARAndrew R Marderstein
PMID: 33326753PMCID: PMC7820920DOI50 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Leveraging phenotypic variability to identify genetic interactions in human phenotypes.
American journal of human genetics · 2020
OEOlivier ElementoARAndrew R MardersteinSKScott Kulm
PMID: 33326753PMCID: PMC7820920DOI50 citations
With Andrew Marderstein · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2021
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Nature · 2020
OEOlivier Elemento ASAshley Stephen DoaneNYNevin YusufovaMTMatt Teater+9 more →AMAri M. Melnick
PMID: 33299181PMCID: PMC7855728DOI204 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage.
Molecular cell · 2020
OEOlivier Elemento ASAshley Stephen Doane LALucy A SkrabanekMRMatthew R TeaterAMAri M. Melnick
PMID: 33232656PMCID: PMC7737631DOI30 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Clinical, regional, and genetic characteristics of Covid-19 patients from UK Biobank.
PloS one · 2020
OEOlivier ElementoSKScott KulmDADavid A KolinPJPaul J Christos
PMID: 33201886PMCID: PMC7671499DOI39 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis.
Nature · 2020
OEOlivier Elemento DRDavid Redmond DTDuc-Huy Tran Nguyen RSRyan Schreiner+13 more →SRShahin Rafii
PMID: 32908310PMCID: PMC7480005DOI234 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro.
bioRxiv : the preprint server for biology · 2020
OEOlivier ElementoTMTomer M YaronJLJared L JohnsonBMBenjamin M CohenKLKatarina Liberatore+9 more →
PMID: 32817937PMCID: PMC7430567DOI
With Tomer Yaron · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma.
Leukemia · 2020
OEOlivier Elemento DRDavid RedmondKNKui NieKWKenneth W Eng+2 more →WTWayne Tam
PMID: 32788647DOI15 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts.
Transplantation direct · 2020
OEOlivier ElementoAVAkanksha VermaBJBryan J DooleyHYHua Yang+3 more →MSManikkam Suthanthiran
PMID: 32766436PMCID: PMC7377920DOI10 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
A machine learning and network framework to discover new indications for small molecules.
PLoS computational biology · 2020
OEOlivier ElementoCGCoryandar GilvaryJEJamal ElkhaderNMNeel MadhukarCHClaire Henchcliffe+1 more →
PMID: 32764756PMCID: PMC7437923DOI18 citations
With Coryandar Gilvary · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
A machine learning and network framework to discover new indications for small molecules.
PLoS computational biology · 2020
OEOlivier ElementoJEJamal ElkhaderCGCoryandar GilvaryNMNeel MadhukarCHClaire Henchcliffe+1 more →
PMID: 32764756PMCID: PMC7437923DOI18 citations
With Jamal Elkhader · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.
Scientific reports · 2020
OEOlivier ElementoAVAkanksha VermaEREdd RickerRMRossella Marullo+4 more →ABAlessandra B. Pernis
PMID: 32753663PMCID: PMC7403583DOI10 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Clinical and Genetic Characteristics of Covid-19 Patients from UK Biobank.
medRxiv : the preprint server for health sciences · 2020
OEOlivier ElementoSKScott KulmDADavid A Kolin
PMID: 32511589PMCID: PMC7276016DOI480 citations
With Scott Kulm · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations.
Cancers · 2020
OEOlivier ElementoAVAkanksha VermaMBMelissa Boneta DavisRMRachel MartiniLALisa Ann Newman+1 more →
PMID: 32414099PMCID: PMC7281131DOI32 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
Nature communications · 2020
OEOlivier ElementoAVAkanksha VermaARAndrew R MardersteinMUManik UppalZTZakieh Tayyebi+1 more →
PMID: 32371927PMCID: PMC7200670DOI32 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
Nature communications · 2020
OEOlivier ElementoARAndrew R MardersteinMUManik UppalAVAkanksha VermaZTZakieh Tayyebi+1 more →
PMID: 32371927PMCID: PMC7200670DOI32 citations
With Andrew Marderstein · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2021
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes.
Nature communications · 2020
OEOlivier Elemento DRDavid Redmond JEJonathan E. ShoagATAlexis Te+4 more →CBChristopher Barbieri
PMID: 32332823PMCID: PMC7181734DOI64 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
CIC is a critical regulator of neuronal differentiation.
JCI insight · 2020
OEOlivier ElementoHPHeng PanIHInah HwangHZHongwu Zheng JPJihye Paik
PMID: 32229723PMCID: PMC7253013DOI33 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK^- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.
Leukemia · 2020
OEOlivier ElementoAVAkanksha VermaGGGiorgio Ga. Inghirami
PMID: 32123306DOI16 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Urinary cell transcriptomics and acute rejection in human kidney allografts.
JCI insight · 2020
OEOlivier ElementoAVAkanksha VermaTMThangamani Muthukumar HYHua Yang+10 more →MSManikkam Suthanthiran
PMID: 32102984PMCID: PMC7101135DOI45 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The aging skin microenvironment dictates stem cell behavior.
Proceedings of the National Academy of Sciences of the United States of America · 2020
OEOlivier ElementoAVAkanksha VermaSGShiri Gur-CohenJGJames Glenn Krueger
PMID: 32094197PMCID: PMC7071859DOI160 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.
Cell reports · 2020
OEOlivier ElementoAVAkanksha VermaSYShira YomtoubianFIFranco Izzo+9 more →VMVivek Mittal
PMID: 31968251DOI92 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Graph convolutional networks for computational drug development and discovery.
Briefings in bioinformatics · 2020
OEOlivier ElementoCGCoryandar GilvarySZSendong ZhaoFWFei Wang
PMID: 31155636DOI388 citations
With Coryandar Gilvary · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse.
Blood cancer journal · 2019
OEOlivier Elemento DRDavid Redmond ANAnna NamKNKui Nie+1 more →WTWayne Tam
PMID: 31434873PMCID: PMC6704167DOI4 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.
The American journal of pathology · 2019
OEOlivier ElementoAVAkanksha VermaNMNeil M IyengarMSMaxine S JochelsonXKXi Kathy Zhou+1 more →
PMID: 31323189PMCID: PMC6880774DOI78 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts.
JCI insight · 2019
OEOlivier ElementoAVAkanksha VermaHYHua Yang MLMichelle Lubetzky+6 more →TMThangamani Muthukumar
PMID: 31292297PMCID: PMC6629252DOI46 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The Missing Pieces of Artificial Intelligence in Medicine.
Trends in pharmacological sciences · 2019
OEOlivier ElementoCGCoryandar GilvaryJEJamal Elkhader
PMID: 31277839DOI71 citations
With Coryandar Gilvary · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
The Missing Pieces of Artificial Intelligence in Medicine.
Trends in pharmacological sciences · 2019
OEOlivier ElementoJEJamal ElkhaderCGCoryandar Gilvary
PMID: 31277839DOI71 citations
With Jamal Elkhader · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2022
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Cancer cell · 2019
OEOlivier Elemento ASAshley Stephen Doane BDBrian D. Robinson HBHimisha Beltran+2 more →CBChristopher Barbieri
PMID: 31085180DOI27 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.
Molecular cancer · 2019
OEOlivier ElementoAVAkanksha VermaXCXiang Chen ZCZhengming Chen+2 more →NDNancy Du
PMID: 31072393PMCID: PMC6506944DOI44 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Supplemental estrogen and caloric restriction reduce obesity-induced periprostatic white adipose inflammation in mice.
Carcinogenesis · 2019
OEOlivier ElementoAVAkanksha VermaPBPriya BhardwajXKXi Kathy Zhou+3 more →AJAndrew J Dannenberg
PMID: 31067318PMCID: PMC7331453DOI19 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
OEOlivier ElementoAVAkanksha Verma
PMID: 30979734PMCID: PMC6726529DOI74 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Cancer cell · 2019
OEOlivier Elemento ASAshley Stephen DoaneMAMichael A AugelloDLDeli Liu+6 more →CBChristopher Barbieri
PMID: 30930119PMCID: PMC6467783DOI89 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Nature communications · 2019
OEOlivier ElementoAVAkanksha VermaCMCem Meydan ASAshley Stephen Doane+1 more →AMAri M. Melnick
PMID: 30778059PMCID: PMC6379396DOI93 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Nature communications · 2019
OEOlivier Elemento ASAshley Stephen Doane CMCem MeydanAVAkanksha Verma+1 more →AMAri M. Melnick
PMID: 30778059PMCID: PMC6379396DOI93 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3.
Cancer research · 2019
OEOlivier ElementoAVAkanksha VermaRWRui WangGGGiorgio Ga. Inghirami
PMID: 30692217DOI37 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors.
Endocrine-related cancer · 2019
OEOlivier ElementoAVAkanksha VermaBMBrendan M. FinnertyMDMaureen D Moore+7 more →TJThomas J Fahey
PMID: 30689542DOI19 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2018
OEOlivier ElementoCGCoryandar GilvaryNSNeel S Madhukar
PMID: 30559168PMCID: PMC7259201DOI52 citations
With Coryandar Gilvary · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
CHL1 expression differentiates Hürthle cell carcinoma from benign Hürthle cell nodules.
Journal of surgical oncology · 2018
OEOlivier ElementoAVAkanksha VermaAAAnna AronovaIMIrene M Min+4 more →TJThomas J Fahey
PMID: 30311656DOI6 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery · 2018
OEOlivier Elemento ASAshley Stephen DoaneWBWendy BéguelinLFLorena Fontán+6 more →AMAri M. Melnick
PMID: 30274972PMCID: PMC6279514DOI161 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Colonoscopic-Guided Pinch Biopsies in Mice as a Useful Model for Evaluating the Roles of Host and Luminal Factors in Colonic Inflammation.
The American journal of pathology · 2018
OEOlivier ElementoAVAkanksha VermaDCDavid C MontroseXKXi Kathy Zhou+1 more →AJAndrew J Dannenberg
PMID: 30273600PMCID: PMC6334259DOI4 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2018
OEOlivier ElementoAVAkanksha Verma
PMID: 30012564DOI54 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer: Secondary Analysis of the NeoALTTO Randomized Clinical Trial.
JAMA oncology · 2018
OEOlivier Elemento DRDavid RedmondJBJose Baselga
PMID: 29902299PMCID: PMC6224305DOI19 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Molecular cell · 2018
OEOlivier ElementoAVAkanksha VermaMRMark R LundquistMDMarcus D GoncalvesJLJared L Johnson+2 more →
PMID: 29727621PMCID: PMC5991623DOI97 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling.
Oncotarget · 2018
OEOlivier ElementoAVAkanksha Verma
PMID: 29552303PMCID: PMC5844739DOI13 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease.
Cancer prevention research (Philadelphia, Pa.) · 2018
OEOlivier ElementoAVAkanksha VermaAGAyca Gucalp XKXi Kathy Zhou+2 more →AJAndrew J Dannenberg
PMID: 29453232PMCID: PMC6290902DOI23 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Analyzing DNA Methylation Patterns During Tumor Evolution.
Methods in molecular biology (Clifton, N.J.) · 2018
OEOlivier ElementoHPHeng Pan
PMID: 29344884PMCID: PMC6545902DOI3 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.
Nature communications · 2018
OEOlivier Elemento DRDavid RedmondMTMatt TeaterZCZhengming ChenJCJayanta Chaudhuri+2 more →
PMID: 29335468PMCID: PMC5768781DOI68 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Publisher Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Nature genetics · 2018
OEOlivier ElementoHPHeng PanNVNipun VermaBPBobbie Pelham-Webb+1 more →DHDanwei Huangfu
PMID: 29255266DOI2 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
Author Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Nature genetics · 2018
OEOlivier ElementoHPHeng PanNVNipun VermaBPBobbie Pelham-Webb+1 more →DHDanwei Huangfu
PMID: 29255265DOI
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.
Stem cell reports · 2017
OEOlivier ElementoAVAkanksha VermaYLYi Liu STStephen T.C. Wong
PMID: 29249663PMCID: PMC5768915DOI53 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Nature genetics · 2017
OEOlivier ElementoHPHeng PanNVNipun VermaBPBobbie Pelham-Webb+1 more →DHDanwei Huangfu
PMID: 29203910PMCID: PMC5742051DOI169 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.
Nature communications · 2017
OEOlivier Elemento DRDavid RedmondWBWendy BéguelinMTMatt Teater+1 more →AMAri M. Melnick
PMID: 29026085PMCID: PMC5638898DOI157 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.
Nature · 2017
OEOlivier ElementoAVAkanksha VermaTHTimothy Hla
PMID: 28538737PMCID: PMC5683179DOI169 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells.
Cell reports · 2017
OEOlivier Elemento ASAshley Stephen DoaneBPBobbie Pelham-WebbDCDafne Campigli Di Giammartino+3 more →EAEftychia Apostolou
PMID: 28514649PMCID: PMC5495017DOI109 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
Nature · 2017
OEOlivier Elemento DRDavid Redmond RLRaphael LisMGMichael G Poulos+9 more →SRShahin Rafii
PMID: 28514438PMCID: PMC5794215DOI178 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
An integrated model for detecting significant chromatin interactions from high-resolution Hi-C data.
Nature communications · 2017
OEOlivier ElementoMCMark CartyMSMerve SahinCSChristina S Leslie
PMID: 28513628PMCID: PMC5442359DOI62 citations
With Mark Carty · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2017
Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.
Cell · 2017
OEOlivier ElementoAVAkanksha Verma
PMID: 28434617PMCID: PMC5510746DOI289 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.
eLife · 2017
OEOlivier ElementoAVAkanksha VermaSCSagar ChhangawalaRMRaul Martinez-McFaline+2 more →YHYariv Houvras
PMID: 28350298PMCID: PMC5389860DOI51 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Melanoma genome evolution across species.
BMC genomics · 2017
OEOlivier ElementoAVAkanksha Verma
PMID: 28173755PMCID: PMC5297047DOI15 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Regulatory elements in molecular networks.
Wiley interdisciplinary reviews. Systems biology and medicine · 2017
OEOlivier Elemento ASAshley Stephen Doane
PMID: 28093886PMCID: PMC5400678DOI31 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2016
OEOlivier ElementoAVAkanksha Verma
PMID: 27993968PMCID: PMC5474138DOI26 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.
Oncotarget · 2016
OEOlivier ElementoHPHeng PanLCLeandro CerchiettiGGGiorgio Ga. Inghirami
PMID: 27793034PMCID: PMC5346742DOI21 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Cancer discovery · 2016
OEOlivier Elemento ASAshley Stephen DoaneHYHsia-Yuan YingKHKaterina Hatzi+5 more →AMAri M. Melnick
PMID: 27733359PMCID: PMC5300005DOI245 citations
With Ashley Stephen Doane, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Cancer discovery · 2016
OEOlivier ElementoDMDylan McNallyHYHsia-Yuan YingKHKaterina Hatzi+5 more →AMAri M. Melnick
PMID: 27733359PMCID: PMC5300005DOI245 citations
With Dylan McNally · Physiology, Biophysics & Systems Biology (PhD) · Class of 2024
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.
Cancer immunology research · 2016
OEOlivier Elemento DRDavid RedmondDBDavid B PageJCJeremy C Durack+11 more →HLHeather L McArthur
PMID: 27587469PMCID: PMC5064839DOI143 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq.
Genome medicine · 2016
OEOlivier Elemento DRDavid RedmondAPAsaf Poran
PMID: 27460926PMCID: PMC4962388DOI112 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.
Diabetes · 2016
OEOlivier ElementoAVAkanksha VermaBPBelen PicatosteJHJoanne H Bruno+1 more →TETimothy E. McGraw
PMID: 27207531PMCID: PMC4878419DOI45 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma.
Journal of visualized experiments : JoVE · 2015
OEOlivier Elemento DRDavid RedmondKNKui NieAMAri M. MelnickWTWayne Tam
PMID: 26780364PMCID: PMC4780861DOI20 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.
Blood · 2015
OEOlivier ElementoAVAkanksha VermaTMTharu M FernandoRMRossella Marullo+4 more →LCLeandro Cerchietti
PMID: 26603836PMCID: PMC4760090DOI77 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.
Leukemia · 2015
OEOlivier Elemento DRDavid RedmondKNK NieYLY Liu+1 more →WTW Tam
PMID: 26530011PMCID: PMC4777778DOI62 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.
Genome medicine · 2015
OEOlivier ElementoAVAkanksha VermaLFLauren FairchildAMAri M. Melnick
PMID: 26521025PMCID: PMC4628784DOI68 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Nature medicine · 2015
OEOlivier ElementoHPHeng PanWTWayne TamAMAri M. MelnickHWHans-Guido Wendel
PMID: 26366710PMCID: PMC4676270DOI390 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
Cell reports · 2015
OEOlivier Elemento DRDavid RedmondMTMatt TeaterNCNyasha ChambweJCJayanta Chaudhuri+2 more →
PMID: 26365193PMCID: PMC4591215DOI101 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.
Science translational medicine · 2015
OEOlivier ElementoAVAkanksha VermaPBPriya BhardwajXKXi Kathy ZhouLTLinda T Vahdat+2 more →
PMID: 26290412PMCID: PMC4837896DOI281 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Epigenomic evolution in diffuse large B-cell lymphomas.
Nature communications · 2015
OEOlivier Elemento DRDavid RedmondHPHeng PanKNKui NieLCLeandro Cerchietti+3 more →
PMID: 25891015PMCID: PMC4411286DOI118 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019
Epigenomic evolution in diffuse large B-cell lymphomas.
Nature communications · 2015
OEOlivier ElementoHPHeng PanDRDavid RedmondKNKui NieLCLeandro Cerchietti+3 more →
PMID: 25891015PMCID: PMC4411286DOI118 citations
With Heng Pan · Physiology, Biophysics & Systems Biology (PhD) · Class of 2018
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Cell · 2015
OEOlivier ElementoAVAkanksha Verma
PMID: 25843629PMCID: PMC6922011DOI293 citations
With Akanksha Verma · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2020
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
Genome biology · 2014
OEOlivier Elemento DRDavid RedmondKNKui NieKWKen W EngPMPeter Martin+2 more →
PMID: 25123191PMCID: PMC4158101DOI92 citations
With David Redmond, PhD · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2019

Postdoc mentee

Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors.
iScience · 2026
OEOlivier Elemento SNShalini Nath SESally Elizabeth ClaridgeBDBenjamin D SteinBDBenjamin David Hopkins
PMID: 41767257PMCID: PMC12937152DOI1 citations
With Shalini Nath · Postdoc mentee
Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival.
Pathology, research and practice · 2025
OEOlivier ElementoJKJunbum KimEPErika Patel BBBhavneet Bhinder+9 more →MAManish A Shah
PMID: 40743578DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.
Cell reports. Medicine · 2025
OEOlivier Elemento SNShalini Nath SESally Elizabeth ClaridgeMAMajd Al AssaadBDBenjamin David Hopkins
PMID: 40628262PMCID: PMC12281429DOI1 citations
With Shalini Nath · Postdoc mentee
The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.
bioRxiv : the preprint server for biology · 2025
OEOlivier ElementoJKJunbum KimJPJiwoon Park EPErika Patel+14 more →CEChristopher E Mason
PMID: 40611896PMCID: PMC12224548DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.
bioRxiv : the preprint server for biology · 2025
OEOlivier ElementoJKJunbum KimHRHiranmayi Ravichandran LYLiron Yoffe BBBhavneet Bhinder+5 more →
PMID: 40027685PMCID: PMC11870609DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.
Clinical and translational medicine · 2025
OEOlivier Elemento SNShalini Nath SESally Elizabeth Claridge ENEda Nur Kozan+1 more →BDBenjamin David Hopkins
PMID: 39856363PMCID: PMC11761363DOI
With Shalini Nath · Postdoc mentee
Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer.
bioRxiv : the preprint server for biology · 2025
OEOlivier ElementoJKJunbum KimLYLiron Yoffe BBBhavneet Bhinder+6 more →VMVivek Mittal
PMID: 39803458PMCID: PMC11722343DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.
bioRxiv : the preprint server for biology · 2025
OEOlivier ElementoJKJ KimHRHiranmayi Ravichandran BDBenjamin David Hopkins ZCZhengming Chen
PMID: 39282294PMCID: PMC11398371DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Integrative Transcriptomic and Single-Cell Protein Characterization of Colorectal Carcinoma Delineates Distinct Tumor Immune Microenvironments Associated with Overall Survival.
Research square · 2024
OEOlivier ElementoJKJunbum KimEPErika Patel BBBhavneet Bhinder+8 more →MAManish A Shah
PMID: 39108491PMCID: PMC11302706DOI
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Nature medicine · 2024
OEOlivier ElementoJKJunbum KimLBLinda Bojmar LSLee Shaashua Berger+23 more →DCDavid C Lyden
PMID: 38942992PMCID: PMC11416063DOI64 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.
Cell · 2023
OEOlivier ElementoJKJunbum KimJCJin-Gyu CheongCPChristopher Parkhurst+23 more →SZSteven Zvi Josefowicz
PMID: 37597510PMCID: PMC10638861DOI243 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma.
Neuro-oncology · 2023
OEOlivier ElementoJKJunbum KimEKEvan K NochMBMelissa Boneta Davis+3 more →LCLewis C Cantley
PMID: 37399061PMCID: PMC10708938DOI33 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study.
The Lancet. Digital health · 2023
OEOlivier ElementoJKJunbum KimJBJosue BarnesMBMatthew Brendel+8 more →IHIman Hajirasouliha
PMID: 36543475PMCID: PMC10193126DOI123 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Spatial omics technologies at multimodal and single cell/subcellular level.
Genome biology · 2022
OEOlivier ElementoJKJunbum KimJPJiwoon Park CMCharles M. Rice CEChristopher E Mason
PMID: 36514162PMCID: PMC9746133DOI113 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19.
medRxiv : the preprint server for health sciences · 2022
OEOlivier ElementoJKJunbum KimRERobert E. Schwartz
PMID: 36482970PMCID: PMC9727772DOI1,117 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging.
Nature methods · 2022
OEOlivier ElementoJKJunbum KimJMJuan Miguel MosqueraRSRenat Shaykhiev
PMID: 36414761DOI1 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
Unsupervised discovery of tissue architecture in multiplexed imaging.
Nature methods · 2022
OEOlivier ElementoJKJunbum KimJMJuan Miguel MosqueraRSRenat Shaykhiev
PMID: 36316562PMCID: PMC11102857DOI67 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024
The spatial landscape of lung pathology during COVID-19 progression.
Nature · 2021
OEOlivier ElementoJKJunbum KimAFAndré F RendeiroCMCem Meydan+4 more →RERobert E. Schwartz
PMID: 33780969PMCID: PMC8204801DOI295 citations
With Junbum Kim · Physiology, Biophysics & Systems Biology · Class of 2024