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Highlights

  1. 1
    Nature communications · 2020
    PMID: 32332823PMCID: PMC7181734DOISenior author67 citations
  2. 2
    Nature communications · 2024
    PMID: 39672812PMCID: PMC11645413DOISenior author12 citations
  3. 3
    The Journal of clinical investigation · 2021
    PMID: 33998599PMCID: PMC8121518DOISenior author37 citations

Publications

138 publications

Active

8 grants
  • MPI
    The role of early oncogenic drivers in maintaining lineage fidelity in prostate cancer
    National Cancer Institute · 2025–2030
    R01CA301637-02
  • PI
    Growth suppressive and oncogenic transcriptional programs controlled by the androgen receptor in prostate cancer
    National Cancer Institute · 2025–2030
    R01CA297829-02
  • MPI
    Upstream and downstream targeting of the SPOP ubiquitin signaling pathway in prostate cancer
    National Cancer Institute · 2024–2029
    R01CA287724-02
  • Co-I
    ESCAPE - Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate Cancer
    National Cancer Institute · 2024–2029
    R37CA282407-01A1
  • KP
    The role of SPOP mutation in opposing lineage plasticity in neuroendocrine prostate cancer
    American Urological Association · 2026–2028
    1614289
  • Co-I
    "Novel Mouse Models for Quantitative Understanding of Baseline and Therapy-Driven Evolution of Prostate Cancer Metastasis"
    National Cancer Institute · 2023–2028
    R01CA272466-01A1
  • Sub-PI
    Quantifying and Personalizing the Clinical Benefit of Metastasis-Directed Therapy in Men with De Novo Oligometastatic Prostate Cancer
    National Cancer Institute · 2021–2027 · via Case Western Reserve University
    5 U01C A257638-04
  • Sub-PI
    Prostate Cancer Foundation subaward for Janny Villa Pulgarin
    Prostate Cancer Foundation · 2023–2027 · via The General Hospital Corporation (dba Massachusetts General Hospital)
    PCF 20YOUN09
Completed grants (18)
  • Sub-PI
    BPTF-mediated gene regulation in prostate cancer
    U.S. Department of Defense · 2022–2025 · via University of Maryland, Baltimore
    No publications yet
    W81XWH2210363
  • MPI
    Immune Microenvironment in Orthotopic Models of Prostate Cancer in Immunocompetent Mice
    Urology Care Foundation · 2024–2025
    UCF 234555-01
  • Co-I
    Characterizing 3'-UTR biology as a mechanism of therapy response in high risk prostate cancer.
    U.S. Department of Defense · 2024–2025
    HT9425-24-1-0310
  • PI
    Collaborative genomic alterations and transcriptional control in prostate cancer
    National Cancer Institute · 2019–2025
    R01CA233650-05
  • PI
    Coordinate Regulation of Oncogenic Signaling Pathways in SPOP Mutant Prostate Cancer
    National Cancer Institute · 2018–2025
    R37CA215040-07
  • Co-I
    Targeting lipid metabolism and diet in patients with locally advanced prostate cancer
    Prostate Cancer Foundation · 2023–2023
    PCF 227920-01
  • Co-I
    G3BP1 Suppresses SPOP Ubiquitin Ligase to Promote Prostate Tumorigenesis
    National Cancer Institute · 2018–2023
    R01CA221152-01A1
  • Co-I
    Weill Cornell Medicine (WCM) SPORE in Prostate Cancer
    National Cancer Institute · 2017–2023
    P50CA211024-05
  • PI
    Addgene 705468
    Addgene, Inc. · 2022–2023
    Addgene 705468
  • PI
    Addgene 703836
    Addgene, Inc. · 2022–2023
    Addgene 703836
  • PI
    Defining the Potential of Early Molecular Subtypes of Prostate Cancer to Progress to AR-Indifferent Disease
    U.S. Department of Defense · 2019–2022
    W81XWH-19-1-0403
  • PI
    Subtype-specific modes of clinical and molecular progression in prostate cancer
    Damon Runyon Cancer Research Foundation · 2019–2022
    88C-16
  • KP
    The Role of CHD1 Loss on Cistrome Reprogramming and Prostate Cancer Progression
    Prostate Cancer Foundation · 2017–2021
    PCF 17091418-01
  • PI
    Coordinated Roles of SPOP Mutation and CHD1 Deletion in Prostate Cancer Pathogenesis
    U.S. Department of Defense · 2017–2019Fellowship
    W81XWH-17-1-0385
  • MPI
    Repurposing drugs for prostatic disease, a high-throughput imaging based approach
    American Urological Association · 2018–2019
    UCF 180747-01
  • PI
    Presurgical Trials to Target Distinct Subclasses of Localized Prostate Cancer
    Damon Runyon Cancer Research Foundation · 2016–2019
    88-16
  • PI
    Genomic Instability and DNA Repair in a Distinct Molecular Class of Prostate Cancer
    National Cancer Institute · 2014–2019Career
    K08CA187417-05
  • PI
    Targeting Genomic Instability in SPOP Mutant Prostate Cancer.
    Prostate Cancer Foundation · 2014–2017
    PCF 15060870-03 EWOF

Honors & distinctions

2 honors
  • Member · American Society for Clinical Investigation · 2020
  • Damon Runyon Fellowship / Grant · Damon Runyon Cancer Research Foundation · 2016

Available technologies

News mentions

External relationships

Advisory/Scientific Board Member

American Urological Association

Professional Services

American Urological Association

Other Interest

National Cancer Institute · United States Department of Defense

Other

Pfizer, Inc.