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Highlights

  1. 1
    Blood cancer discovery · 2023
    PMID: 36723991PMCID: PMC10150291DOISenior author56 citations
  2. 2
    Blood · 2020
    PMID: 32157281PMCID: PMC7243148DOISenior author56 citations
  3. 3
    Blood advances · 2020
    PMID: 33104794PMCID: PMC7594393DOISenior author44 citations

Publications

75 publications

Active

15 grants
  • MPI
    B cell determinants of EBV latency
    National Cancer Institute · 2022–2027
    U01CA275301-05
  • KP
    Biomarkers of response in primary mediastinal B-cell lymphoma: Defining tumor microenvironment signatures
    Hyundai Hope on Wheels Foundation · 2024–2026
    HHWF 240412-01
  • KP
    Targeting latency switch for the treatment of EBV-associated lymphomas
    American Cancer Society · 2024–2026
    PF-23-1143526-01-IBCD
  • Sub-PI
    Assessment of Clonal Hematopoiesis and Its Relationship to Cardiovascular Disease in Hodgkin Lymphoma Survivors
    U.S. Department of Defense · 2022–2026 · via Washington University, The
    W81XWH-22-1-0665
  • MPI
    Sensitizing Latency I EBV Lymphomas to Cytotoxic T Lymphocyte Therapy
    American Society of Hematology Inc · 2025–2026
    ASH 250160-01
  • KP
    Sensitizing Latency I EBV Lymphomas to Cytotoxic T Lymphocyte Therapy
    Lymphoma Research Foundation · 2025–2026
    LRF 244461-01
  • Sub-PI
    An Integrative Radiogenomic Framework for Predicting Treatment Failure in Adolescents & Young Adults with Hodgkin Lymphoma
    U.S. Department of Defense · 2022–2026 · via Emory University
    W81XWH-22-1-0338
  • MPI
    Targeting CD30 to enhance response to immune checkpoint blockade in Hodgkin Lymphoma
    National Cancer Institute · 2022–2026 · via Children's Oncology Group· 3 renewals
    UG1CA233249-06
  • Sub-PI
    A pilot study to evaluate ctDNA in PMBCL
    National Cancer Institute · 2025–2026 · via Children's Oncology Group
    5 UG1 CA233249- 06
  • Sub-PI
    COG Hodgkin Lymphoma (Defining Biomarkers of Response to Immunotherapy in Pediatric Hodgkin Lymphoma - The Jeffrey Pride Foundation Integrated Correlative Biology Awards)
    Jeffrey Pride Foundation INC · 2024–2026 · via Children's Oncology Group
    NY018_2024_01_ROTH
  • Sub-PI
    Evaluating Biologic Mechanisms of Racial and Ethnic Disparities in Pediatric Hodgkin Lymphoma
    National Cancer Institute · 2024–2026 · via Children's Oncology Group
    5 UG1 CA233249- 06
  • Sub-PI
    Overcoming resistance to PD-1 Blockade in Hodgkin Lymphoma
    National Cancer Institute · 2024–2026 · via Children's Oncology Group
    5 UG1 CA233249- 06
  • PI
    Targeting Latency Switch in EBV+ Lymphomas
    National Cancer Institute · 2022–2026
    R37CA262517-04
  • MPI
    Risk Stratification using Tumor Microenviroment Signatures in Hodgkin Lymphoma
    Children's Oncology Group · 2022–2026
    COG 222649-02
  • MPI
    COG U10CA180886 PO: 0000004866
    National Cancer Institute · 2020–2026 · via Public Health Institute· 3 renewals
    U10CA180886-11
Completed grants (13)
  • PI
    Biomarkers Predictive of Antitumor Response in Primary Mediastinal B-cell Lymphoma
    Children's Oncology Group · 2022–2025
    COG 222665-01
  • Sub-PI
    AHO1822 Study Chair
    Merck & Co., Inc. · 2020–2025 · via The Children’s Hospital of PhiladelphiaContract
    SA 203887-01
  • Sub-PI
    Genomic and Immunologic Predictors of Response in Primary Mediastinal B-cell Lymphoma - The Jeffrey Pride Foundation Integrated Correlative Biology Awards
    Jeffrey Pride Foundation INC · 2024–2025 · via Children's Oncology Group
    NY018_2024_02_ROTH
  • PI
    Defining the evolution and tumor microenvironment interactions of classic Hodgkin lymphoma through single-cell multi-omics and genetically engineered mouse models
    Starr Cancer Consortium · 2022–2024
    SCC I15-0016
  • PI
    Targeting latent viral antigens in EBV+ Burkitt Lymphoma
    Hyundai Hope on Wheels Foundation · 2021–2024
    HHWF 215201-02
  • PI
    Modulation Of Viral Latency In EBV+ Lymphomas To Sensitize Tumors To Immunotherapy
    American Society of Hematology Inc · 2021–2023
    ASH 210413-02
  • PI
    Rational Translation of EZH2 Targeted Therapy in Germinal Center B-Cell Lymphoma
    National Cancer Institute · 2017–2021Career
    K08CA219473-04
  • PI
    Why Personalized Medicine Fails: Shifting Focus to Genotype the Rare Cancer-initiating Cell in Hodgkin Lymphoma
    The Hartwell Foundation · 2019–2021
    THF 190511-01
  • PI
    Modulation of Viral Latency in EBV-Associated Lymphomas as a Mechanism to Sensitize Tumors to EBV-Directed Cellular Therapy
    Starr Cancer Consortium · 2018–2020
    I11-0043
  • PI
    Whole exome and RNA sequencing of Hodgkin Reed-Sternberg cells isolated from pediatric Hodgkin lymphoma cases across COG sites
    Children's Oncology Group · 2019–2019
    COG 191520-01
  • PI
    Targeting the Hsp90 Oncoproteome in Pediatric Burkitt Lymphoma
    St. Baldrick's Foundation · 2015–2018
    SBF 170821-03
  • MPI
    AMC Fellowship Program
    National Cancer Institute · 2014–2015 · via University of California, Los Angeles
    U01CA121947-04 EW
  • MPI
    Genomic Biomarker Discovery in AIDS-Related Burkitt Lymphoma
    National Cancer Institute · 2014–2015 · via Sloan-Kettering Institute for Cancer Research
    P30CA008748-49 EW

Honors & distinctions

1 honor
  • Member · American Society for Clinical Investigation · 2023

Clinical research

4 studies

Active

2 studies
  • PI
    Body Mass Index and the Development of Subsequent Malignant Neoplasms among Adolescent and Young Adult Cancer Survivors
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)
  • PI
    Retrospective multi-center study evaluating the benefit of consolidation with brentuximab vedotin following autologous stem cell transplant in pediatric patients with relapsed/refractory Hodgkin lymphoma
    Memorial Sloan Kettering Cancer Center · OPEN TO ACCRUAL (as of 2021)
Completed & closed trials (2)
  • PI
    CITY OF HOPE: A multicenter retrospective study of pediatric patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
    City of Hope National Medical Center · CLOSED TO ACCRUAL (as of 2025)
  • PI
    An Open-label, Uncontrolled, Multicenter Phase II Trial of MK-3475 (Pembrolizumab) in Children and Young Adults With Newly Diagnosed Classical Hodgkin Lymphoma With Inadequate (Slow Early) Response to Frontline Chemotherapy (KEYNOTE 667)
    PHASE2 · Children's Oncology Group · IRB STUDY CLOSURE (as of 2023)
    Hodgkin Lymphoma
    NCT03407144

Available technologies

News mentions

External relationships

Other Interest

Gerson Lehrman Group (GLG) · Guidepoint Global LLC · Roche Pharmaceuticals, Inc. · Rosenblum Newfield, LLC

Other

Roche Pharmaceuticals, Inc.