RecruitingObservationalNCT06388421 ↗DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)Robert J. KanerPIInterventionOther: Prospective study assessmentsDatesJan 2025 – Sep 2030 (est.)
RecruitingObservationalNCT06401421 ↗EXActDNA-003 / NSABP B-64: Breast Cancer Clinical Validation Study to Predict Recurrence of High-Risk Early Breast Cancer Treated With Neoadjuvant Therapy Using a Bespoke Circulating Tumor DNA Assay to Detect Molecular Residual DiseaseEleni AndreopoulouPIInterventionDiagnostic test: ctDNA MRD testDatesJun 2024 – Apr 2030 (est.)SponsorExact Sciences CorporationBreast Cancer
RecruitingObservationalNCT06424327 ↗Pulmonary Segmentectomy for Lung Cancer: A Real-World International Registry-TSOG 108Nasser K AltorkiPIInterventionOther: Patient-Reported Outcomes Measurement Information SystemDatesMay 2024 – May 2029 (est.)SponsorMemorial Sloan Kettering Cancer CenterLung CancerLung Cancer Stage I
Active, not recruitingObservationalNCT06431815 ↗Prospective, Multi-site Safety and Effectiveness Post-Approval Study of FARAPULSE Pulsed Field Ablation in Paroxysmal Atrial FibrillationDavid J SlotwinerPIInterventionDevice: FARAPULSE™ Pulsed Field Ablation SystemDatesSep 2024 – Oct 2028 (est.)SponsorBoston Scientific CorporationParoxysmal Atrial Fibrillation
RecruitingObservationalNCT06486454 ↗Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)Juan Pablo RoccaPIInterventionDevice: HistoSonics Edison SystemDatesOct 2024 – Nov 2034 (est.)SponsorHistoSonics INCLiver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
RecruitingObservationalNCT06647511 ↗Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee WomenGunisha KaurPIInterventionDevice: Nokia-Withings BPM Connect Blood Pressure Monitor · Device: Smartwatch DevicesDatesSep 2024 – Sep 2028 (est.)SponsorWeill Medical College of Cornell UniversityGestational Hypertension
Active, not recruitingObservationalNCT06693531 ↗A U.S. Registry of Eosinophilic Esophagitis Patients Treated With DUPIXENT® As Standard of CareAliza B SolomonPIInterventionDrug: dupilumabDatesNov 2024 – May 2030 (est.)SponsorRegeneron Pharmaceuticals, Inc.Eosinophilic Esophagitis (EoE)
RecruitingObservationalNCT06766006 ↗A Multicentric Left Ventricular Venting Strategy Comparison in Patients Receiving Venoarterial Extracorporeal Life SupportBerhane M. WorkuPIInterventionProcedure: Venoarterial extracorporeal life support (VA ECLS) implantDatesApr 2024 – Apr 2026 (est.)SponsorMaastricht University Medical Centre,Shock, CardiogenicCardiac ArrestExtracorporeal Membrane Oxygenation Complication
RecruitingObservationalNCT06892041 ↗Development of RPBM for Quantitative Assessment of Myofascial PainGene KimPIDatesSep 2025 – Jul 2026 (est.)SponsorWeill Medical College of Cornell UniversityMasticatory Myofascial Pain Syndrome
RecruitingObservationalNCT07021742 ↗BioHealx® Anal Fistula Device Post Market Surveillance StudyLea Channah LowenfeldPIInterventionDevice: BioHealxDatesJun 2025 – Oct 2026 (est.)SponsorSignum Surgical USA INCFistula-in-ano
RecruitingObservationalNCT07098858 ↗The WiSE®-UP Study (The WiSE System Utilization & Performance Study)James E. IpPIInterventionDevice: The Wise SystemDatesNov 2025 – Sep 2032 (est.)SponsorEBR Systems, IncHeart Failure
Active, not recruitingObservationalNCT07111663 ↗An Observational Study of Individuals With Isolated DystoniaHarini SarvaPIDatesJun 2025 – Oct 2026 (est.)SponsorVima Therapeutics INCIsolated/Primary Dystonia That Affects More Than One Region of the Body
RecruitingObservationalNCT07198113 ↗Clinical Outcomes of Medications Post Anti-TNF: Researching Effectiveness in Pediatric IBDRobbyn SockolowPIDatesNov 2025 – Sep 2028 (est.)SponsorUniversity of North Carolina at Chapel HillUlcerative Colitis, PediatricInflammatory Bowel DiseasesCrohn Disease
RecruitingObservationalNCT07243002 ↗Real-world Evaluation of Patient Outcomes and Experiences With Ribociclib Early Adopters: A Hybrid Study With Prospective Patient-reported Outcomes and Retrospective Clinical Chart Review.Pooja MurthyPIDatesDec 2025 – Apr 2030 (est.)SponsorNovartis Pharma AGBreast Cancer
CompletedObservationalNCT00898365 ↗Renal Tumors Classification, Biology, and Banking StudyAlexander Ja-Ho ChouPIInterventionOther: Cytology Specimen Collection Procedure · Other: Laboratory Biomarker AnalysisDatesFeb 2006 – Mar 2026SponsorChildren's Oncology GroupAdult Cystic NephromaAnaplastic Kidney Wilms TumorAngiolipoma+22 more
CompletedObservationalNCT01751841 ↗Outcome Analysis for Minimally Invasive Spine Surgery and NavigationRoger HartlPIDatesMay 2012 – Oct 2023SponsorWeill Medical College of Cornell UniversityDegenerative Disc Disease
CompletedObservationalNCT02161068 ↗Chart Review/PKD GenotypingJon David BlumenfeldPIDatesDec 2013 – Nov 2021SponsorRogosin Institute, Inc.ADPKD
CompletedObservationalNCT02379104 ↗ROTEM® Sigma Performance Evaluation - Method Comparison With Predicate Device and Reference IntervalsHugh C HemmingsPIInterventionDevice: ROTEM sigmaDatesOct 2017 – Oct 2018 (est.)SponsorInstrumentation LaboratoryBlood Coagulation Disorders
CompletedObservationalNCT03326076 ↗Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure RegistryDarshana M DadhaniaPIInterventionDiagnostic test: Donor-derived cell-free DNA (AlloSure®) · Other: Standard care · Diagnostic test: Peripheral blood gene expression profiling (AlloMap Kidney) · Diagnostic test: Analytic platform (IBox)DatesJan 2018 – Jun 2025 (est.)SponsorCareDx, Inc.Kidney Transplant Rejection
CompletedObservationalNCT03619863 ↗A Natural History Cohort Study of the Safety, Effectiveness, and Practice of Treatment for People With HemophiliaCatherine McGuinnPIDatesOct 2018 – May 2023SponsorAmerican Thrombosis & Hemostasis Network, Inc.Hemophilia A With InhibitorHaemophilia A Without InhibitorHemophilia B With Inhibitor+1 more