Highlights
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Publications
178 publications
Funding
42 grantsView NIH portfolio on RePORTER ↗
Active
17 grants- Sub-PI75N92025D00023SubPopulations and InteRmediate Outcomes In COPD (SPIROMICS) IIINational Heart, Lung, and Blood Institute · 2024–2031 · via The Regents of the University of California, San Francisco
- Sub-PIALA 255388-01Lung Health Cohort" (ALA-LHC) Study - SupplementBoehringer Ingelheim · 2025–2029 · via American Lung Association, Incorporated
- MPIT32HL134629-06A1Multidisciplinary Approach Training in Respiratory ResearchNational Heart, Lung, and Blood Institute · 2018–2028· 3 renewals
- Co-IR61HL169190-01A1Gene Therapy for Alpha 1-Antitrypsin DeficiencyNational Heart, Lung, and Blood Institute · 2024–2028
- Co-IUG3AG098024-01Gene Therapy for APOE4 Homozygous Alzheimer's DiseaseNational Institute on Aging · 2026–2028
- PIALA 243872-03ALA-ACRCAmerican Lung Association, Incorporated · 2024–2027
- PIALA 244212-01Lung Health Cohort" (ALA-LHC) StudyAmerican Lung Association, Incorporated · 2024–2027
- KPUL1TR002384-06Clinical and Translational Science Center - UL1National Center for Advancing Translational Sciences · 2022–2027
- MPIR01HL166983-01A1Ancillary SOURCE Study: Characterization of Small Airway Basal Cell Biology in Early COPDNational Heart, Lung, and Blood Institute · 2023–2027
- Sub-PIR01HL144718-06Understanding the Origins of Early COPDNational Heart, Lung, and Blood Institute · 2020–2027 · via University of Massachusetts Medical School· 2 renewals
- PICOPD 251305- 01Study Agreement between Weill Cornell and COPD Foundation - SOURCECOPD Foundation, Inc. · 2024–2027
- Co-IP01HL114501-10Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette SmokersNational Heart, Lung, and Blood Institute · 2021–2027
- MPIU24HL145265-04Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyNational Heart, Lung, and Blood Institute · 2021–2027 · via The Regents of the University of Michigan
- Sub-PIU24HL154946-042/2 Doxycycline for Emphysema in People Living with HIV: The DEPTH TrialNational Heart, Lung, and Blood Institute · 2024–2026 · via The Regents of the University of Michigan
- PIUH3HL154944-041/2 Doxycycline for Emphysema in People Living with HIV: The DEPTH TrialNational Heart, Lung, and Blood Institute · 2021–2026
- Co-ISF 221362-03Development of a Stakeholder Engaged Intervention to Improve Knowledge and Health-Related Quality of Life in SSc-ILDScleroderma Foundation · 2022–2026
- PIALA 255262-01American Lung Association-Airways Clinical Research Center -COPD-OMA (ALA-COPD-OMA) StudyAmerican Lung Association, Incorporated · 2025–2026
Completed grants (25)
- PICOPD 234696-02Study Agreement between Weill Cornell and COPD Foundation - SPRIOMICSCOPD Foundation, Inc. · 2023–2025
- Sub-PIALA CU20-2308ACRC New York ConsortiumAmerican Lung Association, Incorporated · 2016–2024 · via Columbia University
- Co-IR33HL158540-02Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsNational Heart, Lung, and Blood Institute · 2022–2024
- Sub-PIP20NR018072-05Center for Improving Palliative Care for Vulnerable Adults with MCC (CIPC)National Institute of Nursing Research · 2021–2024 · via Columbia University
- Co-IU01HL137880-05SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionNational Heart, Lung, and Blood Institute · 2017–2024 · via University of California, San Francisco
- Co-IR01AI148416-03S2Epigenetic alterations and phenotypes in innate immune cells and their progenitors in PASCNational Institute of Allergy and Infectious Diseases · 2022–2023
- Sub-PIW81XWH-15-1-0705Beta-Blockers for the Prevention of Acute Exacerbations of COPDU.S. Department of Defense · 2015–2023 · via University of Alabama-Birmingham
- Sub-PIALA CU20-2308ALA- Airways Clinical Research Centers (ACRC) network: Losartan Effects on Emphysema Progression Trial (LEEP) TrialAmerican Lung Association, Incorporated · 2017–2023 · via Columbia University
- Co-IR01HL134163-03In Vivo Biomarker that Identifies Waterpipe Smoking-Related Lung HealthNational Heart, Lung, and Blood Institute · 2016–2021
- PICOPD 190316-03Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)-RETHINCCOPD Foundation, Inc. · 2018–2021
- Sub-PIU01HL128954-05(RETHINC) - Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)National Heart, Lung, and Blood Institute · 2016–2021 · via COPD Foundation, Inc.· 2 renewals
- Sub-PIALA CU19ALA- Airways Clinical Research Centers (ACRC) network - COCOAmerican Lung Association, Incorporated · 2018–2021 · via Columbia University
- KPR01HL134549-03HIV Reprogrammed Airway Basal Cells Acquire a “Tissue Destructive” PhenotypeNational Heart, Lung, and Blood Institute · 2016–2021
- KPCRYSTAL15XX0EWOFAssessment and Gene Repair of Human CF Airway Basal Stem/Progenitor CellsCystic Fibrosis Foundation · 2016–2020
- Co-IU01HL121828-05HIV+ Alveolar Macrophage Oxidant-Mediated Apoptosis of Pulmonary EndotheliumNational Heart, Lung, and Blood Institute · 2013–2019
- Sub-PIR01HL122438-04S1Parametric Response Mapping in COPDNational Heart, Lung, and Blood Institute · 2014–2019 · via The Regents of the University of Michigan· 2 renewals
- KPR56DE026027-03Biology of the Oral Epithelium of E-Cigarette SmokersNational Institute of Dental and Craniofacial Research · 2016–2019
- Co-IR01HL118857-05HIV-Related Accelerated Aging of the Airway EpitheliumNational Heart, Lung, and Blood Institute · 2013–2019
- PIR34HL117352-02 EWDoxycycline for COPD in HIV-Infected PatientsNational Heart, Lung, and Blood Institute · 2012–2017
- PIHHSN268200900017C EWSubpopulation and Intermediate Outcome Measure in COPD Study SPIROMICS: Clinical CenterNational Heart, Lung, and Blood Institute · 2009–2016
- KPR01NS061848-04 EWGene Therapy for Batten Disease Using AAVrh.10 Expressing Human CLN2 cDNANational Institute of Neurological Disorders and Stroke · 2010–2016
- PIU10HL080383-05Idiopathic Pulmonary Fibrosis Clinical Research NetworkNHLBI · 2005–2012 · via NIH RePORTER
- MPIP50HL084936-05Role of Alveolar Macrophages in the Accelerated Emphysema of HIV-1 PositiveNHLBI · 2006–2011 · via NIH RePORTER
- PIR01HL062259-04Vascular endothelial growth factor induced lung edemaNHLBI · 2001–2005 · via NIH RePORTER
Clinical research
27 studies
Active
6 studies- PINCT07036523A Double-blind, Randomised, Placebo-controlled, Parallel Group, Phase IIa Trial to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of BI 765423 Administered Intravenously With or Without Standard of Care in Patients With Idiopathic Pulmonary FibrosisPHASE2 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · OPEN TO ACCRUAL (as of 2026)Idiopathic Pulmonary Fibrosis
- PIIndividual Patient Expanded Access Investigational New Drug Application (IND), ALT-100, SIND#Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
- PINCT06388421DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)United Therapeutics · OPEN TO ACCRUAL (as of 2026)Pulmonary Hypertension Due to Lung Diseases and Hypoxia; Pulmonary Hypertension; Interstitial Lung Disease
- PISubPopulations and InteRmediate Outcome Measures In COPD Study SPIROMICS IIIUniversity of California, San Francisco · OPEN TO ACCRUAL (as of 2025)
- PINCT06238622An Open-label Extension Trial of the Long-term Safety and Efficacy of BI 1015550 Taken Orally in Patients With Idiopathic Pulmonary Fibrosis (IPF) and Progressive Pulmonary Fibrosis (PPF) (FIBRONEER™-ON)PHASE3 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · OPEN TO ACCRUAL (as of 2024)Idiopathic Pulmonary Fibrosis; Progressive Pulmonary Fibrosis
- PINCT04543461The American Lung Association (ALA) Lung Health CohortThe Johns Hopkins University · OPEN TO ACCRUAL (as of 2024)Lung Diseases
Completed & closed trials (21)
- PIIs there a need for gender specific adapted therapy in the treatment of COPD?Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2025)
- PINCT05321069A Double Blind, Randomized, Placebo-controlled Trial Evaluating the Efficacy and Safety of BI 1015550 Over at Least 52 Weeks in Patients With Idiopathic Pulmonary Fibrosis (IPF)PHASE3 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · IRB STUDY CLOSURE (as of 2025)Idiopathic Pulmonary Fibrosis
- PINCT05382208Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)PHASE2 · Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2025)Emphysema; HIV
- PINCT05321082A Double Blind, Randomized, Placebo-controlled Trial Evaluating the Efficacy and Safety of BI 1015550 Over at Least 52 Weeks in Patients With Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs)PHASE3 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · IRB STUDY CLOSURE (as of 2025)Lung Diseases, Interstitial
- PINCT04636814A 52-week, Randomized, Double-blind, Double-dummy, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg), Parallel Group, Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI add-on to Maintenance Triple Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis.PHASE3 · Chiesi Farmaceutici S.p.A. · IRB STUDY CLOSURE (as of 2025)Chronic Obstructive Pulmonary Disease
- PINCT04930666The Development and Pilot Testing of a Brief Shared Decision-Making Intervention to Improve Palliative Care Outcomes for Adults With Advanced Lung DiseaseColumbia University Medical Center · CLOSED TO ACCRUAL (as of 2024)Pulmonary Disease, Chronic Obstructive; Lung Diseases, Interstitial
- PITOLLIP single nucleotide polymorphism and treatment effect in IPFWeill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2024)
- PIMitochondrial dysfunction as a hallmark of interstitial lung diseaseWeill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2024)
- PINCT05033990SPIROMICS Study of Early COPD Progression (SOURCE)Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2024)COPD, Early-Onset
- PINCT05130970A Randomized, Double-blind, Placebo-controlled, Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of Garadacimab in Subjects With Idiopathic Pulmonary FibrosisPHASE2 · CSL Behring GmbH · IRB STUDY CLOSURE (as of 2024)Idiopathic Pulmonary Fibrosis
- PIAn Observational Study of Beta-Blocker Use in Patients with Chronic Obstructive Pulmonary Disease (COPD) and Acute Myocardial InfarctionUniversity of Alabama-Birmingham · IRB STUDY CLOSURE (as of 2023)
- PIA multi-center, real-world exploratory cohort study to evaluate cough frequency, severity, and impact on quality of life in patients with non-idiopathic pulmonary fibrosis interstitial lung diseaseBoehringer Ingelheim Pharmaceuticals, Inc. (USA) · IRB STUDY CLOSURE (as of 2023)
- PINCT03267108A Randomized, Double-Blind, Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects at Risk of Pulmonary Hypertension Associated With Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2) - REBUILDPHASE3 · Bellerophon Pulse Technologies LLC · IRB STUDY CLOSURE (as of 2023)Pulmonary Fibrosis; Pulmonary Hypertension
- PINCT03727802TRK-250 - A Phase I, Double-Blind, Placebo-Controlled, Single and Multiple Inhaled Dose, Safety, Tolerability, and Pharmacokinetic Study of TRK-250 in Subjects With Idiopathic Pulmonary FibrosisPHASE1 · Toray Industries · IRB STUDY CLOSURE (as of 2022)Idiopathic Pulmonary Fibrosis
- PINCT03820726An Open-label Extension Trial of the Long Term Safety of Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)PHASE3 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · IRB STUDY CLOSURE (as of 2022)Lung Diseases, Interstitial
- PINCT05074875Post COVID-19 Hypoxemic Respiratory Failure Residual Pathophysiologic OutcomesWeill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2022)Covid19
- PIIndividual Patient Expanded Access of REGEN-COV Investigational New Drug Application (sIND) #157001Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2022)
- PIIndividual Patient Expanded Access Investigational New Drug Application (IND), Clofazimine. sIND#147574Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2022)
- PIRandomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study with Inhaled RVT-1601 for the Treatment of Persistent Cough in Patients with Idiopathic Pulmonary Fibrosis (IPF): SCENIC TrialRespivant Sciences, Inc · IRB STUDY CLOSURE (as of 2020)
- PIIndividual Patient Expanded Access Investigational New Drug Application (IND), Clofazimine. sIND # 146693Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2020)
- PINCT03717012Study of Pulmonary Rehabilitation In Nintedanib Treated Patients With IPF: Improvements in Activity, Exercise Endurance Time, and QoLPHASE4 · Boehringer Ingelheim Pharmaceuticals, Inc. (USA) · IRB STUDY CLOSURE (as of 2020)Idiopathic Pulmonary Fibrosis
News mentions
1 mentionView all WCM news ↗
- NIH Grant Funds Antibiotic Trial for Patients with HIV and EmphysemaDecember 13, 2022
Weill Cornell Medicine has been awarded a five-year, $7.8 million grant from the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, to study whether the antibiotic doxycycline may slow the progression of the chronic lung disease emphysema in people living with well-controlled HIV.
Mentoring
1 mentee
External relationships
Ownership
Doximity, Inc.
Professional Services
Avalyn Pharma, Inc. · PLIANT THERAPEUTICS INC. · PureTech Health · UpToDate, Inc.
Proprietary Interest
UpToDate, Inc.
Other Interest
Boehringer Ingelheim Ltd · GlaxoSmithKline
Other
Boehringer Ingelheim Ltd · GlaxoSmithKline · Pfizer, Inc.