Overview
Pilot Study for the Safe Use of Secretin on Autistic Children, 1998-2000
Publications
Funding
Completed grants (1)
- PIICN SRA 222376Real-world Evidence for the Effectiveness and Safety of Ustekinumab Treatment in Children with Crohn's Disease: A Retrospective Cohort Study using the ImproveCareNow Registry DataImproveCareNow Inc. · 2022–2022Contract
Clinical research
Active
3 studies- PINCT07198113Clinical Outcomes of Medications Post Anti-TNF: Researching Effectiveness in Pediatric IBDUniversity of North Carolina at Chapel Hill · OPEN TO ACCRUAL (as of 2026)Ulcerative Colitis, Pediatric; Inflammatory Bowel Diseases; Crohn Disease
- PIPrecision Medicine in Pediatric Inflammatory Bowel Disease CareWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
- PIDeveloping and validating a predictive model for the treatment of iron deficiency anemia in pediatric Crohnâ s disease through analysis of microbiome and patient laboratory dataWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2023)
Completed & closed trials (3)
- PINCT04624230OPEN-LABEL INDUCTION AND MAINTENANCE STUDY OF ORAL CP-690,550 (TOFACITINIB) IN CHILDREN WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITISPHASE3 · Pfizer, Inc. · IRB STUDY CLOSURE (as of 2025)Ulcerative Colitis
- PIReal-world Evidence for the Effectiveness and Safety of Ustekinumab Treatment in Children with Crohn's Disease: A Retrospective Cohort Study using the ImproveCareNow Registry DataCincinnati Childrenâs Hospital Medical Center · IRB STUDY CLOSURE (as of 2023)
- PIPrometheus - 18IBD01 - Biomarkers Detection in Crohn's DiseasePrometheus Laboratories, Inc. · IRB STUDY CLOSURE (as of 2022)
News mentions
- Putting the Brakes on Chronic InflammationJune 12, 2024
Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals—a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).
- Discovery Reveals How the Immune System Tolerates Friendly Gut BacteriaSeptember 7, 2022
Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill Cornell Medicine.
- Scientists Identify a Key Molecular Protector of Gut HealthJuly 13, 2022
A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.
- Immune Cells Heal the Intestine by Controlling IronApril 14, 2020
An iron-regulating molecule called hepcidin is produced by the immune system and restricts the growth of gut bacteria after an intestinal injury, helping to heal the lining of the intestine, according to a study by Weill Cornell Medicine, NewYork-Presbyterian and Institut Cochin investigators.
- Researchers Discover New Pathway Regulating Intestinal Health that is Impaired in Children with IBDApril 3, 2019
Production of an essential protein for maintaining a healthy immune response in the intestine called interleukin-2 (IL-2) depends on immune cells known as innate lymphoid cells (ILCs), according to a study by Weill Cornell Medicine researchers.