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Scholars/Anna G Orr, PhD/Co-authored with mentees

Co-authored publications with mentees

Anna G Orr, PhD · 12 publications across 9 mentees

MD-PhD mentee

Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease · 2025
AGAnna G OrrCZConstance ZhouEHEvelyn HardinTSTill S ZimmerSJStephanie Jackvony+2 more →
PMID: 40339618PMCID: PMC12240875DOI3 citations
With Constance Zhou · MD-PhD WGS Neuroscience (MD-PhD)
Hippocampal astrocytes induce sex-dimorphic effects on memory.
Cell reports · 2024
AGAnna G OrrCZConstance ZhouMWMinwoo Wendy JangDBDaniel BarnettTSTill S Zimmer+2 more →
PMID: 38795347PMCID: PMC11234507DOI22 citations
With Constance Zhou · MD-PhD WGS Neuroscience (MD-PhD)
Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
Science advances · 2023
AGAnna G OrrCZConstance ZhouSMSamantha M MeadowsSJStephanie JackvonyRERobert E. Schwartz+1 more →
PMID: 37075107PMCID: PMC10115456DOI40 citations
With Constance Zhou · MD-PhD WGS Neuroscience (MD-PhD)

PhD mentee

ALS/FTD-linked TDP-43 alterations prevent HSV-1 infection by disrupting cell-adhesion pathways.
bioRxiv : the preprint server for biology · 2026
PMID: 42856515PMCID: PMC13648640DOI
With Laraib Ijaz · Neuroscience (PhD)
Distinct sources and effects of mitochondrial reactive oxygen species.
Molecular cell · 2026
AGAnna G OrrDBDaniel BarnettCBCaroline BooraemAOAdam Orr
PMID: 42497856DOI
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Distinct sources and effects of mitochondrial reactive oxygen species.
Molecular cell · 2026
AGAnna G OrrCBCaroline BooraemDBDaniel BarnettAOAdam Orr
PMID: 42497856DOI
With Caroline Booraem · Neuroscience (PhD)
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Nature metabolism · 2025
AGAnna G OrrDBDaniel BarnettTSTill S ZimmerCBCaroline Booraem+3 more →AOAdam Orr
PMID: 41188644PMCID: PMC12616538DOI27 citations
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Nature metabolism · 2025
AGAnna G OrrSMSamantha M MeadowsDBDaniel BarnettTSTill S Zimmer+3 more →AOAdam Orr
PMID: 41188644PMCID: PMC12616538DOI27 citations
With Samantha Meadows · Neuroscience (PhD) · Class of 2023
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Nature metabolism · 2025
AGAnna G OrrCBCaroline BooraemDBDaniel BarnettTSTill S Zimmer+3 more →AOAdam Orr
PMID: 41188644PMCID: PMC12616538DOI27 citations
With Caroline Booraem · Neuroscience (PhD)
Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease · 2025
AGAnna G OrrDBDaniel BarnettCZConstance ZhouEHEvelyn HardinTSTill S Zimmer+2 more →
PMID: 40339618PMCID: PMC12240875DOI3 citations
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease · 2025
AGAnna G OrrSJStephanie JackvonyCZConstance ZhouEHEvelyn HardinTSTill S Zimmer+2 more →
PMID: 40339618PMCID: PMC12240875DOI3 citations
With Stephanie Jackvony · Neuroscience (PhD) · Class of 2025
Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease · 2025
AGAnna G OrrEHEvelyn HardinCZConstance ZhouTSTill S ZimmerSJStephanie Jackvony+2 more →
PMID: 40339618PMCID: PMC12240875DOI3 citations
With Evelyn Hardin · Neuroscience (PhD)
Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
AGAnna G OrrSJStephanie Jackvony
PMID: 39692624PMCID: PMC11772715DOI5 citations
With Stephanie Jackvony · Neuroscience (PhD) · Class of 2025
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
bioRxiv : the preprint server for biology · 2024
AGAnna G OrrDBDaniel BarnettTSTill S ZimmerCBCaroline BooraemAOAdam Orr
PMID: 39229090PMCID: PMC11370371DOI
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
bioRxiv : the preprint server for biology · 2024
AGAnna G OrrCBCaroline BooraemDBDaniel BarnettTSTill S ZimmerAOAdam Orr
PMID: 39229090PMCID: PMC11370371DOI
With Caroline Booraem · Neuroscience (PhD)
Hippocampal astrocytes induce sex-dimorphic effects on memory.
Cell reports · 2024
AGAnna G OrrDBDaniel BarnettMWMinwoo Wendy JangTSTill S ZimmerCZConstance Zhou+2 more →
PMID: 38795347PMCID: PMC11234507DOI22 citations
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
AGAnna G OrrDBDaniel Barnett
PMID: 37940585PMCID: PMC10634555DOI25 citations
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
Science advances · 2023
AGAnna G OrrSJStephanie JackvonySMSamantha M MeadowsCZConstance ZhouRERobert E. Schwartz+1 more →
PMID: 37075107PMCID: PMC10115456DOI40 citations
With Stephanie Jackvony · Neuroscience (PhD) · Class of 2025
Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
Science advances · 2023
AGAnna G OrrSMSamantha M MeadowsSJStephanie JackvonyCZConstance ZhouRERobert E. Schwartz+1 more →
PMID: 37075107PMCID: PMC10115456DOI40 citations
With Samantha Meadows · Neuroscience (PhD) · Class of 2023
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Molecular neurodegeneration · 2022
DBDaniel BarnettTSTill S ZimmerAOAdam Orr
PMID: 35690868PMCID: PMC9188195DOI95 citations
With Daniel Barnett · Neuroscience (PhD) · Class of 2026
Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo.
Neuron · 2019
AGAnna G OrrSMSamantha MeadowsAAAmanda Acosta-RuizVAVanessa A Gutzeit+3 more →JLJoshua Levitz
PMID: 31784287PMCID: PMC7216301DOI63 citations
With Samantha Meadows · Neuroscience (PhD) · Class of 2023

Postdoc mentee

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Nature metabolism · 2025
AGAnna G OrrTSTill S ZimmerDBDaniel BarnettCBCaroline Booraem+3 more →AOAdam Orr
PMID: 41188644PMCID: PMC12616538DOI27 citations
With Till Zimmer · Postdoc mentee
Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease · 2025
AGAnna G OrrTSTill S ZimmerCZConstance ZhouEHEvelyn HardinSJStephanie Jackvony+2 more →
PMID: 40339618PMCID: PMC12240875DOI3 citations
With Till Zimmer · Postdoc mentee
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
bioRxiv : the preprint server for biology · 2024
AGAnna G OrrTSTill S ZimmerDBDaniel BarnettCBCaroline BooraemAOAdam Orr
PMID: 39229090PMCID: PMC11370371DOI
With Till Zimmer · Postdoc mentee
Hippocampal astrocytes induce sex-dimorphic effects on memory.
Cell reports · 2024
AGAnna G OrrTSTill S ZimmerMWMinwoo Wendy JangDBDaniel BarnettCZConstance Zhou+2 more →
PMID: 38795347PMCID: PMC11234507DOI22 citations
With Till Zimmer · Postdoc mentee
Hippocampal astrocytes induce sex-dimorphic effects on memory.
Cell reports · 2024
AGAnna G Orr MWMinwoo Wendy JangDBDaniel BarnettTSTill S ZimmerCZConstance Zhou+2 more →
PMID: 38795347PMCID: PMC11234507DOI22 citations
With Minwoo Wendy Jang · Postdoc mentee
Astrocytes in selective vulnerability to neurodegenerative disease.
Trends in neurosciences · 2024
AGAnna G OrrTSTill S ZimmerAOAdam Orr
PMID: 38521710PMCID: PMC11006581DOI43 citations
With Till Zimmer · Postdoc mentee
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Molecular neurodegeneration · 2022
TSTill S ZimmerDBDaniel BarnettAOAdam Orr
PMID: 35690868PMCID: PMC9188195DOI95 citations
With Till Zimmer · Postdoc mentee