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Anna G Orr, PhD
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Co-authored with Till Zimmer
Co-authored publications
Anna G Orr, PhD and Till Zimmer · 6 publications
CSV
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Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Nature metabolism
· 2025
AG
Anna G Orr
TS
Till S Zimmer
DB
Daniel Barnett
CB
Caroline Booraem
+3 more →
AO
Adam Orr
PMID:
41188644
·
PMCID:
PMC12616538
·
DOI
·
27 citations
·
Abstract
Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology.
Neurobiology of disease
· 2025
AG
Anna G Orr
TS
Till S Zimmer
CZ
Constance Zhou
EH
Evelyn Hardin
SJ
Stephanie Jackvony
+2 more →
PMID:
40339618
·
PMCID:
PMC12240875
·
DOI
·
3 citations
·
Abstract
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
bioRxiv : the preprint server for biology
· 2024
AG
Anna G Orr
TS
Till S Zimmer
DB
Daniel Barnett
CB
Caroline Booraem
AO
Adam Orr
PMID:
39229090
·
PMCID:
PMC11370371
·
DOI
·
Abstract
Hippocampal astrocytes induce sex-dimorphic effects on memory.
Cell reports
· 2024
AG
Anna G Orr
TS
Till S Zimmer
MW
Minwoo Wendy Jang
DB
Daniel Barnett
CZ
Constance Zhou
+2 more →
PMID:
38795347
·
PMCID:
PMC11234507
·
DOI
·
22 citations
·
Abstract
Astrocytes in selective vulnerability to neurodegenerative disease.
Trends in neurosciences
· 2024
AG
Anna G Orr
TS
Till S Zimmer
AO
Adam Orr
PMID:
38521710
·
PMCID:
PMC11006581
·
DOI
·
43 citations
·
Abstract
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Molecular neurodegeneration
· 2022
TS
Till S Zimmer
DB
Daniel Barnett
AO
Adam Orr
PMID:
35690868
·
PMCID:
PMC9188195
·
DOI
·
95 citations
·
Abstract