RecruitingObservationalNCT04613921 ↗Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure (ACLF): iNdications and outComEs
Active, not recruitingObservationalNCT05185232 ↗Utilizing PCORnet to Support Transition From Pediatric to Adult Centered Care and Reduce Gaps in Recommended Care in Patients With Congenital Heart DiseaseHarsimran SinghPIInterventionOther: Impact of gaps in care/loss to healthcare follow-upDatesApr 2022 – Oct 2023 (est.)SponsorPatient-Centered Outcomes Research InstituteCongenital Heart DiseaseComorbidities and Coexisting Conditions
Active, not recruitingObservationalNCT05465122 ↗Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical TrialDana LeiferPIInterventionProcedure: Carotid Endarterectomy · Procedure: FDA-approved carotid stents · Other: Intensive Medical ManagementDatesJul 2022 – Aug 2027 (est.)SponsorMayo ClinicStenoses, Carotid
Enrolling by invitationObservationalNCT05779475 ↗An Observational Study of Patients With Moderate Parkinson's DiseaseHarini SarvaPIInterventionOther: No treatment givenDatesApr 2023 – Mar 2030 (est.)SponsorNovo Nordisk Pharmaceuticals, Inc.Parkinson Disease
RecruitingObservationalNCT06170268 ↗Alzheimer's National Registry for Treatment and DiagnosticsMiran W SalgadoPISonja BlumPIInterventionOther: Routine Care DocumentationDatesOct 2022 – Dec 2032 (est.)SponsorAlzheimer's Association National OfficeAlzheimer Disease
RecruitingObservationalNCT06388421 ↗DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)Robert J. KanerPIInterventionOther: Prospective study assessmentsDatesJan 2025 – Sep 2030 (est.)SponsorUnited TherapeuticsPulmonary Hypertension Due to Lung Diseases and HypoxiaPulmonary HypertensionInterstitial Lung Disease
RecruitingObservationalNCT06424327 ↗Pulmonary Segmentectomy for Lung Cancer: A Real-World International Registry-TSOG 108Nasser K AltorkiPIInterventionOther: Patient-Reported Outcomes Measurement Information SystemDatesMay 2024 – May 2029 (est.)SponsorMemorial Sloan Kettering Cancer CenterLung CancerLung Cancer Stage I
CompletedObservationalNCT00898365 ↗Renal Tumors Classification, Biology, and Banking StudyAlexander Ja-Ho ChouPIInterventionOther: Cytology Specimen Collection Procedure · Other: Laboratory Biomarker AnalysisDatesFeb 2006 – Mar 2026SponsorChildren's Oncology GroupAdult Cystic NephromaAnaplastic Kidney Wilms TumorAngiolipoma+22 more
CompletedObservationalNCT03326076 ↗Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure RegistryDarshana M DadhaniaPIInterventionDiagnostic test: Donor-derived cell-free DNA (AlloSure®) · Other: Standard care · Diagnostic test: Peripheral blood gene expression profiling (AlloMap Kidney) · Diagnostic test: Analytic platform (IBox)DatesJan 2018 – Jun 2025 (est.)SponsorCareDx, Inc.Kidney Transplant Rejection
TerminatedObservationalNCT03692897 ↗An Observational Study of Patients With Chronic Hepatitis B (CHB) InfectionRobert S. BrownPIInterventionOther: All approved therapies for the treatment of Chronic Hepatitis B (CHB)DatesOct 2018 – Sep 2025SponsorTARGET PharmaSolutions, Inc.Hepatitis BHepatitisLiver Diseases
TerminatedObservationalNCT04293406 ↗WCM Catchment Prostate Cancer Health Impact Program (pCHIP)Joseph Reginald OsbornePIInterventionOther: Decision Navigation Intervention (DNI)DatesFeb 2021 – Apr 2024SponsorWeill Medical College of Cornell UniversityProstate Cancer
CompletedObservationalNCT04574596 ↗MDRO: Study of Highly Resistant Escherichia ColiMichael SatlinPIInterventionOther: no InterventionDatesNov 2020 – Jun 2021SponsorDuke UniversityE Coli Infection
CompletedObservationalNCT04588363 ↗An Observational Cohort Study to Determine Late Outcomes and Immunological Responses After Infection With SARS-CoV-2 in Children With and Without Multisystem Inflammatory Syndrome (MIS-C)Karen AckerPIInterventionOther: SARS-CoV-2 and/or MIS-C ExposureDatesNov 2020 – Mar 2023SponsorNational Institute of Allergy & Infectious DiseasesSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Multisystem Inflammatory Syndrome in Children (MIS-C)Coronavirus Disease 2019 (COVID-19)
CompletedObservationalNCT04710212 ↗Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies (SCENE)Michael SatlinPIInterventionOther: No intervention.DatesMar 2021 – Dec 2021SponsorDuke UniversityHematologic MalignancyLeukemia, AcuteNeutropenia+1 more
CompletedObservationalNCT04877652 ↗DR REGISTRY: Prospective Observational Study of Decongestion in Acute Heart Failure Patients With Insufficient Response to DiureticsDavid MajurePIInterventionOther: Standard of careDatesNov 2021 – May 2022SponsorRevamp Medical Ltd.Acute Decompensated Heart Failure
CompletedObservationalNCT04890314 ↗Prostate Cancer - Comparative Outcomes of New Conceptual Paradigms for TreatmentJim C. HuPIInterventionOther: Patient-reported questionnaireDatesMay 2021 – Apr 2024· Results postedSponsorWeill Medical College of Cornell UniversityProstate Cancer
TerminatedObservationalNCT04926857 ↗DEFINE AFib Atrial Fibrillation - Development of a Predictive Model for Future Health Care Utilization From Measurements Collected From an Implantable Cardiac Monitor.Gioia TurittoPIInterventionOther: Non-InterventionalDatesJun 2021 – Jan 2024· Results postedSponsorMedtronic, Inc.Atrial Fibrillation
CompletedObservationalNCT04930666 ↗The Development and Pilot Testing of a Brief Shared Decision-Making Intervention to Improve Palliative Care Outcomes for Adults With Advanced Lung DiseaseRobert J. KanerPIInterventionOther: BRief intervention to Enhance Adherence to Treatment and HEalth advice in Advanced Lung DiseaseDatesNov 2021 – Feb 2025SponsorColumbia University Medical CenterPulmonary Disease, Chronic ObstructiveLung Diseases, Interstitial
TerminatedObservationalNCT05008874 ↗Prospective, Retrospective, Multicenter, Observational Study of Disease Progression in Adults With Inherited Forms of Spastic ParaplegiaZuhal ErgonulPIInterventionOther: Natural History ObservationDatesJun 2021 – May 2025SponsorSwanBio Therapeutics LimitedAMNAMN Gene MutationX-ALD
CompletedObservationalNCT05074875 ↗Post COVID-19 Hypoxemic Respiratory Failure Residual Pathophysiologic OutcomesRobert J. KanerPIInterventionOther: Questionnaires and Patient Reported Outcomes (PROs) · Diagnostic test: Nasal Swab COVID-19 reverse transcription polymerase chain reaction test (RT-PCR) · Genetic: Blood Samples for Biomarkers · Diagnostic test: High Resolution Computed Tomography · Diagnostic test: Physical Exam and Vital Signs · Diagnostic test: Medical Research Council Sum Score · Diagnostic test: Hand Grip Strength · Diagnostic test: Spirometry · Diagnostic test: Diffusing Capacity of Carbon Monoxide · Diagnostic test: 6 Minute Walk Test · Diagnostic test: Sit to Stand (STS) MeasurementDatesJan 2021 – May 2023SponsorWeill Medical College of Cornell UniversityCovid19