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Scholars @ Weill Cornell Medicine

Help & supportPhase 1 prototype

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Scholars8,800 Publications201,348 Funding7,267 Clinical research190

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Browse

Scholars8,800 Publications201,348 Funding7,267 Clinical research190

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Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional166
Observational24

Phase

Not applicable138
Not reported24
Phase 311
Phase 28
Phase 46
Phase 2/33

Investigator

Jim W. Cheung10
Brian DeRubertis8
James E. Ip8
Geoffrey W Bergman6
Shmuel Chen6

Show all 50Show fewer

Department

Medicine83
Surgery31
Cardiothoracic Surgery11
Psychiatry11
Neurological Surgery10

Show all 17Show fewer

Condition

Atrial Fibrillation19
Heart Failure15
Stroke8
Cardiovascular Diseases7
Chronic Limb-Threatening Ischemia7

Intervention type

Device190
Drug807
Other202
Biological157
Procedure127
Behavioral83

Sponsor type

Industry139
WCM (investigator-initiated)31
Other academic18
Cooperative group1
NIH1

Start date

Has results posted41

Device×Clear all

Showing 141–160 of 190 studiesSort:

TerminatedInterventional · Not applicableNCT03820947 ↗
Global, Post-Market, Prospective, Multi-Center, Randomized Controlled Trial of the VenaSeal™ Closure System vs. Surgical Stripping or Endothermal Ablation (ETA) for the Treatment of Early & Advanced Stage Superficial Venous Disease
Neil M KhilnaniPI
Intervention
Device: VenaSeal™ System · Device: Endothermal Ablation (ETA) · Procedure: Surgical Stripping
Dates

FiltersClear all

Status

Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Completed52
Terminated11

Study type

Interventional166
Observational24

Phase

Not applicable138
Not reported24
Phase 311
Phase 28
Phase 46
Phase 2/33

Investigator

Jim W. Cheung10
Brian DeRubertis8
James E. Ip8
Geoffrey W Bergman6
Shmuel Chen6

Show all 50Show fewer

Department

Medicine83
Surgery31
Cardiothoracic Surgery11
Psychiatry11
Neurological Surgery10

Show all 17Show fewer

Condition

Atrial Fibrillation19
Heart Failure15
Stroke8
Cardiovascular Diseases7
Chronic Limb-Threatening Ischemia7

Intervention type

Device190
Drug807
Other202
Biological157
Procedure127
Behavioral83

Sponsor type

Industry139
WCM (investigator-initiated)31
Other academic18
Cooperative group1
NIH1

Start date

Has results posted41

Device×Clear all

Showing 141–160 of 190 studiesSort:

TerminatedInterventional · Not applicableNCT03820947 ↗
Global, Post-Market, Prospective, Multi-Center, Randomized Controlled Trial of the VenaSeal™ Closure System vs. Surgical Stripping or Endothermal Ablation (ETA) for the Treatment of Early & Advanced Stage Superficial Venous Disease
Neil M KhilnaniPI
Intervention
Device: VenaSeal™ System · Device: Endothermal Ablation (ETA) · Procedure: Surgical Stripping
Dates

Manish Ashwin Parikh4

Mehraneh Dorna Jafari2

David Leslie Carr-Locke1

Daniel Joseph Holzwanger1

Obstetrics and Gynecology6

Rehabilitation Medicine6

Otolaryngology Head and Neck Surgery1

Radiation Oncology1

Show all 50

Show fewer

Ischemic Stroke7
Coronary Artery Disease6
Aortic Valve Stenosis4
Arrhythmias, Cardiac4
Bradycardia4
Chronic Pain4
Depression4
Heart Diseases4
Liver Diseases4
Mitral Valve Insufficiency4
Atrioventricular Block3
Carcinoma, Hepatocellular3
Depressive Disorder, Major3
Depressive Disorder, Treatment-Resistant3
Heart Valve Diseases3
Neoplasms3
Prostatic Neoplasms3
Pulmonary Arterial Hypertension3
Tricuspid Valve Insufficiency3
Alzheimer Disease2
Angina Pectoris2
Anxiety Disorders2
Aortic Aneurysm, Thoracoabdominal2
Blood Loss, Surgical2
Cognitive Dysfunction2
Colonic Neoplasms2
Death, Sudden, Cardiac2
Dissection, Thoracic Aorta2
Fatigue2
Gastric Outlet Obstruction2
Heart Failure, Diastolic2
Hypertension2
Liver Neoplasms2
Lung Diseases, Interstitial2
Nail Diseases2
Obesity2
Parkinson Disease2
Peripheral Arterial Disease2
Recurrence2
Tachycardia, Ventricular2
Varicose Ulcer2
Vascular Diseases2
Venous Thrombosis2
Acute Coronary Syndrome1
Acute Kidney Injury1

Radiation

Diagnostic test31

Dietary supplement14

Combination product11

Genetic7

Feb 2020 – Jun 2024· Results posted

Sponsor

Medtronic Vascular, Inc.

Venous Reflux

CompletedInterventional · Not applicableNCT03973281 ↗

A Randomized, Controlled Study to Evaluate the Safety and Effectiveness of the Materna Prep Device to Pre-stretch the Vaginal Canal and Pelvic Floor Tissues in Preparation for Vaginal Delivery

Daniel W SkupskiPI

Intervention: Device: Materna Prep Device · Other: Standard of Care (SOC)
Dates: Dec 2019 – Jul 2026
Sponsor: Materna Medical

Vaginal DeliveryPelvic Organ Prolapse

CompletedInterventional · Not applicableNCT04060680 ↗

Extravascular ICD Pivotal Study (EV ICD)

Jim W. CheungPI

Intervention: Device: Defibrillation using the Extravascular ICD
Dates: Sep 2019 – Apr 2022· Results posted
Sponsor: Medtronic, Inc.

TachycardiaVentricular Arrythmia

CompletedInterventional · Not applicableNCT04103749 ↗

Global Prospective Case Series Using a Single-Use Duodenoscope

David Leslie Carr-LockePI

Intervention: Device: Exalt Model D Single-Use Duodenoscope
Dates: Mar 2021 – Nov 2022· Results posted
Sponsor: Boston Scientific Corporation

Endoscopic Retrograde Cholangiopancreatography

TerminatedInterventional · Phase 3NCT04142658 ↗

A Prospective, Randomized, Active (Warfarin) Controlled, Parallel-arm Clinical Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely and Effectively on Apixaban

Christopher LauPI

Intervention: Drug: Apixaban 5 MG · Drug: Apixaban 2.5 MG · Drug: Warfarin · Device: On-X Aortic Mechanical Valve
Dates: May 2020 – Dec 2022· Results posted
Sponsor: CryoLife, Inc.

Aortic Valve DiseaseAortic Valve StenosisAortic Valve Failure

CompletedObservationalNCT04175626 ↗

BIOTRONIK - A Prospective Multicenter Study to Confirm the SaFety and Effectiveness of the Orsiro SiroLimus Eluting Coronary Stent System in the Treatment Of Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions - VII

Geoffrey W BergmanPI

Intervention: Device: Orsiro DES
Dates: Jan 2020 – Jan 2022· Results posted
Sponsor: BIOTRONIK GmbH & Co.

Coronary Artery DiseaseAtherosclerosis, CoronaryMyocardial Ischemia+3 more

CompletedObservationalNCT04281160 ↗

Patient Centered Outcomes Analysis for MS Using a Mobile Application

Jai S. PerumalPI

Intervention: Device: BeCare Mobile App
Dates: Feb 2020 – Sep 2023 (est.)
Sponsor: Weill Medical College of Cornell University

Multiple Sclerosis

CompletedInterventional · Not applicableNCT04291014 ↗

A Dose Selection Trial of Light Therapy for Impaired Sleep in Parkinson's Disease

Harini SarvaPI

Intervention: Device: SunRay Light Boxes
Dates: Sep 2020 – Nov 2022· Results posted
Sponsor: The General Hospital Corporation (dba Massachusetts General Hospital)

Parkinson DiseaseSleep DisorderFatigue

CompletedObservationalNCT04370691 ↗

JET Enhanced Thrombectomy Intervention Registry - JETi Registry

Brian DeRubertisPI

Intervention: Device: JETi lower extremity arterial thrombosis
Dates: Mar 2020 – Jan 2024· Results posted
Sponsor: Abbott Cardiovascular Systems, Inc.

Arterial Thrombosis

CompletedInterventional · Phase 2/3NCT04396860 ↗

A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab Versus Temozolomide in Patients With Newly Diagnosed MGMT (Tumor O-6-Methylguanine DNA Methyltransferase) Unmethylated Glioblastoma

Rajiv S. MaggePI

Intervention: Procedure: Contrast-enhanced Magnetic Resonance Imaging · Biological: Ipilimumab · Biological: Nivolumab · Device: NovoTTF-100A Device · Other: Quality-of-Life Assessment · Other: Questionnaire Administration · Radiation: Radiation Therapy · Drug: Temozolomide
Dates: Sep 2020 – Jan 2023· Results posted
Sponsor: NRG Oncology

GliosarcomaMGMT-Unmethylated Glioblastoma

CompletedInterventional · Not applicableNCT04402632 ↗

A Study of the Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System In the Treatment of Subacute and Chronic Subdural HEmatoma (EMBOLISE)

Jared KnopmanPI

Intervention: Procedure: Surgical Management · Device: Onyx™ Liquid Embolic System (LES) Embolization · Other: Observation Only
Dates: Oct 2020 – Dec 2024
Sponsor: Medtronic, Inc.

Subdural Hematoma

CompletedInterventional · Phase 4NCT04422795 ↗

The Evaluation of External Thermomechanical Stimulation for Pain Reduction in Patients Undergoing Nail Injection

Shari LipnerPI

Intervention: Device: External thermomechanical device delivering cold and vibration stimuli · Device: External thermomechanical device without delivering cold and vibration stimuli · Drug: Ethyl chloride skin refrigerant spray
Dates: Feb 2024 – Feb 2025 (est.)
Sponsor: Weill Medical College of Cornell University

Nail Diseases

TerminatedObservationalNCT04431544 ↗

AcQMap® US Registry of Procedural and Long-term Clinical Outcomes (Discover-US)

Steven M MarkowitzPI

Intervention: Device: AcQMap System
Dates: Sep 2020 – Nov 2023
Sponsor: Acutus Medical Inc.

Ablation of Arrhythmia's

CompletedInterventional · Phase 2NCT04456998 ↗

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Clinical Study to Evaluate the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

Irina SobolPI

Intervention: Drug: GB002 (seralutinib) · Drug: Placebo · Device: Generic Dry Powder Inhaler
Dates: Nov 2020 – Oct 2022· Results posted
Sponsor: Gossamer Bio

Pulmonary Artery Hypertension

CompletedInterventional · Not applicableNCT04559945 ↗

The LEADLESS II IDE Study (Phase II): A Safety and Effectiveness Trial for a Leadless Pacemaker System

James E. IpPI

Intervention: Device: Aveir VR Leadless Pacemaker System
Dates: Nov 2020 – Jul 2022· Results posted
Sponsor: Abbott Cardiovascular Systems, Inc.

Cardiac Rhythm DisorderBradycardia

CompletedInterventional · Not applicableNCT04580914 ↗

Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation

Jim W. CheungPI

Intervention: Device: Treatment with IntellaNav StablePoint Ablation Catheter
Dates: Apr 2021 – Jun 2023· Results posted
Sponsor: Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

CompletedInterventional · Not applicableNCT04618718 ↗

Cerebral Protection in Transcatheter Aortic Valve Replacement - The PROTEMBO C Trial

Shmuel ChenPI

Intervention: Device: cerebral embolic protection during TAVR
Dates: Jul 2020 – Nov 2022· Results posted
Sponsor: Protembis GmbH

Valvular Heart Disease

CompletedObservationalNCT04628650 ↗

Self-Management of Chronic Pain Using a Digital Pain-Management Tool.

Neel MehtaPI

Intervention: Device: Digital Pain-Management Tool
Dates: May 2021 – May 2022
Sponsor: Weill Medical College of Cornell University

Chronic Pain

CompletedInterventional · Not applicableNCT04658940 ↗

AcQBlate Force Sensing Ablation System US IDE for Atrial Flutter (AcQForce Flutter)

Steven M MarkowitzPI

Intervention: Device: AcQBlate® Force Sensing Ablation System
Dates: Mar 2021 – May 2022· Results posted
Sponsor: Acutus Medical Inc.

Typical Atrial Flutter

CompletedObservationalNCT04668664 ↗

PORTAL: Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements

Reem Z. SharaihaPI

Intervention: Device: EchoTip® Insight™ Portosystemic Pressure Gradient Measurement System (EchoTip® Insight™)
Dates: Apr 2021 – Jun 2022
Sponsor: Cook Research, Inc.

Liver CirrhosisLiver DiseasesHypertension, Portal

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