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ScholarsBetaWeill Cornell Medicine

Overview

Jim Cheung, MD, FACC, FHRS is Professor of Medicine, Director of the Cornell Cardiac Electrophysiology Fellowship Program, and Director of Clinical Electrophysiology Research at Weill Cornell Medicine. A native New Yorker and valedictorian from the Bronx High School of Science, he graduated summa cum laude in Biochemical Sciences from Harvard University in 1995 and received his medical degree at Harvard Medical School in 1999. He completed his internship and residency training at the Massachusetts General Hospital. Dr. Cheung performed his fellowship training in cardiology and cardiac electrophysiology at New York Presbyterian Hospital - Cornell University Medical Center.

Dr. Cheung specializes in the treatment of all heart rhythm disorders. His areas of expertise include catheter ablation treatment of atrial fibrillation (AF) and complex atrial tachycardia (with specialization on the use of zero and near-zero X-ray exposure techniques), treatment of ventricular arrhythmias (with extensive experience in robotic magnetic navigation-guided ablation), and cardiac device implantation (with emphasis on His/left bundle region pacing, cardiac resynchronization therapy devices and subcutaneous implantable cardioverter-defibrillators [ICDs]).

He is co-founder of the Weill Cornell Cardiovascular Outcomes Research Group (CORG) whose mission is to assess the effectiveness and outcomes of cardiovascular interventions with a focus on the treatment of heart rhythm disorders and structural heart disease and the improvement of healthcare delivery. He has published original studies, review articles and editorials on outcomes of catheter ablation treatment of AF and ventricular arrhythmias, mechanisms behind arrhythmia disorders, genetics of inherited ventricular arrhythmia syndromes, syncope and other aspects of heart rhythm disorders. Dr. Cheung is currently conducting research on areas including: 1) real-world outcomes of catheter ablation therapies, 2) genetic factors on the development of arrhythmias in young patients, 3) innovative arrhythmia devices (e.g. ICDs) and treatments for AF and 4) robotic magnetic navigation-guided ablation of complex arrhythmias. 

Highlights

  1. 1
    Journal of the American College of Cardiology · 2023
    MSMatthew S. SimonLKLuke KimJEJames E. IpCFChristopher F Liu+3 more →JWJim W. Cheung
    PMID: 37100488DOISenior author58 citations
  2. 2
    Journal of cardiovascular electrophysiology · 2020
    JWJim W. CheungJEJames E. IpGTGeorge ThomasCFChristopher F Liu+2 more →BBBruce B Lerman
    PMID: 32449825DOIFirst author31 citations
  3. 3
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    MSMatthew S. SimonLKLuke KimJEJames E. IpCFChristopher F Liu+3 more →JWJim W. Cheung
    PMID: 39727102PMCID: PMC11707385DOISenior author4 citations

Publications

200 publications

Funding

4 grants

Active

3 grants
  • Sub-PI
    The Rhythm Evaluation for Anticoagulation with Continuous Monitoring for Atrial Fibrillation (REACT-AF) trial
    National Heart, Lung, and Blood Institute · 2023–2029 · via Northwestern University_
    UH3HL165065-05
  • Sub-PI
    HIS-BUNDLE Corrective Pacing In Heart Failure (HIS-CRT)
    National Heart, Lung, and Blood Institute · 2023–2027 · via University of Rochester
    R01HL160795-05
  • Sub-PI
    Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing with a Left Ventricular Epicardial Lead in Patients with Heart Failure (HF) with Left Ventricular Ejection Fraction (LVEF)≤50% and with either a Wide QRS Complex (>130 ms) or with/anticipated >40% Pacing Randomized Clinical Trial (RCT)
    Patient-Centered Outcomes Research Institute · 2023–2026 · via Baylor College of Medicine
    PLACER-2021C3-24160
Completed grants (1)
  • Co-I
    MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER)
    National Heart, Lung, and Blood Institute · 2019–2025
    R01HL144541-05

Clinical research

21 studies

Active

13 studies
  • PI
    The ReMATCH Study is a Prospective, Single Arm, Open Label, Multi-center, Study Utilizing the FARAPULSE PFA System, Including the FARAWAVE and FARAPOINT PFA Catheters
    NA · Boston Scientific Corporation · OPEN TO ACCRUAL (as of 2026)
    Persistent Atrial Fibrillation
    NCT06735534
  • PI
    Comparison of Extravascular ICD to Transvenous and Subcutaneous ICD in Specialized Populations
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
  • PI
    Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
    NA · Boston Scientific Corporation · OPEN TO ACCRUAL (as of 2026)
    Heart Failure - NYHA II - IV
    NCT07069738
  • PI
    Barriers to Extraction of Cardiac Implantable Electronic Devices Associated with Device and Systemic Infections
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
  • PI
    Comprehensive Cardiac Electrophysiology Clinical Database Project for the Study of Heart Rhythm Disorders
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
  • PI
    Efficacy and Safety of Pulsed Field Ablation for Atrial Fibrillation
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
  • PI
    Modeling Cardiac Ryanodine Receptor (RyR2) Mutations Causing Polymorphic Ventricular Tachycardia at Rest with Patient-Specific Induced Pluripotent Stem Cells
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)
  • PI
    Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing With a Left Ventricular Epicardial Lead in Patients With Heart Failure (HF) With Left Ventricular Ejection Fraction (LVEF)≤50% and With Either a Wide QRS Complex (>130 ms) or With/Anticipated >40% Pacing Randomized Clinical Trial
    NA · Baylor College of Medicine · OPEN TO ACCRUAL (as of 2024)
    Heart Failure; Heart Failure With Reduced Ejection Fraction; AV Block; LBBB; RBBB; Intraventricular Conduction Delay; Pacing-Induced Cardiomyopathy
    NCT05650658
  • PI
    REACT-AF: Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
    PHASE3 · Northwestern University Feinberg School of Medicine · OPEN TO ACCRUAL (as of 2023)
    Atrial Fibrillation
    NCT05836987
  • PI
    His-Bundle Corrective Pacing in Heart Failure
    NA · University of Rochester · OPEN TO ACCRUAL (as of 2023)
    Right Bundle-Branch Block; Heart Failure; His-bundle Pacing; Cardiac Resynchronization Therapy
    NCT05265520
  • PI
    Psychosocial Support for Patients with Takotsubo Syndrome
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2023)
  • PI
    Mobile Telemetry Monitoring for the Initiation of Sotalol and Dofetilide
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2022)
  • PI
    Next Generation Sequencing and Molecular Characterization of Cardiovascular Diseases
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2020)
Completed & closed trials (8)
  • PI
    A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation
    NA · Boston Scientific Corporation · IRB STUDY CLOSURE (as of 2026)
    Persistent Atrial Fibrillation
    NCT05443594
  • PI
    A Stylet-Driven ICD Lead Intended for Conduction System Pacing IDE Study
    NA · Abbott Cardiovascular Systems, Inc. · CLOSED TO ACCRUAL (as of 2026)
    Heart Failure; Ventricular Arrythmia
    NCT06830746
  • PI
    Cryoablation for Monomorphic Ventricular Tachycardia IDE Study: EFS and Pivotal
    NA · Adagio Medical · CLOSED TO ACCRUAL (as of 2025)
    Sustained VT
    NCT05675865
  • PI
    A Prospective Randomized Multicenter Global Study Comparing Pulsed Field Ablation (PFA) Versus Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
    NA · Boston Scientific Corporation · CLOSED TO ACCRUAL (as of 2025)
    Persistent Atrial Fibrillation
    NCT06096337
  • PI
    Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation
    NA · Boston Scientific Corporation · IRB STUDY CLOSURE (as of 2024)
    Paroxysmal Atrial Fibrillation
    NCT04580914
  • PI
    Extravascular ICD Pivotal Study (EV ICD)
    NA · Medtronic, Inc. · IRB STUDY CLOSURE (as of 2024)
    Tachycardia; Ventricular Arrythmia
    NCT04060680
  • PI
    Extravascular ICD Pivotal Study (EV ICD)
    NA · Medtronic, Inc. · IRB STUDY CLOSURE (as of 2024)
    Tachycardia; Ventricular Arrythmia
    NCT04060680
  • PI
    Radiofrequency Ablation of Atrial Fibrillation Under Apnea
    NA · Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2022)
    Atrial Fibrillation
    NCT04170894

Mentoring

1 menteeAll publications with mentees →