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Scholars/Li Gan, PhD/Co-authored with mentees

Co-authored publications with mentees

Li Gan, PhD · 41 publications across 18 mentees

PhD mentee

Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.
Neuron · 2026
LGLi GanNFNessa FoxeBLBangyan LiuMMMatthew MahoneyYFYilin Feng+8 more →
PMID: 42580340DOI
With Nessa Foxe · Neuroscience (PhD)
Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.
Neuron · 2026
LGLi GanBLBangyan LiuMMMatthew MahoneyYFYilin FengAMAlice Maria Giani+8 more →
PMID: 42580340DOI
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.
Neuron · 2026
LGLi GanMMMatthew MahoneyBLBangyan LiuYFYilin FengAMAlice Maria Giani+8 more →
PMID: 42580340DOI
With Matthew Mahoney · Neuroscience (PhD)
Humanized tauopathy chimeras uncover microglial and lncRNA strategies for neuroprotection.
bioRxiv : the preprint server for biology · 2026
LGLi GanAAAbulimiti AikedanRKRavi Kumar Nagiri WLWenjie Luo HTHagen Tilgner+1 more →
PMID: 42427519PMCID: PMC13345064DOI
With Abulimiti Aikedan · Physiology, Biophysics & Systems Biology (PhD)
Expanding roles of cGAS-STING signaling in neuroinflammation.
The Journal of clinical investigation · 2026
LGLi GanAAAbulimiti AikedanWFWeixi Feng SSSubhash Sinha
PMID: 42222892PMCID: PMC13221232DOI3 citations
With Abulimiti Aikedan · Physiology, Biophysics & Systems Biology (PhD)
Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.
bioRxiv : the preprint server for biology · 2026
LGLi GanNFNessa FoxeRMRoberta Marongiu YWYuansong WanEREileen Ruth S Torres+8 more →
PMID: 42146496PMCID: PMC13174672DOI
With Nessa Foxe · Neuroscience (PhD)
cGAS inhibition delays TDP-43-driven ALS Pathogenesis.
bioRxiv : the preprint server for biology · 2026
LGLi GanAAAbulimiti AikedanYLYajing Liu WFWeixi Feng SLSe-In Lee+5 more →
PMID: 41809005PMCID: PMC12970331DOI
With Abulimiti Aikedan · Physiology, Biophysics & Systems Biology (PhD)
STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.
bioRxiv : the preprint server for biology · 2025
LGLi GanNFNessa FoxeHCHao Chen LFLi Fan+4 more →WLWenjie Luo
PMID: 41446190PMCID: PMC12724505DOI
With Nessa Foxe · Neuroscience (PhD)
DAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.
Molecular neurodegeneration · 2025
LGLi GanNFNessa FoxeHCHao Chen LFLi Fan+4 more →WLWenjie Luo
PMID: 41331787PMCID: PMC12673724DOI3 citations
With Nessa Foxe · Neuroscience (PhD)
Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.
Communications biology · 2025
LGLi GanGCGillian CarlingCDClaire Dudley ClellandLFLi FanJZJingjie Zhu+1 more →
PMID: 40596721PMCID: PMC12218935DOI2 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.
Science (New York, N.Y.) · 2024
LGLi GanNFNessa FoxeLKLay KodamaLFLi FanDZDaphne Zhu+7 more →
PMID: 39607927PMCID: PMC12396121DOI39 citations
With Nessa Foxe · Neuroscience (PhD)
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Neuron · 2024
LGLi GanGKGillian K CarlingLFLi FanNFNessa FoxeDZDaphne Zhu+9 more →
PMID: 39353433PMCID: PMC11624100DOI68 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Neuron · 2024
LGLi GanNFNessa FoxeGKGillian K CarlingLFLi FanDZDaphne Zhu+9 more →
PMID: 39353433PMCID: PMC11624100DOI68 citations
With Nessa Foxe · Neuroscience (PhD)
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Neuron · 2024
LGLi GanYHYige HuangGKGillian K CarlingLFLi FanNFNessa Foxe+9 more →
PMID: 39353433PMCID: PMC11624100DOI68 citations
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
Cellular and pathological functions of tau.
Nature reviews. Molecular cell biology · 2024
LGLi GanCPCeleste Parra BravoSNSarah Naguib
PMID: 39014245DOI205 citations
With Celeste Parra Bravo · Neuroscience (PhD) · Class of 2025
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Molecular neurodegeneration · 2024
LGLi GanCPCeleste Parra BravoLFLi Fan SSSubhash Sinha
PMID: 38915105PMCID: PMC11197196DOI20 citations
With Celeste Parra Bravo · Neuroscience (PhD) · Class of 2025
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Cell · 2024
LGLi GanGKGillian K CarlingCPCeleste Parra BravoAMAlice Maria GianiYWYuansong Wan+7 more →
PMID: 38582079PMCID: PMC11365117DOI60 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Cell · 2024
LGLi GanCPCeleste Parra BravoAMAlice Maria GianiYWYuansong WanAJAvi J Samelson+7 more →
PMID: 38582079PMCID: PMC11365117DOI60 citations
With Celeste Parra Bravo · Neuroscience (PhD) · Class of 2025
Mechanisms of sex differences in Alzheimer's disease.
Neuron · 2024
LGLi GanGCGillian CarlingCLChloe Lopez-LeeEREileen Ruth S Torres
PMID: 38402606PMCID: PMC11076015DOI332 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
bioRxiv : the preprint server for biology · 2024
LGLi GanGKGillian K CarlingLFLi FanNFNessa FoxeHCHao Chen+5 more →
PMID: 38328219PMCID: PMC10849737DOI
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
bioRxiv : the preprint server for biology · 2024
LGLi GanNFNessa FoxeGKGillian K CarlingLFLi Fan HCHao Chen+5 more →
PMID: 38328219PMCID: PMC10849737DOI
With Nessa Foxe · Neuroscience (PhD)
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
bioRxiv : the preprint server for biology · 2024
LGLi GanYHYige HuangGKGillian K CarlingLFLi FanNFNessa Foxe+5 more →
PMID: 38328219PMCID: PMC10849737DOI
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
bioRxiv : the preprint server for biology · 2024
LGLi GanCPCeleste Parra BravoAJAvi J Samelson
PMID: 37398204PMCID: PMC10312804DOI644 citations
With Celeste Parra Bravo · Neuroscience (PhD) · Class of 2025
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Research square · 2023
LGLi GanGCGillian CarlingHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961627PMCID: PMC10635319DOI
With Gillian Carling · Neuroscience (PhD) · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Research square · 2023
LGLi GanNFNessa FoxeHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961627PMCID: PMC10635319DOI
With Nessa Foxe · Neuroscience (PhD)
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Research square · 2023
LGLi GanBLBangyan LiuHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961627PMCID: PMC10635319DOI
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Research square · 2023
LGLi GanYHYige HuangHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961627PMCID: PMC10635319DOI
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
bioRxiv : the preprint server for biology · 2023
LGLi GanGCGillian CarlingHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961594PMCID: PMC10634844DOI
With Gillian Carling · Neuroscience (PhD) · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
bioRxiv : the preprint server for biology · 2023
LGLi GanNFNessa FoxeHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961594PMCID: PMC10634844DOI
With Nessa Foxe · Neuroscience (PhD)
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
bioRxiv : the preprint server for biology · 2023
LGLi GanBLBangyan LiuHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961594PMCID: PMC10634844DOI
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
bioRxiv : the preprint server for biology · 2023
LGLi GanYHYige HuangHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961594PMCID: PMC10634844DOI
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.
Molecular neurodegeneration · 2023
LGLi GanBLBangyan LiuYHYige HuangSSSubhash SinhaSASadaf Amin
PMID: 37941028PMCID: PMC10634099DOI148 citations
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.
Molecular neurodegeneration · 2023
LGLi GanYHYige HuangBLBangyan LiuSSSubhash SinhaSASadaf Amin
PMID: 37941028PMCID: PMC10634099DOI148 citations
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging.
bioRxiv : the preprint server for biology · 2023
LGLi GanNFNessa FoxeCLChloe Lopez-LeeLFLi FanEREileen Ruth Torres+1 more →
PMID: 37781600PMCID: PMC10541118DOI
With Nessa Foxe · Neuroscience (PhD)
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
bioRxiv : the preprint server for biology · 2023
LGLi GanGCGillian CarlingCPCeleste Parra BravoAMAlice Maria GianiZZZeping Zhao+6 more →
PMID: 37745431PMCID: PMC10516028DOI
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
bioRxiv : the preprint server for biology · 2023
LGLi GanCPCeleste Parra BravoAMAlice Maria GianiZZZeping ZhaoAEAlessandro Evangelisti+6 more →
PMID: 37745431PMCID: PMC10516028DOI
With Celeste Parra Bravo · Neuroscience (PhD) · Class of 2025
Autophagy prevents microglial senescence.
Nature cell biology · 2023
LGLi GanBLBangyan LiuSASadaf Amin
PMID: 37308635DOI25 citations
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience · 2023
LGLi GanGKGillian K CarlingSASadaf AminYHYige HuangLFLi Fan+8 more →
PMID: 37095396PMCID: PMC10166855DOI237 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience · 2023
LGLi GanBLBangyan LiuSASadaf AminYHYige HuangLFLi Fan+8 more →
PMID: 37095396PMCID: PMC10166855DOI237 citations
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience · 2023
LGLi GanYHYige HuangSASadaf AminLFLi FanEREileen Ruth S Torres+8 more →
PMID: 37095396PMCID: PMC10166855DOI237 citations
With Yige Huang · Cell & Developmental Biology (PhD) · Class of 2025
Friend turned foe: TREM2 agonist in battles against tau.
The Journal of experimental medicine · 2022
LGLi GanGCGillian CarlingWLWenjie Luo
PMID: 36399126PMCID: PMC9680035DOI9 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Nature communications · 2022
LGLi GanBLBangyan LiuLFLi FanCCCarlo CondelloWLWenjie Luo
PMID: 35413950PMCID: PMC9005658DOI296 citations
With Bangyan Liu · Neuroscience (PhD) · Class of 2024
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
Science translational medicine · 2021
LGLi GanGKGillian K CarlingLFLi FanXNXiang NiuMBMatthew Brendel+4 more →
PMID: 34851693PMCID: PMC9345574DOI110 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia.
Current opinion in neurobiology · 2021
LGLi GanGCGillian CarlingSASadaf Amin
PMID: 34826653DOI25 citations
With Gillian Carling · Neuroscience (PhD) · Class of 2024

Postdoc mentee

Spatial isoform sequencing at single-cell resolution reveals cell-type-specific spatial isoform variability in multiple brain cell types.
Nature methods · 2026
LGLi Gan TKTaewoo Kim LMLieke MichielsenCFCareen Foord+5 more →HTHagen Tilgner
PMID: 42697995PMCID: PMC13545012DOI
With Taewoo Kim · Postdoc mentee
Discovery and Characterization of Inhibitors of Ubiquitin-Like Modifier Activating Enzyme 5 (UBA5): Targeting the UFMylation Pathway in Cancer and Neurodegenerative Diseases.
ACS chemical biology · 2026
LGLi Gan YWYuansong Wan SSSubhash Sinha
PMID: 42607158DOI
With Yuansong Wan · Postdoc mentee
Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.
Neuron · 2026
LGLi GanAMAlice Maria GianiBLBangyan LiuMMMatthew MahoneyYFYilin Feng+8 more →
PMID: 42580340DOI
With Alice Giani · Postdoc mentee
Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.
Neuron · 2026
LGLi Gan YFYilin FengBLBangyan LiuMMMatthew MahoneyAMAlice Maria Giani+8 more →
PMID: 42580340DOI
With Yilin Feng · Postdoc mentee
cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy.
Nature neuroscience · 2026
LGLi GanMPMika P CadizLFLi FanDZDaphne ZhuRKRavi Kumar Nagiri+8 more →
PMID: 42527551PMCID: PMC13533845DOI
With Mika Cadiz · Postdoc mentee
Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice.
Molecular neurodegeneration · 2026
LGLi Gan SNSarah Naguib SGShiaoching Gong LFLi Fan
PMID: 42464356DOI
With Sarah Naguib · Postdoc mentee
Expanding roles of cGAS-STING signaling in neuroinflammation.
The Journal of clinical investigation · 2026
LGLi Gan WFWeixi FengAAAbulimiti AikedanSSSubhash Sinha
PMID: 42222892PMCID: PMC13221232DOI3 citations
With Weixi Feng · Postdoc mentee
Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity.
bioRxiv : the preprint server for biology · 2026
LGLi Gan YWYuansong Wan RMRoberta MarongiuEREileen Ruth S TorresLFLi Fan+8 more →
PMID: 42146496PMCID: PMC13174672DOI
With Yuansong Wan · Postdoc mentee
CAR-A astrocytes for Alzheimer's: Promise and challenge.
Cell stem cell · 2026
LGLi Gan SLSe-In Lee WLWenjie Luo
PMID: 42102723DOI
With Se-In Lee · Postdoc mentee
Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer's disease.
bioRxiv : the preprint server for biology · 2026
LGLi Gan SLSe-In Lee YWYuansong Wan WFWeixi FengJZJingjie Zhu+1 more →
PMID: 41890040PMCID: PMC13015489DOI
With Se-In Lee · Postdoc mentee
Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer's disease.
bioRxiv : the preprint server for biology · 2026
LGLi Gan YWYuansong Wan SLSe-In Lee WFWeixi FengJZJingjie Zhu+1 more →
PMID: 41890040PMCID: PMC13015489DOI
With Yuansong Wan · Postdoc mentee
Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer's disease.
bioRxiv : the preprint server for biology · 2026
LGLi Gan WFWeixi Feng YWYuansong Wan SLSe-In LeeJZJingjie Zhu+1 more →
PMID: 41890040PMCID: PMC13015489DOI
With Weixi Feng · Postdoc mentee
cGAS inhibition delays TDP-43-driven ALS Pathogenesis.
bioRxiv : the preprint server for biology · 2026
LGLi Gan SLSe-In Lee YLYajing Liu WFWeixi FengAAAbulimiti Aikedan+5 more →
PMID: 41809005PMCID: PMC12970331DOI
With Se-In Lee · Postdoc mentee
cGAS inhibition delays TDP-43-driven ALS Pathogenesis.
bioRxiv : the preprint server for biology · 2026
LGLi Gan WFWeixi Feng YLYajing LiuAAAbulimiti AikedanSLSe-In Lee+5 more →
PMID: 41809005PMCID: PMC12970331DOI
With Weixi Feng · Postdoc mentee
cGAS inhibition delays TDP-43-driven ALS Pathogenesis.
bioRxiv : the preprint server for biology · 2026
LGLi Gan WQWenhui Qu YLYajing Liu WFWeixi FengAAAbulimiti Aikedan+5 more →
PMID: 41809005PMCID: PMC12970331DOI
With Wenhui Qu · Postdoc mentee
cGAS inhibition delays TDP-43-driven ALS Pathogenesis.
bioRxiv : the preprint server for biology · 2026
LGLi Gan YLYajing Liu WFWeixi FengAAAbulimiti AikedanSLSe-In Lee+5 more →
PMID: 41809005PMCID: PMC12970331DOI
With Yajing Liu · Postdoc mentee
Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.
Research square · 2026
LGLi Gan SNSarah Naguib SGShiaoching Gong LFLi Fan
PMID: 41684752PMCID: PMC12893066DOI
With Sarah Naguib · Postdoc mentee
cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy.
bioRxiv : the preprint server for biology · 2026
LGLi GanMCMika CadizLFLi FanDZDaphne ZhuRKRavi Kumar Nagiri+9 more →
PMID: 41676493PMCID: PMC12889442DOI
With Mika Cadiz · Postdoc mentee
Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice.
bioRxiv : the preprint server for biology · 2026
LGLi Gan SNSarah Naguib SGShiaoching Gong LFLi Fan
PMID: 41648346PMCID: PMC12871286DOI
With Sarah Naguib · Postdoc mentee
STING-IFN-CH25H lipid axis links innate immune activation to tau pathology.
bioRxiv : the preprint server for biology · 2025
LGLi Gan YWYuansong Wan HCHao Chen LFLi Fan+4 more →WLWenjie Luo
PMID: 41446190PMCID: PMC12724505DOI
With Yuansong Wan · Postdoc mentee
Dopamine receptor 1-expressing cells in the ventral hippocampus encode cocaine-context associations.
Research square · 2025
LGLi Gan SNSarah Naguib
PMID: 41356351PMCID: PMC12676452DOI
With Sarah Naguib · Postdoc mentee
Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.
Communications biology · 2025
LGLi Gan SLSe-In LeeCDClaire Dudley ClellandLFLi FanJZJingjie Zhu+1 more →
PMID: 40596721PMCID: PMC12218935DOI2 citations
With Se-In Lee · Postdoc mentee
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.
Immunity · 2025
LGLi Gan SNSarah NaguibEREileen Ruth TorresSLSe-In LeeJZJingjie Zhu+10 more →
PMID: 40555238PMCID: PMC12406129DOI25 citations
With Sarah Naguib · Postdoc mentee
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway.
Immunity · 2025
LGLi Gan SLSe-In Lee SNSarah NaguibEREileen Ruth TorresJZJingjie Zhu+10 more →
PMID: 40555238PMCID: PMC12406129DOI25 citations
With Se-In Lee · Postdoc mentee
APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.
bioRxiv : the preprint server for biology · 2025
LGLi Gan SNSarah NaguibCLChloe Lopez-LeeEREileen Ruth TorresSLSe-In Lee+8 more →
PMID: 38712164PMCID: PMC11071490DOI
With Sarah Naguib · Postdoc mentee
APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.
bioRxiv : the preprint server for biology · 2025
LGLi GanCLChloe Lopez-LeeSNSarah NaguibEREileen Ruth TorresSLSe-In Lee+8 more →
PMID: 38712164PMCID: PMC11071490DOI
With Chloe Lopez-Lee · Neuroscience · Class of 2024
APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.
bioRxiv : the preprint server for biology · 2025
LGLi Gan SLSe-In Lee SNSarah NaguibCLChloe Lopez-LeeEREileen Ruth Torres+8 more →
PMID: 38712164PMCID: PMC11071490DOI
With Se-In Lee · Postdoc mentee
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Neuron · 2024
LGLi GanCLChloe Lopez-LeeGKGillian K CarlingLFLi FanNFNessa Foxe+9 more →
PMID: 39353433PMCID: PMC11624100DOI68 citations
With Chloe Lopez-Lee · Neuroscience · Class of 2024
Cellular and pathological functions of tau.
Nature reviews. Molecular cell biology · 2024
LGLi Gan SNSarah NaguibCPCeleste Parra Bravo
PMID: 39014245DOI205 citations
With Sarah Naguib · Postdoc mentee
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Cell · 2024
LGLi Gan YWYuansong WanCPCeleste Parra BravoAMAlice Maria GianiAJAvi J Samelson+7 more →
PMID: 38582079PMCID: PMC11365117DOI60 citations
With Yuansong Wan · Postdoc mentee
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Cell · 2024
LGLi GanAMAlice Maria GianiCPCeleste Parra BravoYWYuansong WanAJAvi J Samelson+7 more →
PMID: 38582079PMCID: PMC11365117DOI60 citations
With Alice Giani · Postdoc mentee
Mechanisms of sex differences in Alzheimer's disease.
Neuron · 2024
LGLi GanCLChloe Lopez-LeeEREileen Ruth S TorresGCGillian Carling
PMID: 38402606PMCID: PMC11076015DOI332 citations
With Chloe Lopez-Lee · Neuroscience · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Research square · 2023
LGLi GanCLChloe Lopez-LeeHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961627PMCID: PMC10635319DOI
With Chloe Lopez-Lee · Neuroscience · Class of 2024
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
bioRxiv : the preprint server for biology · 2023
LGLi GanCLChloe Lopez-LeeHCHao Chen LFLi Fan+5 more →WLWenjie Luo
PMID: 37961594PMCID: PMC10634844DOI
With Chloe Lopez-Lee · Neuroscience · Class of 2024
Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging.
bioRxiv : the preprint server for biology · 2023
LGLi GanCLChloe Lopez-LeeLFLi FanNFNessa FoxeEREileen Ruth Torres+1 more →
PMID: 37781600PMCID: PMC10541118DOI
With Chloe Lopez-Lee · Neuroscience · Class of 2024
The AD odyssey 2023: Tales of single cell.
Cell · 2023
LGLi Gan WQWenhui Qu WLWenjie Luo
PMID: 37774675DOI10 citations
With Wenhui Qu · Postdoc mentee
Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
bioRxiv : the preprint server for biology · 2023
LGLi GanAMAlice Maria GianiCPCeleste Parra BravoZZZeping ZhaoAEAlessandro Evangelisti+6 more →
PMID: 37745431PMCID: PMC10516028DOI
With Alice Giani · Postdoc mentee
Sex Differences in Neurodegeneration: The Role of the Immune System in Humans.
Biological psychiatry · 2021
LGLi GanCLChloe Lopez-Lee
PMID: 33715827PMCID: PMC8263798DOI52 citations
With Chloe Lopez-Lee · Neuroscience · Class of 2024