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Jill Roberts Institute for Research in Inflammatory Bowel Disease

Innate and adaptive immunity in chronic disease, autoimmune mechanisms, and immunotherapy development.

Top research areas

Immunology & Inflammation90 Cell & Molecular Biology88 Gastroenterology, Hepatology & Pancreatic Disease79

9 scholars653 publications

Spotlight

Microbiome Research

FWFangzhao Wang LXLeyi Xiao CGChun-Jun Guo

Nature biotechnology · 2026

Cell & Molecular Biology

YSYuhua Shi CYChongbo Yang SMSushmita Mukherjee LLLauretta Lacko JMJulie Magarian Blander

Nature · 2026

Immunology & Inflammation

LKLan Kang JZJordan Zhou RSRobbyn Sockolow GFGregory Field Sonnenberg

Nature · 2022

View all 653 publications →

Scholars9 Publications653 Grants63

Showing 1–20 of 653 publications

Colorectal cancers with distinct metastatic potential trigger divergent early T cell responses.
ARAfsana RahmanSCSebastian Carrasco NGNorihiro Goto
The Journal of experimental medicine · 2026
Omics-scale capture of electrophilic metabolites.
CPChristopher Parkhurst DADavid Artis
bioRxiv : the preprint server for biology · 2026
Editorial Expression of Concern: Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
RLRandy Longman
Nature · 2026
Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions.
DADavid Artis
Nature immunology · 2026
Omics-Scale Capture of Electrophilic Metabolites.
CPChristopher Parkhurst DADavid Artis
ACS chemical biology · 2026
Fibroblasts restrain gut inflammation by IGF1-dependent regulation of innate lymphocytes.
LKLan Kang GFGregory Field Sonnenberg
Science (New York, N.Y.) · 2026
Persistence of mucosal CAR-T cells and inflammatory remodeling in enterocolitis associated with BCMA CAR-T cell therapy.
JCJennifer Claytor EPErika Patel BLBenjamin Langan Gordon MMMaximilian Merz RLRandy Longman
Nature medicine · 2026
Antifungal therapy improves microbiome dynamics in inflammatory bowel disease.
XPXiangyu Pan JMJamie Marino LFLars F Westblade RLRandy Longman+1 more →IDIliyan D Iliev
Nature medicine · 2026 · 2 citations
Transferable genetic toolsets for nonmodel gut Clostridia enable in vivo reversible control of metabolite production.
FWFangzhao Wang LXLeyi Xiao CGChun-Jun Guo
Nature biotechnology · 2026
Enterochromaffin cells as a cellular integration hub for cooperative microbial signaling to modulate gut serotonin and motility.
CGChun-Jun Guo
Proceedings of the National Academy of Sciences of the United States of America · 2026
Isoleucine and valine promote prostate cancer progression via propionyl-CoA-mediated cholesterol metabolism.
ZLZhongchi Li LXLeyi Xiao XCXuanrong ChenJOJude Owiredu+8 more →JBJohn Blenis
Nature metabolism · 2026
Emerging insights into TL1A biology may guide precision therapy for IBD.
SPSilvia Pires WYWei Yang RLRandy Longman
The Journal of experimental medicine · 2026
Emergency granulopoiesis and innate immune memory in inflammatory bowel disease.
SPSilvia Pires RLRandy Longman
Trends in immunology · 2026 · 1 citations
Enteric Microbiome Features that Contribute to Gram-Negative Bloodstream Infections in Hematopoietic Cell Transplant Recipients Colonized with Fluoroquinolone-Resistant Enterobacterales.
GAGrace Anne Maldarelli JMJamie Marino JRJohn Richard Lee LFLars F Westblade+1 more →MSMichael Satlin
The Journal of infectious diseases · 2026
Gut microbe-derived short-chain fatty acids regulate alphavirus arthritis and macrophage activation in mice.
CGChun-Jun Guo
The Journal of clinical investigation · 2026 · 1 citations
Antigen-restricted Candida albicans Th17 cells link oral-gut immunity and adopt pathogenic features during intestinal inflammation.
XPXiangyu Pan IDIliyan D Iliev
Immunity · 2026 · 2 citations
Colorectal cancers with distinct metastatic potential trigger divergent early T cell responses.
ARAfsana RahmanSCSebastian Carrasco NGNorihiro Goto
bioRxiv : the preprint server for biology · 2026
Transcription factor BHLHE40 expression in group 3 innate lymphoid cells and RORγt⁺ antigen-presenting cells coordinates intestinal immunity.
WYWei Yang SPSilvia PiresECEmre CardakliDBDoron Betel RLRandy Longman
Immunity · 2026 · 1 citations
Chronic stress unleashes an intratumor phage-fibroblast-B cell circuit to promote tumor growth.
HBHilal BashirPRPurnima RavisankarSYShui YuHCHannah Carrow+5 more →MZMelody Zeng
Cancer cell · 2026 · 2 citations
Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis.
SGSaori Goto NGNorihiro Goto
Cell stem cell · 2026 · 2 citations

Jill Roberts Institute for Research in Inflammatory Bowel Disease

Transferable genetic toolsets for nonmodel gut Clostridia enable in vivo reversible control of metabolite production

Caspase 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis

ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut