CompletedObservationalNCT04890314 ↗Prostate Cancer - Comparative Outcomes of New Conceptual Paradigms for TreatmentJim C. HuPIInterventionOther: Patient-reported questionnaireDatesMay 2021 – Apr 2024
TerminatedObservationalNCT04926857 ↗DEFINE AFib Atrial Fibrillation - Development of a Predictive Model for Future Health Care Utilization From Measurements Collected From an Implantable Cardiac Monitor.Gioia TurittoPIInterventionOther: Non-InterventionalDatesJun 2021 – Jan 2024· Results postedSponsorMedtronic, Inc.Atrial Fibrillation
CompletedObservationalNCT04930666 ↗The Development and Pilot Testing of a Brief Shared Decision-Making Intervention to Improve Palliative Care Outcomes for Adults With Advanced Lung DiseaseRobert J. KanerPIInterventionOther: BRief intervention to Enhance Adherence to Treatment and HEalth advice in Advanced Lung DiseaseDatesNov 2021 – Feb 2025SponsorColumbia University Medical CenterPulmonary Disease, Chronic ObstructiveLung Diseases, Interstitial
CompletedObservationalNCT05004337 ↗Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies (VANISH)Jessica E. SchollPIDatesJul 2021 – Nov 2023SponsorNatera, Inc.Vanishing TwinTrisomy 21Trisomy 13+1 more
TerminatedObservationalNCT05008874 ↗Prospective, Retrospective, Multicenter, Observational Study of Disease Progression in Adults With Inherited Forms of Spastic ParaplegiaZuhal ErgonulPIInterventionOther: Natural History ObservationDatesJun 2021 – May 2025SponsorSwanBio Therapeutics LimitedAMNAMN Gene MutationX-ALD
CompletedObservationalNCT05074875 ↗Post COVID-19 Hypoxemic Respiratory Failure Residual Pathophysiologic OutcomesRobert J. KanerPIInterventionOther: Questionnaires and Patient Reported Outcomes (PROs) · Diagnostic test: Nasal Swab COVID-19 reverse transcription polymerase chain reaction test (RT-PCR) · Genetic: Blood Samples for Biomarkers · Diagnostic test: High Resolution Computed Tomography · Diagnostic test: Physical Exam and Vital Signs · Diagnostic test: Medical Research Council Sum Score · Diagnostic test: Hand Grip Strength · Diagnostic test: Spirometry · Diagnostic test: Diffusing Capacity of Carbon Monoxide · Diagnostic test: 6 Minute Walk Test · Diagnostic test: Sit to Stand (STS) MeasurementDatesJan 2021 – May 2023SponsorWeill Medical College of Cornell UniversityCovid19
CompletedObservationalNCT05172024 ↗NIH RECOVER: A Multi-site Observational Study of Post-Acute Sequelae of SARS-CoV-2 Infection in AdultsDaniel W SkupskiPIDatesOct 2021 – Oct 2025SponsorNYU LangoneSARS-CoV2 Infection
CompletedObservationalNCT05174338 ↗Cardiac Amyloidosis Registry Study - A Multi-Center, Longitudinal, Observational Survey of Patients With Cardiac AmyloidosisParag GoyalPIInterventionOther: RegistryDatesJan 2020 – Dec 2025 (est.)SponsorCedars-Sinai Medical CenterAmyloidosis, Immunoglobulin Light-chain
TerminatedObservationalNCT05224661 ↗Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse EventsAlexandra Gomez ArteagaPIInterventionOther: Prospective determination of the clinical utility of measurable residual disease (MRD) testingDatesAug 2022 – Dec 2025SponsorNational Marrow Donor ProgramAcute Myeloid Leukemia in Remission
CompletedObservationalNCT05255445 ↗Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (RBC-IMPACT)Melissa CushingPIInterventionBiological: Red Blood Cell (RBC) TransfusionDatesMar 2022 – Mar 2024SponsorNational Heart, Lung, & Blood InstituteSickle Cell DiseaseThalassemiaPediatric Cancer
CompletedObservationalNCT05345561 ↗A Prospective, Natural History Study to Assess the Occurrence of HPA-1a Alloimmunization in Women Identified at Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)Emilie Vander HaarPIDaniel W SkupskiPIInterventionOther: Clinical data collectionDatesMar 2022 – Jan 2025SponsorRallybio IPA, LLC.Fetal and Neonatal Alloimmune Thrombocytopenia
CompletedObservationalNCT05356546 ↗TYRX™ Pocket Health StudyJames E. IpPIInterventionOther: Study-required procedures include: tissue collection from device capsule, questionnaire collection, and photo collectionDatesMay 2022 – Jul 2023SponsorMedtronic Vascular, Inc.Cardiac DiseaseHealing Surgical Wounds
TerminatedObservationalNCT05780736 ↗Prospective Evaluation of Nivolumab in Adjuvant Esophageal Carcinoma/Gastroesophageal Junction Carcinoma: A Non-interventional StudyManish A ShahPIDatesAug 2023 – Aug 2024SponsorBristol-Myers Squibb CompanyEsophageal CarcinomaGastroesophageal Junction Carcinoma
CompletedObservationalNCT05835219 ↗REBYOTA™ for the Prevention of Recurrence of Clostridioides Difficile Infection (CDI) in Adult Patients: An Observational StudyCarl V. CrawfordPIInterventionDrug: REBYOTA™DatesJun 2023 – Aug 2025SponsorFerring Pharmaceuticals, Inc.Recurrence of Clostridium Difficile Infection
CompletedObservationalNCT05977933 ↗Assessing the Utility of Shape Submaximal Cardiopulmonary Exercise Testing in Detecting, Diagnosis and Treatment Management of Pulmonary Arterial Hypertension.Evelyn M. HornPIInterventionDevice: Shape II CPETDatesApr 2024 – Sep 2024 (est.)SponsorSHAPE MEDICAL SYSTEMS, INC.Pulmonary Arterial Hypertension
CompletedObservationalNCT05981495 ↗Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis DiseaseNishant PrasadPIInterventionDevice: NanoDetect-TBDatesAug 2023 – Dec 2024 (est.)SponsorNanoPin Technologies, Inc.Tuberculosis, PulmonaryTuberculosis, ExtrapulmonaryTuberculosis Active
TerminatedObservationalNCT06045923 ↗Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIVMarshall J. GlesbyPIDatesMar 2023 – Jan 2026SponsorCenters for Disease Control & PreventionMonkeypoxHIV InfectionsAIDS
TerminatedObservationalNCT06092970 ↗Clinical Protocol REN-007E - Extension Study: An Evaluation of Patient Reported Outcomes and Clinical Outcomes Through 12 Months Post-Cardiac Surgery in Subjects Enrolled in Study REN-007Charles Anthony MackPIInterventionDrug: RBT-1 · Drug: PlaceboDatesOct 2023 – Feb 2026SponsorRenibus Therapeutics, Inc.Post-Operative Complications in Cardiac Surgery
CompletedObservationalNCT06122961 ↗Prevalence of Systemic Inflammation in Patients With Atherosclerotic Cardiovascular Disease and Heart FailureSamuel KimPIInterventionOther: No treatment givenDatesNov 2023 – Apr 2025SponsorNovo Nordisk Pharmaceuticals, Inc.Cardiovascular RiskHeart FailureChronic Kidney Disease
CompletedObservationalNCT06152276 ↗SafeHeal Diverting Ileostomy Pivotal Study (SH-SOC23)Mehraneh Dorna JafariPIInterventionOther: Diverting loop ileostomyDatesJan 2024 – Jan 2026SponsorSafeHeal IncColorectal CancerStoma Ileostomy