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Scholars @ Weill Cornell Medicine

Help & supportPhase 1 prototype

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Scholars8,800 Publications201,349 Funding7,267 Clinical research52

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Browse

Scholars8,800 Publications201,349 Funding7,267 Clinical research52

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Status

Completed52
Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Terminated11

Study type

Interventional44
Observational8

Phase

Not applicable34
Not reported8
Phase 24
Phase 33
Phase 42
Phase 2/31

Investigator

James E. Ip4
Christopher F Liu3
Daniel W Skupski3
Jim W. Cheung3
Benjamin Samstein3

Department

Medicine28
Surgery6
Anesthesiology3
Neurology3
Obstetrics and Gynecology3

Show all 11

Condition

Atrial Fibrillation6
Bradycardia3
Liver Diseases3
Blood Loss, Surgical2
Chronic Pain2

Intervention type

Device52
Drug253
Other65
Biological42
Behavioral25
Procedure13

Sponsor type

Industry41
Other academic5
WCM (investigator-initiated)4
Cooperative group1
NIH1

Start date

Has results posted31

Completed×Device×Clear all

Showing 1–20 of 52 studiesSort:

CompletedInterventional · Not applicableNCT01816776 ↗
A Randomized Trial Evaluating the Safety and Effectiveness of the remedē® System in Patients With Central Sleep Apnea

FiltersClear all

Status

Completed52
Recruiting69
Not yet recruiting3
Enrolling by invitation5
Active, not recruiting50
Terminated11

Study type

Interventional44
Observational8

Phase

Not applicable34
Not reported8
Phase 24
Phase 33
Phase 42
Phase 2/31

Investigator

James E. Ip4
Christopher F Liu3
Daniel W Skupski3
Jim W. Cheung3
Benjamin Samstein3

Department

Medicine28
Surgery6
Anesthesiology3
Neurology3
Obstetrics and Gynecology3

Show all 11

Condition

Atrial Fibrillation6
Bradycardia3
Liver Diseases3
Blood Loss, Surgical2
Chronic Pain2

Intervention type

Device52
Drug253
Other65
Biological42
Behavioral25
Procedure13

Sponsor type

Industry41
Other academic5
WCM (investigator-initiated)4
Cooperative group1
NIH1

Start date

Has results posted31

Completed×Device×Clear all

Showing 1–20 of 52 studiesSort:

CompletedInterventional · Not applicableNCT01816776 ↗
A Randomized Trial Evaluating the Safety and Effectiveness of the remedē® System in Patients With Central Sleep Apnea

Show all 37

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Neel Mehta2
Reem Z. Sharaiha2
Shing Chiu Wong2
Shari Lipner2
Steven M Markowitz2
Asad Riaz Siddiqi1
Brian DeRubertis1
Bradley B Pua1
David Leslie Carr-Locke1
Faith Gunning1
Geoffrey W Bergman1
Gioia Turitto1
Grant Ellsworth1
Harini Sarva1
Hugh C Hemmings1
Higinia Cardenes1
Evelyn M. Horn1
Irina Sobol1
Jared Knopman1
Joel Stein1
Jai S. Perumal1
Lisa K Torres1
Nishant Prasad1
Peter Connolly1
Randy Longman1
Rajiv S. Magge1
Rajeev Dayal1
Reema Bhatt1
Seth H. Goldbarg1
Shmuel Chen1
Timothy McClure1
Vandana Sood1

Show fewer

Dermatology2
Radiology2
Rehabilitation Medicine2
Neurological Surgery1
Psychiatry1
Radiation Oncology1

Show all 50

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Heart Failure2
Nail Diseases2
Acute Coronary Syndrome1
Angina Pectoris1
Aortic Aneurysm, Thoracoabdominal1
Arrhythmias, Cardiac1
Atrioventricular Block1
Blood Coagulation Disorders1
Bundle-Branch Block1
COVID-191
Cardiomyopathies1
Cognitive Dysfunction1
Colitis, Ulcerative1
Coronary Artery Disease1
Coronary Stenosis1
Death, Sudden, Cardiac1
Familial Primary Pulmonary Hypertension1
Fatigue1
Fatty Liver1
Gallbladder Diseases1
Gastric Outlet Obstruction1
Gliosarcoma1
HIV Seropositivity1
Heart Valve Diseases1
Hematoma, Subdural1
Hypertension, Portal1
Ischemic Stroke1
Liver Cirrhosis1
Lung Neoplasms1
Multiple Sclerosis1
Myocardial Ischemia1
Neoplasms1
Parkinson Disease1
Pelvic Organ Prolapse1
Peripheral Arterial Disease1
Postpartum Hemorrhage1
Prostatic Neoplasms1
Pulmonary Arterial Hypertension1
Recurrence1
Respiratory Aspiration1
Severe combined immunodeficiency with sensitivity to ionizing radiation1
Shoulder Pain1
Sleep Apnea Syndromes1
Sleep Apnea, Central1
Sleep Wake Disorders1

Intervention: Device: Treatment Group (transvenous stimulation of the phrenic nerve) · Device: Control Group (Optimal Medical Therapy)
Dates: Mar 2013 – Sep 2016· Results posted
Sponsor: Respicardia, Inc

Sleep Apnea, CentralSleep Disordered BreathingHeart Failure

CompletedInterventional · Not applicableNCT02030418 ↗

The LEADLESS II IDE Study (Phase I): Safety and Effectiveness Trial for the Nanostim Leadless Pacemaker

James E. IpPI

Intervention: Device: Leadless Pacemaker
Dates: Feb 2014 – Jun 2015· Results posted
Sponsor: St. Jude Medical Foundation

Bradycardia

CompletedObservationalNCT02379104 ↗

ROTEM® Sigma Performance Evaluation - Method Comparison With Predicate Device and Reference Intervals

Hugh C HemmingsPI

Intervention: Device: ROTEM sigma
Dates: Oct 2017 – Oct 2018 (est.)
Sponsor: Instrumentation Laboratory

Blood Coagulation Disorders

CompletedInterventional · Phase 3NCT02518594 ↗

A Randomized Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix

Daniel W SkupskiPI

Intervention: Drug: Vaginal progesterone · Drug: Placebo · Device: Arabin Pessary
Dates: Nov 2015 – Dec 2024· Results posted
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Develop

Short Cervical Length

CompletedInterventional · Not applicableNCT02528500 ↗

Early Feasibility Assessment of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Type IV Thoracoabdominal Aortic Aneurysms Involving the Visceral Branch Vessels

Peter ConnollyPI

Intervention: Device: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis
Dates: Nov 2015 – May 2016· Results posted
Sponsor: W.L. Gore & Associates, Inc.

Thoracoabdominal Aortic Aneurysm

CompletedInterventional · Not applicableNCT03192696 ↗

INSIGHT: EvaluatIoN of the PantheriS OCT- ImaGing AtHerectomy SysTem For Treatment of In-Stent Restenosis (ISR) Lesions In Lower Extremity Arteries

Rajeev DayalPI

Intervention: Device: Atherectomy Catheter
Dates: Oct 2017 – Jun 2021
Sponsor: Avinger, Inc.

Peripheral Arterial Disease

CompletedInterventional · Not applicableNCT03259763 ↗

EUS-guided Gastroenterostomy Versus Enteral Stenting for Palliation of Malignant Gastric Outlet Obstruction: A Randomized Clinical Trial

Reem Z. SharaihaPI

Intervention: Device: Lumen-apposing metal stent · Device: Self-expandable metal stent
Dates: Oct 2020 – Jun 2025· Results posted
Sponsor: The Johns Hopkins University

Gastric Outlet Obstruction

CompletedInterventional · Phase 3NCT03377491 ↗

Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma

Higinia CardenesPI

Intervention: Device: NovoTTF-200T · Drug: Gemcitabine · Drug: nab paclitaxel
Dates: May 2018 – Oct 2024· Results posted
Sponsor: Novocure, Ltd.

Pancreas Adenocarcinoma

CompletedInterventional · Phase 2NCT03603808 ↗

A Phase 2 Evaluation of VGX-3100, a Synthetic DNA Immunotherapy Targeting Human Papillomavirus 16 and 18 E6 and E7 Proteins, for Anal High-Grade Squamous Intraepithelial Lesions (HSIL) in HIV-Positive Individuals

Grant EllsworthPI

Intervention: Device: Electroporation · Biological: HPV DNA Plasmids Therapeutic Vaccine VGX-3100 · Other: Laboratory Biomarker Analysis
Dates: Sep 2018 – Dec 2024· Results posted
Sponsor: AIDS Malignancy Consortium

Anal Intraepithelial NeoplasiaHigh Grade Squamous Intraepithelial NeoplasiaHIV Positivity+2 more

CompletedInterventional · Not applicableNCT03775512 ↗

Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation (PVI) in Subjects With PAF

Christopher F LiuPI

Intervention: Device: RF Ablation with QDOT Micro
Dates: Jan 2019 – Feb 2022· Results posted
Sponsor: Biosense Webster, Inc.

Paroxysmal Atrial Fibrillation

CompletedInterventional · Not applicableNCT03973281 ↗

A Randomized, Controlled Study to Evaluate the Safety and Effectiveness of the Materna Prep Device to Pre-stretch the Vaginal Canal and Pelvic Floor Tissues in Preparation for Vaginal Delivery

Daniel W SkupskiPI

Intervention: Device: Materna Prep Device · Other: Standard of Care (SOC)
Dates: Dec 2019 – Jul 2026
Sponsor: Materna Medical

Vaginal DeliveryPelvic Organ Prolapse

CompletedInterventional · Not applicableNCT04060680 ↗

Extravascular ICD Pivotal Study (EV ICD)

Jim W. CheungPI

Intervention: Device: Defibrillation using the Extravascular ICD
Dates: Sep 2019 – Apr 2022· Results posted
Sponsor: Medtronic, Inc.

TachycardiaVentricular Arrythmia

CompletedInterventional · Not applicableNCT04103749 ↗

Global Prospective Case Series Using a Single-Use Duodenoscope

David Leslie Carr-LockePI

Intervention: Device: Exalt Model D Single-Use Duodenoscope
Dates: Mar 2021 – Nov 2022· Results posted
Sponsor: Boston Scientific Corporation

Endoscopic Retrograde Cholangiopancreatography

CompletedObservationalNCT04175626 ↗

BIOTRONIK - A Prospective Multicenter Study to Confirm the SaFety and Effectiveness of the Orsiro SiroLimus Eluting Coronary Stent System in the Treatment Of Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions - VII

Geoffrey W BergmanPI

Intervention: Device: Orsiro DES
Dates: Jan 2020 – Jan 2022· Results posted
Sponsor: BIOTRONIK GmbH & Co.

Coronary Artery DiseaseAtherosclerosis, CoronaryMyocardial Ischemia+3 more

CompletedObservationalNCT04281160 ↗

Patient Centered Outcomes Analysis for MS Using a Mobile Application

Jai S. PerumalPI

Intervention: Device: BeCare Mobile App
Dates: Feb 2020 – Sep 2023 (est.)
Sponsor: Weill Medical College of Cornell University

Multiple Sclerosis

CompletedInterventional · Not applicableNCT04291014 ↗

A Dose Selection Trial of Light Therapy for Impaired Sleep in Parkinson's Disease

Harini SarvaPI

Intervention: Device: SunRay Light Boxes
Dates: Sep 2020 – Nov 2022· Results posted
Sponsor: The General Hospital Corporation (dba Massachusetts General Hospital)

Parkinson DiseaseSleep DisorderFatigue

CompletedObservationalNCT04370691 ↗

JET Enhanced Thrombectomy Intervention Registry - JETi Registry

Brian DeRubertisPI

Intervention: Device: JETi lower extremity arterial thrombosis
Dates: Mar 2020 – Jan 2024· Results posted
Sponsor: Abbott Cardiovascular Systems, Inc.

Arterial Thrombosis

CompletedInterventional · Phase 2/3NCT04396860 ↗

A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab Versus Temozolomide in Patients With Newly Diagnosed MGMT (Tumor O-6-Methylguanine DNA Methyltransferase) Unmethylated Glioblastoma

Rajiv S. MaggePI

Intervention: Procedure: Contrast-enhanced Magnetic Resonance Imaging · Biological: Ipilimumab · Biological: Nivolumab · Device: NovoTTF-100A Device · Other: Quality-of-Life Assessment · Other: Questionnaire Administration · Radiation: Radiation Therapy · Drug: Temozolomide
Dates: Sep 2020 – Jan 2023· Results posted
Sponsor: NRG Oncology

GliosarcomaMGMT-Unmethylated Glioblastoma

CompletedInterventional · Not applicableNCT04402632 ↗

A Study of the Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System In the Treatment of Subacute and Chronic Subdural HEmatoma (EMBOLISE)

Jared KnopmanPI

Intervention: Procedure: Surgical Management · Device: Onyx™ Liquid Embolic System (LES) Embolization · Other: Observation Only
Dates: Oct 2020 – Dec 2024
Sponsor: Medtronic, Inc.

Subdural Hematoma

CompletedInterventional · Phase 4NCT04422795 ↗

The Evaluation of External Thermomechanical Stimulation for Pain Reduction in Patients Undergoing Nail Injection

Shari LipnerPI

Intervention: Device: External thermomechanical device delivering cold and vibration stimuli · Device: External thermomechanical device without delivering cold and vibration stimuli · Drug: Ethyl chloride skin refrigerant spray
Dates: Feb 2024 – Feb 2025 (est.)
Sponsor: Weill Medical College of Cornell University

Nail Diseases

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