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Scholars @ Weill Cornell Medicine

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Scholars8,803 Publications201,993 Funding7,268 Clinical research27

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Browse

Scholars8,803 Publications201,993 Funding7,268 Clinical research27

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Status

Recruiting8
Active, not recruiting8
Completed8
Terminated3

Study type

Interventional23
Observational4

Phase

Not applicable17
Phase 35
Not reported4
Phase 21

Investigator

Jim W. Cheung6
Christopher F Liu4
James E. Ip3
Gioia Turitto2
Hooman Kamel2

Show all 15Show fewer

Department

Medicine22
Cardiothoracic Surgery3
Neurology2

Condition

Atrial Fibrillation27
Prostatic Neoplasms52
Leukemia, Myeloid, Acute50
Breast Neoplasms43
Heart Failure34

Show all 50

Intervention type

Device19
Drug8
Other3
Procedure2

Sponsor type

Industry20
Other academic6
WCM (investigator-initiated)1

Start date

Has results posted7

Atrial Fibrillation×Clear all

Showing 1–20 of 27 studiesSort:

Active, not recruitingInterventional · Not applicableNCT03732794 ↗
AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment During Concomitant On-Pump Endo/Epicardial Cardiac Surgery
Leonard N GirardiPI
Intervention
Device: AtriCure CryoICE & AtriClip LAA Exclusion
Dates
Jan 2019 – Jun 2024

FiltersClear all

Status

Recruiting8
Active, not recruiting8
Completed8
Terminated3

Study type

Interventional23
Observational4

Phase

Not applicable17
Phase 35
Not reported4
Phase 21

Investigator

Jim W. Cheung6
Christopher F Liu4
James E. Ip3
Gioia Turitto2
Hooman Kamel2

Show all 15Show fewer

Department

Medicine22
Cardiothoracic Surgery3
Neurology2

Condition

Atrial Fibrillation27
Prostatic Neoplasms52
Leukemia, Myeloid, Acute50
Breast Neoplasms43
Heart Failure34

Show all 50

Intervention type

Device19
Drug8
Other3
Procedure2

Sponsor type

Industry20
Other academic6
WCM (investigator-initiated)1

Start date

Has results posted7

Atrial Fibrillation×Clear all

Showing 1–20 of 27 studiesSort:

Active, not recruitingInterventional · Not applicableNCT03732794 ↗
AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment During Concomitant On-Pump Endo/Epicardial Cardiac Surgery
Leonard N GirardiPI
Intervention
Device: AtriCure CryoICE & AtriClip LAA Exclusion
Dates
Jan 2019 – Jun 2024

Seth H. Goldbarg2
Steven M Markowitz2
David J Slotwiner1
Geoffrey W Bergman1
George Thomas1
Joonhyuk Kim1
Leonard N Girardi1
Eilon Ram1
Maryna Skliut1
Mario Fl Gaudino1

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Multiple Myeloma32
Neoplasms32
Colitis, Ulcerative29
Carcinoma, Non-Small-Cell Lung27
Crohn Disease27
Recurrence27
COVID-1926
Myelodysplastic Syndromes26
Parkinson Disease24
Neoplasm Metastasis23
Obesity23
Colorectal Neoplasms19
HIV Infections19
Hematologic Neoplasms19
Cardiovascular Diseases18
Depression18
Non-alcoholic Fatty Liver Disease16
Overweight15
Lung Neoplasms14
Melanoma14
Cognitive Dysfunction13
Idiopathic Pulmonary Fibrosis13
Inflammatory Bowel Diseases13
Alzheimer Disease12
Leukemia12
Leukemia, Lymphocytic, Chronic, B-Cell12
Lymphoma, Non-Hodgkin12
Primary Myelofibrosis12
Coronary Artery Disease11
Hypertension11
Hypertension, Pulmonary11
Lung Diseases, Interstitial11
Myeloproliferative Disorders11
Pulmonary Arterial Hypertension11
Stroke11
Chronic Pain10
Hemophilia A10
Leukemia, Myelomonocytic, Chronic10
Lymphoma, Follicular10
Lymphoma, Large B-Cell, Diffuse10
Urinary Bladder Neoplasms10
Burkitt Lymphoma9
Fibrosis9
Liver Diseases9
Carcinoma, Renal Cell8

Sponsor

AtriCure, Inc.

Atrial Fibrillation (AF)Persistent Atrial FibrillationLongstanding Persistent Atrial Fibrillation

RecruitingInterventional · Phase 3NCT03907046 ↗

Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery

Maryna SkliutPIHooman KamelPI

Intervention: Drug: Apixaban · Drug: Aspirin
Dates: Jan 2020 – Apr 2027 (est.)
Sponsor: Yale University

Intracerebral HemorrhageAtrial Fibrillation

Active, not recruitingInterventional · Not applicableNCT04226547 ↗

Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants

Geoffrey W BergmanPI

Intervention: Device: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder) · Drug: Non-Vitamin K Oral Antagonists
Dates: Jul 2020 – Jan 2029 (est.)
Sponsor: Abbott Cardiovascular Systems, Inc.

Atrial FibrillationStrokeBleeding

Active, not recruitingInterventional · Not applicableNCT04818645 ↗

Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients (ASSERT-AF)

Gioia TurittoPI

Intervention: Device: ASSERT Insertable Cardiac Monitor · Other: Conventional Management and monitoring
Dates: Jan 2023 – Jul 2028 (est.)
Sponsor: University of Rochester

Atrial FibrillationHeart Failure

RecruitingInterventional · Not applicableNCT05723926 ↗

Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

Hooman KamelPI

Intervention: Device: Vine Filter
Dates: Jan 2026 – Dec 2028 (est.)
Sponsor: Javelin Medical Ltd.

Atrial FibrillationOral AnticoagulationStroke+1 more

Active, not recruitingInterventional · Phase 3NCT05757869 ↗

A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, Versus Apixaban in Participants With Atrial Fibrillation

Steven M MarkowitzPI

Intervention: Drug: Milvexian · Drug: Apixaban · Drug: Placebo · Drug: Apixaban Placebo
Dates: Apr 2023 – Dec 2026 (est.)
Sponsor: Janssen Research & Development, LLC

Atrial Fibrillation

RecruitingInterventional · Phase 3NCT05836987 ↗

REACT-AF: Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Jim W. CheungPIJoonhyuk KimPI

Intervention: Device: AFSW Guided DOAC · Drug: Continuous DOAC therapy
Dates: Jul 2023 – Jul 2029 (est.)
Sponsor: Northwestern University Feinberg School of Medicine

Atrial Fibrillation

RecruitingInterventional · Not applicableNCT05963698 ↗

The Fourth Left Atrial Appendage Occlusion Study (LAAOS-4)

Christopher F LiuPI

Intervention: Device: WATCHMAN device
Dates: Nov 2023 – Sep 2029 (est.)
Sponsor: Population Health Research Institute

Atrial FibrillationStroke, IschemicSystemic Embolism

RecruitingObservationalNCT06056271 ↗

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

Seth H. GoldbargPI

Intervention: Device: AF Ablation
Dates: Mar 2024 – Dec 2027 (est.)
Sponsor: Volta Medical

Atrial Fibrillation

Active, not recruitingInterventional · Not applicableNCT06096337 ↗

A Prospective Randomized Multicenter Global Study Comparing Pulsed Field Ablation (PFA) Versus Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation

Jim W. CheungPI

Intervention: Device: FARAPULSE™ Pulsed Field Ablation (PFA) System · Drug: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Dates: Dec 2023 – Feb 2026
Sponsor: Boston Scientific Corporation

Persistent Atrial Fibrillation

Active, not recruitingObservationalNCT06431815 ↗

Prospective, Multi-site Safety and Effectiveness Post-Approval Study of FARAPULSE Pulsed Field Ablation in Paroxysmal Atrial Fibrillation

David J SlotwinerPI

Intervention: Device: FARAPULSE™ Pulsed Field Ablation System
Dates: Sep 2024 – Oct 2028 (est.)
Sponsor: Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

Active, not recruitingInterventional · Not applicableNCT06455098 ↗

Assessment of Safety and Effectiveness in Treatment Management of Paroxysmal Atrial Fibrillation With the BWI Pulsed Field Ablation System With OMNYPULSE™ Catheter

Christopher F LiuPI

Intervention: Device: OMNYPULSE™ Catheter with the TRUPULSE Generator
Dates: Jun 2024 – Jul 2027 (est.)
Sponsor: Biosense Webster, Inc.

Atrial Fibrillation

RecruitingInterventional · Not applicableNCT06486636 ↗

Pericardiotomy in Cardiac Surgery Trial

Mario Fl GaudinoPI

Intervention: Procedure: Left Posterior Pericardiotomy
Dates: Oct 2024 – Sep 2027 (est.)
Sponsor: Hamilton Health Sciences Corporation

Atrial FibrillationAtrial FlutterCardiac Events

RecruitingInterventional · Phase 3NCT06716021 ↗

Multi-Center, Placebo-Controlled, Phase 3 Study of Etripamil Nasal Spray (NS) in Patients With Atrial Fibrillation and Rapid Ventricular Rate (RVR)

James E. IpPI

Intervention: Drug: Placebo · Drug: Etripamil
Dates: Aug 2026 – Dec 2028 (est.)
Sponsor: Milestone Pharmaceuticals

Atrial Fibrillation

Active, not recruitingInterventional · Not applicableNCT06735534 ↗

The ReMATCH Study is a Prospective, Single Arm, Open Label, Multi-center, Study Utilizing the FARAPULSE PFA System, Including the FARAWAVE and FARAPOINT PFA Catheters

Jim W. CheungPI

Intervention: Device: FARAPULSE™ Pulsed Field Ablation System
Dates: Jun 2025 – Apr 2027 (est.)
Sponsor: Boston Scientific Corporation

Persistent Atrial Fibrillation

RecruitingInterventional · Not applicableNCT06959121 ↗

Pulse Biosciences' CellFX nsPFA Cardiac Surgery Clamp System for the Treatment of Atrial Fibrillation During Concomitant Cardiac Surgery

Eilon RamPI

Intervention: Device: CellFX® nsPFA™ Cardiac Surgery System
Dates: Oct 2025 – Apr 2027 (est.)
Sponsor: Pulse Biosciences INC

Atrial FibrillationMaze ProcedureAF+1 more

CompletedInterventional · Phase 2NCT03539302 ↗

A Prospective Randomized Multicenter Study of Flecainide Acetate Oral Inhalation Solution in Single and Repeat Dose Regimens for Acute Conversion to Sinus Rhythm in Subjects With Recent Onset of Symptomatic Paroxysmal Atrial Fibrillation

James E. IpPI

Intervention: Drug: Flecainide Acetate
Dates: May 2018 – Jan 2022· Results posted
Sponsor: InCarda Therapeutics

Paroxysmal Atrial Fibrillation (PAF)

CompletedInterventional · Not applicableNCT03775512 ↗

Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation (PVI) in Subjects With PAF

Christopher F LiuPI

Intervention: Device: RF Ablation with QDOT Micro
Dates: Jan 2019 – Feb 2022· Results posted
Sponsor: Biosense Webster, Inc.

Paroxysmal Atrial Fibrillation

CompletedInterventional · Not applicableNCT04170894 ↗

Radiofrequency Ablation of Atrial Fibrillation Under Apnea

Jim W. CheungPI

Intervention: Other: Periods of Apnea · Other: Control Arm - No Periods of Apnea
Dates: Oct 2020 – Mar 2022
Sponsor: Weill Medical College of Cornell University

Atrial Fibrillation

CompletedInterventional · Not applicableNCT04580914 ↗

Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation

Jim W. CheungPI

Intervention: Device: Treatment with IntellaNav StablePoint Ablation Catheter
Dates: Apr 2021 – Jun 2023· Results posted
Sponsor: Boston Scientific Corporation

Paroxysmal Atrial Fibrillation

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