Highlights
- 1The Journal of thoracic and cardiovascular surgery · 2023
- 2Lancet (London, England) · 2021
- 3
Publications
Funding
Active
16 grants- Sub-PISRI 261674-01Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts Extended Survival (ROMAES)Canadian Institutes of Health Research · 2026–2032 · via Sunnybrook Research Institute
- PIR01HL181504-01A1RECHARGE: IMAGING Ancillary Study (Non-invasive Coronary Imaging in Women and Minorities Referred for Multivessel Coronary Revascularization)NHLBI · 2026–2031 · via NIH RePORTER
- Co-IR01HL184552-01A1Improving External Validity of the RECHARGE Trial through a Partially Randomized Patient Preference FrameworkNational Heart, Lung, and Blood Institute · 2026–2031
- PIPLACER-2022C3-30048Revascularization Choices Among Under-Represented Groups Evaluation: The RECHARGE ProgramPatient-Centered Outcomes Research Institute · 2023–2030
- Sub-PICIHR 242260-01Subaward agreement ROMA Women TrialCanadian Institute of Health Research · 2023–2030 · via Sunnybrook Research Institute
- PIUH3HL169564-021/2 Randomized comparison of the Outcomes of single vs Multiple Arterial grafts trial in Women (ROMA:Women)National Heart, Lung, and Blood Institute · 2025–2030
- Co-IR01EB037051-01A1Transcranial Doppler array for automated ultrasound emboli detection with deep learningNational Institute of Biomedical Imaging and Bioengineering · 2026–2030
- Sub-PIOHIRC 233757-01“One-month Dapt In cabg patieNts: the ODIN trial”Canadian Institutes of Health Research · 2023–2029 · via Ottawa Heart Institute Research CorporationNo publications yet
- PISHT 224277-01The Canadian CABG or PCI in Patients with Ischemic Cardiomyopathy (STICH 3.0) Trial // Master AgreementSunnybrook Hospital, Toronto · 2022–2029
- MPIR01HL170566-04Cardiac Magnetic Resonance Tissue Characterization of Ischemic and Non-Ischemic Myocardium to Predict Left Ventricular Functional Recovery and Outcomes after Multivessel Coronary RevascularizationNational Heart, Lung, and Blood Institute · 2023–2028
- Sub-PI488058The One-Month DAPT with Ticagrelor In CABG PatieNts Trial (ODIN)Canadian Institutes of Health Research · 2022–2028 · via Ottawa Heart Institute Research Corporation
- MPIR01HL170570-01Towards Personalized Prosthetic Graft Replacement for Genetically Triggered Thoracic Aortic AneurysmsNational Heart, Lung, and Blood Institute · 2023–2028
- Sub-PIPJT-162085Randomized Comparison of the Outcome of Single Versus Multiple Arterial Grafts: ROMA Trial - Definitive PhaseCanadian Institute of Health Research · 2019–2027 · via Sunnybrook Hospital, Toronto
- Co-IR01HL151686-03S1Noninvasive measurement of oxygenation using quantitative susceptibility mapping (supplement)National Heart, Lung, and Blood Institute · 2023–2026
- PIR01HL152021-05Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)National Heart, Lung, and Blood Institute · 2020–2026
- Sub-PIR01NS123639-02Randomized Comparison of the Clinical Outcome of Single Versus Multiple Arterial Grafts: Cognition (ROMA:Cog)National Institute of Neurological Disorders and Stroke · 2021–2025 · via Columbia University· 2 renewals
Completed grants (3)
- Co-IU01FD006292-03Real-World Clinical Outcomes in Patients with Mechanical Heart Valve Replacement and Anticoagulation VariabilityUnited States Food & Drug Administration · 2019–2020 · via Vanderbilt University Medical Center
- Sub-PISHT 392185Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: the ROMA trialCanadian Institute of Health Research · 2018–2020 · via Sunnybrook Hospital, Toronto
- Co-IU01HL125506-03Hybrid Coronary Revascularization Trial- DCCNational Heart, Lung, and Blood Institute · 2018–2019 · via Icahn School of Medicine at Mount Sinai
Clinical research
Active
8 studies- PINCT07485738Surgical Measurement for Accurate Revascularization Using Transit-time FLOW (SMARTFLOW):PatencyNA · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)CABG Graft Integrity; CABG; Blood Flow; Transit-time Flow Measurement; Heart Disease
- PICoronary Artery Bypass Graft Surgery: CognitionWeill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
- PIBiodEgradable soaked Amiodarone paTch use for the prevention of Atrial Fibrillation after cardiac surgery (The BEAT-AF trial)Jilin Heart Hospital, China · OPEN TO ACCRUAL (as of 2025)
- PINCT06486636Pericardiotomy in Cardiac Surgery TrialNA · Hamilton Health Sciences Corporation · OPEN TO ACCRUAL (as of 2025)Atrial Fibrillation; Atrial Flutter; Cardiac Events
- PINCT05997693One Month Dual Antiplatelet Therapy With Ticagrelor in Coronary Artery Bypass Graft PatientsPHASE3 · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)Chronic Coronary Disease
- PINCT06399705REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - MinoritiesPHASE3 · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)Coronary Artery Disease
- PISTICH3C Cardiac Magnetic Resonance (CMR) Observational Study (STICOS)Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2023)
- PINCT05427370The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy TrialNA · Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2023)Coronary Artery Disease; Heart Failure Systolic
News mentions
- Bypass Surgery May Offer Greater Long-Term Benefits Compared with Stents for WomenDecember 22, 2025
Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.
- Awards & Honors: October 2025October 21, 2025
Awards, honors and achievements for the month of October.
- Anemia May Contribute to Higher Female Mortality During Heart SurgeryApril 11, 2024
Women are at higher risk of death when undergoing heart bypass surgery than men. Researchers at Weill Cornell Medicine have determined that this disparity is mediated, to a large extent, by intraoperative anemia—the dilution of red blood cells during surgery.
- Large PCORI Award Funds Comparative Study of Surgical Options for Coronary Artery Disease in Underrepresented Patient PopulationsJuly 25, 2023
A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery and assistant dean for clinical trials at Weill Cornell Medicine, has been approved for a nearly $30 million funding award from the Patient-Centered Outcomes Research Institute (PCORI).
- Nationwide Study Finds That Women Have Greater Risk of Mortality Than Men After Coronary Artery Bypass SurgeryMarch 6, 2023
Compared with men, women continue to have a roughly 30-40 percent higher risk of dying following coronary artery bypass surgery, according to a large study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center.
Show 7 more mentions
- Two-Medication Strategy Offers Both Benefit and Risk After Coronary Artery Bypass SurgeryAugust 9, 2022
A new analysis shows that a combination of two anti-platelets drugs can benefit patients after the most common type of cardiac surgery — while also increasing the risk of potentially dangerous bleeding.
- Simple Surgical Technique Associated with Significant Reduction in the Risk of Atrial Fibrillation After Cardiac SurgeryNovember 15, 2021
A simple surgical technique during cardiac surgery was associated with a 56 percent reduction in the incidence of an irregular heart rhythm known as atrial fibrillation that can lead to stroke, with no added risks or side effects, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators.
- Q&A with Dr. Mario Gaudino, Newly Appointed Director of the Joint Clinical Trials OfficeJanuary 29, 2021
For Dr. Mario Gaudino, being an excellent cardiothoracic surgeon and conducting clinical research to find new ways to improve patients’ outcomes have been two sides of the same coin since he was a medical student in Rome.
- Long-Term Outcomes After Coronary Artery Bypass Surgery Differ by SexDecember 23, 2020
The risk of dying seven years after coronary artery bypass surgery was significantly lower in men receiving multiple bypass grafts rather than single grafts, but there was no apparent difference in mortality between these methods in women.
- Study Helps Resolve Debate about How to Compare Heart Procedures in Clinical TrialsOctober 12, 2020
A long-standing debate among cardiologists comparing two common heart procedures is closer to being resolved.
- Method Using Artery for Coronary Artery Bypass Linked to Better Long-term Outcomes Than Using VeinJuly 14, 2020
One method for coronary artery bypass surgery is linked to a significantly lower risk of death, heart attack, or the need for a new surgery compared to the most commonly chosen one, according to an international study led by Weill Cornell Medicine and NewYork-Presbyterian heart surgeons.
- Type of Sponsorship Associated with Differences Between Trials for Invasive Cardiovascular TreatmentsJune 1, 2020
In randomized clinical trials, commercial sponsorship influences how studies are designed and the results reported in ways that often benefit the study’s sponsor, Weill Cornell Medicine and NewYork-Presbyterian investigators report.
Media highlights
- Mortality Similar With PCI, CABG In Left Main CAD In A Broad Asian PopulationTCTMD · November 4, 2026
Mentoring
- BBBrenden BrattonMD mentee · Class of 2023