Co-authored publications with mentees

PhD mentee

• SMARCA4, STK11, and KEAP1 co-inactivation associates with poor prognosis and upregulation of the TGF-β pathway in lung adenocarcinoma.

  Translational oncology · 2026

  CRCharles RudinCWCorrin WohlhieterJJJustin Jee

  PMID: 42476096·PMCID: PMC13392563·DOI·Abstract

  With Corrin Wohlhieter · Pharmacology (PhD) · Class of 2021

• Correction: SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.

  Journal of hematology & oncology · 2024

  CRCharles RudinVDVidushi DuraniJZJudy ZhongDBDoron Betel

  PMID: 39343962·PMCID: PMC11441257·DOI

  With Vidushi Durani · Cell & Developmental Biology (PhD)

• SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing.

  Journal of hematology & oncology · 2024

  CRCharles RudinVDVidushi DuraniDBDoron Betel

  PMID: 39080761·PMCID: PMC11290012·DOI·36 citations·Abstract

  With Vidushi Durani · Cell & Developmental Biology (PhD)

• CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation.

  Signal transduction and targeted therapy · 2024

  CRCharles RudinVDVidushi DuraniMSMoniquetta ShaferHAHelena Alexandra Yu

  PMID: 39054323·PMCID: PMC11272780·DOI·23 citations·Abstract

  With Vidushi Durani · Cell & Developmental Biology (PhD)

• Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.

  Science translational medicine · 2023

  CRCharles RudinVDVidushi DuraniMSMoniquetta ShaferCLCharles L. Sawyers

  PMID: 37531417·PMCID: PMC10777207·DOI·41 citations·Abstract

  With Vidushi Durani · Cell & Developmental Biology (PhD)

• Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity.

  Clinical cancer research : an official journal of the American Association for Cancer Research · 2022

  CRCharles RudinKMKathryn M TullyJAJoshua A KorsenAMAvelyn Mae Delos ReyesJSJason S. Lewis

  PMID: 35046060·PMCID: PMC8976830·DOI·67 citations·Abstract

  With Kathryn Tully · Pharmacology (PhD) · Class of 2021

• MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer.

  iScience · 2021

  CRCharles RudinVDVidushi DuraniECEmily Costa

  PMID: 34712921·PMCID: PMC8528729·DOI·28 citations·Abstract

  With Vidushi Durani · Cell & Developmental Biology (PhD)

• MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer.

  iScience · 2021

  CRCharles RudinECEmily CostaVDVidushi Durani

  PMID: 34712921·PMCID: PMC8528729·DOI·28 citations·Abstract

  With Emily Costa · Cell & Developmental Biology (PhD) · Class of 2024

• Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer.

  Cancer discovery · 2021

  CRCharles RudinEAEmily A CostaAVAndrea Ventura

  PMID: 34344693·PMCID: PMC8810895·DOI·38 citations·Abstract

  With Emily Costa · Cell & Developmental Biology (PhD) · Class of 2024

• Tim-4⁺ cavity-resident macrophages impair anti-tumor CD8⁺ T cell immunity.

  Cancer cell · 2021

  CRCharles RudinCWCorrin WohlhieterSSSara SchadDZDmitriy Zamarin+7 more →TMTaha Merghoub

  PMID: 34115989·PMCID: PMC9115604·DOI·172 citations·Abstract

  With Corrin Wohlhieter · Pharmacology (PhD) · Class of 2021

• An optimized NGS sample preparation protocol for in vitro CRISPR screens

  STAR Protocols · 2021

  Source: Scopus·DOI

  With Corrin Wohlhieter · Pharmacology (PhD) · Class of 2021

• Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics.

  Nature cancer · 2020

  CRCharles RudinEAEmily A Costa

  PMID: 33345196·PMCID: PMC7745982·DOI·38 citations·Abstract

  With Emily Costa · Cell & Developmental Biology (PhD) · Class of 2024

• Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer.

  Cell reports · 2020

  CRCharles RudinCACorrin A Wohlhieter

  PMID: 33264619·PMCID: PMC7722473·DOI·218 citations·Abstract

  With Corrin Wohlhieter · Pharmacology (PhD) · Class of 2021