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Highlights

  1. 1
    Scientific reports · 2023
    PMID: 37258519PMCID: PMC10232445DOISenior author37 citations
  2. 2
    Journal of the neurological sciences · 2024
    PMID: 38341949PMCID: PMC10947806DOISenior author7 citations
  3. 3
    Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    PMID: 35294075PMCID: PMC9308634DOIFirst author23 citations

Publications

136 publications

Active

12 grants
  • Co-I
    Understanding Psychosis Heterogeneity In Late Life (UPHILL)
    National Institute on Aging · 2026–2031
    R01AG096446-01A1
  • Co-I
    Circulating Antibody Repertoire And Blood-Brain-Barrier Impairment to explain NEuRopsychiatric symptoms of "invisible" brain injury
    U.S. Department of Defense · 2025–2029
    HT9425-25-1-0789
  • MPI
    Prism-PET/EMMT: High resolution, cost effective, portable, and upright brain PET scanner for early diagnosis of Alzheimer's disease
    National Institute on Aging · 2024–2029
    U01AG082845-01A1
  • Co-I
    Quantitative cerebral oxygen metabolic imaging of acute ischemic stroke
    National Institute of Neurological Disorders and Stroke · 2024–2029
    R01NS135205-01A1
  • MPI
    Tau progression index (TPI): An individualized predictor of Alzheimer's Disease trajectory based on subject-specific connectomes
    National Institute on Aging · 2024–2029
    R01AG085972-01A1
  • Co-I
    Brain fluid clearance and misfolded protein dynamics following traumatic brain injury
    National Institute on Aging · 2023–2029
    R01AG077576-01A1
  • MPI
    Quantitative MRI-based cerebral oxygen metabolism in Alzheimer's disease
    National Institute on Aging · 2023–2028
    R01AG080011-04
  • Co-I
    Gene Therapy for APOE4 Homozygous Alzheimer's Disease
    National Institute on Aging · 2026–2028
    UG3AG098024-01
  • Co-I
    Fluid mechanics approach to tissue perfusion quantification in MRI
    National Institute of Biomedical Imaging and Bioengineering · 2023–2027
    R01EB034755-01
  • PI
    The effects of iron on oxidative stress and Alzheimer's biomarkers in amyloid-positive and negative elderly normal
    National Institute on Aging · 2020–2027
    R01AG068398-05
  • PI
    SA Nexus
    Minoryx Therapeutics SL · 2022–2026Contract
    SA 224045-03
  • Co-I
    Innovative Methods for PHI-free Aggregation of CT Studies (IMPACTS)
    American Heart Association · 2024–2026 · via Yale University
    24GWTGSIC1341098
Completed grants (10)
  • Co-I
    Quantitative Susceptibility Mapping (QSM) as a Non-Invasive Imaging Biomarker for Predicting Neurodegeneration in Alzheimer's Disease
    National Institute on Aging · 2020–2025
    R21AG067466-01A1
  • KP
    7T Magnetic Resonance Imaging System for Basic, Translational and Clinical Research
    Office of the Director, NIH · 2021–2025
    S10OD027039-01A1
  • Co-I
    QSM to Guide Iron Chelating Therapy in Transfusional Iron Overload - Administrative Supplement
    National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2025
    R01DK116126-05S1
  • Co-I
    No-Gd MRI for Monitoring Disease Status in Multiple Sclerosis
    National Institute of Neurological Disorders and Stroke · 2018–2024
    R01NS105144-01A1
  • Co-I
    Predictive Model of Spread of Parkinson's Pathology Using Network Diffusion
    National Institute of Neurological Disorders and Stroke · 2016–2023
    R01NS092802-01A1
  • Sub-PI
    Clinical evaluation of a CT perfusion noise reduction technique
    National Institute of Biomedical Imaging and Bioengineering · 2020–2021 · via Hura Imaging, Inc.
    HII 210312-01
  • Co-I
    Development of a Clinically Integrated Prognostic Tool for Alzheimer’s Disease Using Deep Machine Learning Operating on a Connectome Network Diffusion Model
    Foundation of the American Society of Neuroradiology · 2017–2020
    ASNR 184394-01
  • KP
    ADNI-DOD: Effects of Traumatic Brain Injury and Posttraumatic Stress Disorder On Alzheimer's Disease in Veterans Using ADNI
    U.S. Department of Defense · 2015–2019 · via University of Southern California
    WEI1808-1915
  • KP
    Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans Using ADNI
    U.S. Department of Defense · 2015–2018 · via University of Southern California
    WEI1872-06
  • KP
    ADNI2 - Alzheimer's Disease Neuroimaging Initiative
    National Institute on Aging · 2013–2015 · via University of California, San Diego
    U01AG024904-06

Clinical research

5 studies

Active

4 studies
  • PI
    The Effects of Iron on Oxidative Stress and Alzheimer's Disease Biomarkers in Amyloid-Positive and Negative Elderly
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
  • PI
    Quantitative MRI-based cerebral oxygen metabolism in Alzheimer's disease
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)
  • PI
    Brain Health Imaging Institute Bio-Repository
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2024)
  • PI
    The Brain Health Imaging Institute Data Repository
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2020)
Completed & closed trials (1)
  • PI
    Understanding Liver Conditions in Brain Health - BRANYplus Transfer
    Weill Medical College of Cornell University · CLOSED TO ACCRUAL (as of 2025)

Available technologies

News mentions

  • Grant to Develop Portable PET Scanner for Alzheimer’s Disease
    November 4, 2024

    Weill Cornell Medicine researchers have received a $6.2 million, five-year grant from the National Institute on Aging, part of the National Institutes of Health, to build a portable, high-resolution Positron Emission Tomography (PET) scanner that can detect the earliest stages of Alzheimer’s disease.

External relationships

Advisory/Scientific Board Member

Hyperfine Operations, Inc.

Other

Alnylam Pharmaceuticals, Inc. · Efficient CME · Life Molecular Imaging Ltd. · Medical Learning Institute PeerView · Minoryx Therapeutics SL · RTI International