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Highlights

  1. 1
    Nature communications · 2021
    PMID: 33420062PMCID: PMC7794580DOISenior author85 citations
  2. 2
    The Journal of clinical investigation · 2020
    PMID: 32027622PMCID: PMC7191002DOISenior author104 citations
  3. 3
    JCI insight · 2021
    PMID: 33400687PMCID: PMC7934865DOISenior author58 citations

Publications

154 publications

Active

23 grants
  • PI
    Impact of HIV-1 5' Leader Defects on plasma viremia, proviral dynamics, and immune responses
    NIAID · 2026–2031 · via NIH RePORTER
    R01AI198052-01
  • KP
    Columbia University-Weill Cornell Medicine CFAR (CU-WCM CFAR)
    National Institute of Allergy and Infectious Diseases · 2026–2031 · via Columbia University
    P30AI191337-01A1
  • PI
    Biomechanical and Epigenetic Determinants of CTL Resistance in HIV Reservoirs
    National Institute of Allergy and Infectious Diseases · 2026–2031
    R01AI195048-01A1
  • Co-I
    Viral Genetic Determinants of HIV Transcription Control in the Context of HIV Cure
    National Institute of Allergy and Infectious Diseases · 2026–2030
    R01AI203543-01
  • Sub-PI
    Optimizing engineered T cells with highly sensitive anti-HIV/Env HLA-independent T cell receptors (HITs)
    National Institute of Allergy and Infectious Diseases · 2026–2030 · via The Regents of the University of California, San Francisco
    R01AI198049-01A1
  • MPI
    INSPIRE: Innovative Strategies for Personalized Immunotherapies and Reservoir Eradication
    National Institute of Allergy and Infectious Diseases · 2025–2030
    UM1AI191237-02
  • Co-I
    Characterization of Allogeneic T cells mediating HIV cure
    National Institute of Allergy and Infectious Diseases · 2025–2030 · via Oregon Health & Science University
    R01AI189285-01A1
  • KP
    Synergizing Therapeutic Vaccination and EZH2 Inhibition to Enhance CD8 T Cell-Mediated HIV Reservoir Clearance.
    National Institute of Allergy and Infectious Diseases · 2026–2029Fellowship
    F31AI203603-01
  • Sub-PI
    Early interventions at ART initiation to reduce the HIV-1 reservoir and enhance adaptive immune responses
    National Institute of Allergy and Infectious Diseases · 2024–2029 · via University of Pennsylvania
    R01AI184285-02
  • Sub-PI
    The HIV Atlas Study
    amfAR · 2026–2029 · via The Regents of the University of California, San Francisco
    UCSF 260831-01
  • PI
    Defining and then Maximizing the Footprint of CTL Selection on HIV Integration Site Landscapes to Optimize Cure Strategies
    National Institute of Allergy and Infectious Diseases · 2024–2028
    R37AI181626-03
  • KP
    Identification and targeting of metabolic profiles in cytotoxic T-lymphocyte (CTL)-resistant, HIV-infected CD4+ T-cells
    National Institute of Allergy and Infectious Diseases · 2025–2028Fellowship
    F31AI191953-01
  • Sub-PI
    Enterprise for Research and advocacy to Stop and Eradicate HiV (ERASE-HIV)
    National Institute of Allergy and Infectious Diseases · 2021–2028 · via Emory University· 2 renewals
    UM1AI164562-06
  • PI
    Enhancing Susceptibility of HIV Reservoirs to CTL Through a Discovery to Translational Approach
    National Institute of Allergy and Infectious Diseases · 2023–2028
    R01AI176601-04
  • Sub-PI
    Optimizing highly sensitive anti-HIV T cells for in vivo cell engineering
    amfAR · 2025–2027 · via University of California, San Francisco
    UCSF 253800-01
  • PI
    Mechanisms of CTL Resistance in HIV Reservoirs
    National Institute of Allergy and Infectious Diseases · 2022–2027
    R01AI170245-04
  • MPI
    REACH: Research Enterprise to Advance a Cure for HIV
    National Institute of Allergy and Infectious Diseases · 2021–2027· 2 renewals
    UM1AI164565-06
  • Co-I
    Impact of IL-15 immunotherapy on tissue-specific CD8 T cells to reduce the CNS HIV reservoir seeding and persistence
    National Institute of Mental Health · 2023–2027 · via Henry M. Jackson Foundation for the Advancement of Military Medicine
    R01MH130197-02
  • KP
    Cardiovascular Risk of Antiretroviral Therapy Drugs in HIV
    National Heart, Lung, and Blood Institute · 2023–2027 · via Oklahoma Medical Research Foundation
    R01HL167656-01A1
  • Sub-PI
    Targeting HIV-specific T cell differentiation programs to enhance post-treatment control of HIV
    National Institute of Allergy and Infectious Diseases · 2024–2026 · via The Regents of the University of California, San Francisco
    R01AI170239-04
  • Sub-PI
    Measurement of HIV Proviral Reservoir Using Intact Proviral DNA Assay
    Blood & Marrow Transplant Clinical Trials Network · 2020–2026 · via National Marrow Donor ProgramContract
    SA 210262-01
  • Sub-PI
    Understanding Immune Evasion by HIV-1 Repliclones
    National Institute of Allergy and Infectious Diseases · 2021–2026 · via University of Pittsburgh
    R01AI165031-05
  • MPI
    Immunologic control of HIV-1 through combination bNAbs and biologics
    National Institute of Allergy and Infectious Diseases · 2019–2025 · via Rockefeller University
    U01AI145921-05
Completed grants (22)
  • Sub-PI
    Deciphering Mechanisms of HIV Latency Reversal in Perinatal Infection
    National Institute of Allergy and Infectious Diseases · 2020–2024 · via The Johns Hopkins University
    5 R01 AI50412-04
  • PI
    A participant-derived xenograft mouse model to study T-cell-mediated viral control and mRNA vaccine strategies
    National Institute of Allergy and Infectious Diseases · 2022–2024
    R21AI170246-02
  • PI
    Targeted delivery of cytopathicity enhancing agents, and co-ordination with shock and kill, to reduce HIV reservoirs
    National Institute of Allergy and Infectious Diseases · 2019–2024
    R01AI147845-05
  • Sub-PI
    Biomaterials-Enhanced NK Cells for Improved Elimination of the HIV Reservoir
    National Institute of Allergy and Infectious Diseases · 2020–2023 · via George Washington University, The
    R33AI136102-05
  • PI
    Engineered CTL with Inducible Ab Secretion; a Tripartite attack on HIV Reservoirs
    National Institute of Allergy and Infectious Diseases · 2018–2023
    R33AI122391-05
  • PI
    Characterization of a Memory CD4+ T-cell Humanized Mouse Model for the Evaluation of Autologous Cell Therapies and Studies of HIV Persistence
    National Institute of Allergy and Infectious Diseases · 2020–2023
    R21AI152828-02
  • PI
    CTL-Mediated Elimination of Replication Competent vs. Defective HIV Proviruses from Natural Latent Reservoirs: Roles of Antigen Specificity and Functional Characteristics
    National Institute of Allergy and Infectious Diseases · 2018–2023
    R01AI131798-02
  • Co-I
    BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral Eradication
    National Institute of Allergy and Infectious Diseases · 2018–2023
    UM1AI126617-03
  • Sub-PI
    Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure
    National Institute of Allergy and Infectious Diseases · 2018–2023 · via University of Pittsburgh
    U01AI131285-05
  • PI
    Defining & Characterizing Novel Mechanisms by which HIV-infected Primary CD4+ T-cells Intrinsically Resist Elimination by CTL
    National Institute of Allergy and Infectious Diseases · 2020–2022
    R56AI152764-01A1
  • Sub-PI
    Targeting STAT SUMOylation for HIV cure strategies
    National Institute of Allergy and Infectious Diseases · 2020–2022 · via George Washington University, The
    R56AI145683-01A1
  • Co-I
    HIV induced anti-cancer HERV immunity in prostate, breast and colon cancers
    National Cancer Institute · 2018–2022
    R01CA206488-03
  • PI
    Integrating Transcriptomic and Proviral Integration Site Data-Sets to Define Mechanisms of 'CTL Resistance' in Reservoir
    American Foundation for AIDS Research (amfAR) · 2020–2021
    110031-67-RGRL
  • Co-I
    Elimination of HIV using HERV specific T cells
    National Institute of Allergy and Infectious Diseases · 2018–2020
    R01AI076059-11
  • Sub-PI
    Uncovering the Mechanisms of Immune Evasion by HIV-Infected Cell Clones (UM1AI126603 Supplement Proposal; Prime PI is Dan Barouch at BIDMC)
    National Institute of Allergy and Infectious Diseases · 2019–2020 · via Beth Israel Deaconess Medical Center, Inc.
    UM1AI126603-04
  • Sub-PI
    Biomaterials-Enhanced NK Cells for Improved Elimination of the HIV Reservoir
    National Institute of Allergy and Infectious Diseases · 2018–2019 · via George Washington University, The
    R21AI136102-02
  • Sub-PI
    T-cell-mediated targeting of therapeutics to HIV reservoirs.
    National Institute of Allergy and Infectious Diseases · 2018–2019 · via Massachusetts Institute of Technology
    R01AI111860-05
  • MPI
    Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG) [UM1AI068636]
    National Institute of Allergy and Infectious Diseases · 2018–2019 · via University of California, Los Angeles
    UM1AI068636-13
  • PI
    HLA-E-specific TCR-Like Antibodies for the Universal Targeting of Persistent HIV Reservoirs
    American Foundation for AIDS Research (amfAR) · 2018–2019
    109870-62-RGRL
  • PI
    Assessing the CNS as a source of HIV rebound, and evaluating strategies for immune-mediated reservoir elimination
    NIMH · 2016–2019 · via NIH RePORTER
    R21MH112224-02
  • PI
    Engineered CTL with Inducible Ab Secretion; a Tripartite attack on HIV Reservoirs
    NIAID · 2016–2018 · via NIH RePORTER
    R21AI122391-02
  • PI
    Acquisition of the BioRad QX200 AutoDG Droplet Digital PCR System
    OD · 2016–2017 · via NIH RePORTER
    S10OD021622-01

Available technologies

News mentions

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Media highlights

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8 PhD students · 3 Postdocs

PhD · 8

Postdoc · 3

External relationships

Other

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