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Scholars @ Weill Cornell Medicine

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Scholars8,803 Publications201,993 Funding7,268 Clinical research21

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Browse

Scholars8,803 Publications201,993 Funding7,268 Clinical research21

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Status

Completed21
Recruiting14
Enrolling by invitation2
Active, not recruiting8
Terminated9

Study type

Interventional21

Phase

Phase 421
Not reported537
Phase 299
Phase 389
Not applicable87
Phase 129

Investigator

Shari Lipner4
Matthew William McCarthy2
Parag Goyal2
Alexander Drelick1
Catherine Butkus Small1

Show all 19

Department

Medicine13
Dermatology5
Neurology1
Obstetrics and Gynecology1
Pathology and Laboratory Medicine1

Condition

HIV Infections4
Nail Diseases4
Heart Failure3
COVID-192
Heart Diseases2

Show all 21Show fewer

Intervention type

Drug15
Biological5
Device2
Other1

Sponsor type

WCM (investigator-initiated)9
Other academic8
Industry2
Cooperative group1
NIH1

Start date

Has results posted16

Completed×Phase 4×Clear all

Showing 1–20 of 21 studiesSort:

CompletedInterventional · Phase 4NCT02299414 ↗
A Pragmatic Multicenter Randomized Clinical Trial (RCT) of Antihypertensive Therapy for Mild Chronic Hypertension During Pregnancy: Chronic Hypertension and Pregnancy (CHAP) Project

FiltersClear all

Status

Completed21
Recruiting14
Enrolling by invitation2
Active, not recruiting8
Terminated9

Study type

Interventional21

Phase

Phase 421
Not reported537
Phase 299
Phase 389
Not applicable87
Phase 129

Investigator

Shari Lipner4
Matthew William McCarthy2
Parag Goyal2
Alexander Drelick1
Catherine Butkus Small1

Show all 19

Department

Medicine13
Dermatology5
Neurology1
Obstetrics and Gynecology1
Pathology and Laboratory Medicine1

Condition

HIV Infections4
Nail Diseases4
Heart Failure3
COVID-192
Heart Diseases2

Show all 21Show fewer

Intervention type

Drug15
Biological5
Device2
Other1

Sponsor type

WCM (investigator-initiated)9
Other academic8
Industry2
Cooperative group1
NIH1

Start date

Has results posted16

Completed×Phase 4×Clear all

Showing 1–20 of 21 studiesSort:

CompletedInterventional · Phase 4NCT02299414 ↗
A Pragmatic Multicenter Randomized Clinical Trial (RCT) of Antihypertensive Therapy for Mild Chronic Hypertension During Pregnancy: Chronic Hypertension and Pregnancy (CHAP) Project

Phase 1/2

Phase 2/38

Early phase 11

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Dana Jeremy Lukin1
Daniel W Skupski1
Jean W. Pape1
Kira Minkis1
Lisa M Kern1
Marshall J. Glesby1
Marianne Elizabeth Nellis1
Melissa Cushing1
Maria Karas1
Phyllis August1
Joan Stilling1
Roy M Gulick1
Robert S. Brown1
Ulrike W. Kaunzner1

Show all 7

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Pediatrics1
Rehabilitation Medicine1

Hemorrhage2
Afibrinogenemia1
Agnosia1
Amyloid Neuropathies, Familial1
Colitis, Ulcerative1
HIV Seropositivity1
Heart Failure, Diastolic1
Hepatitis C1
Hypertension1
Multiple Sclerosis1
Nails, Malformed1
Recurrence1
Renal Insufficiency1
Renal Insufficiency, Chronic1
Thromboembolism1
Thrombosis1

Phyllis August

Daniel W SkupskiPI

Intervention: Drug: Anti-hypertensive therapy · Other: No anti-hypertensive therapy (unless BP is severe)
Dates: Jun 2015 – Apr 2022· Results posted
Sponsor: University of Alabama

Hypertension

CompletedInterventional · Phase 4NCT02519777 ↗

A Randomized, Double-Blinded, Placebo-Controlled Trial Comparing Antiretroviral Intensification With Maraviroc and Dolutegravir With No Intensification or Intensification With Dolutegravir Alone for the Treatment of Cognitive Impairment in HIV

Marshall J. GlesbyPI

Intervention: Drug: Placebo for maraviroc (MVC) · Drug: Placebo for dolutegravir (DTG) · Drug: Dolutegravir (DTG) · Drug: Maraviroc (MVC)
Dates: Apr 2016 – Dec 2019· Results posted
Sponsor: National Institute of Allergy & Infectious Diseases

HIV Infections

CompletedInterventional · Phase 4NCT03781726 ↗

A Multi-Center, Open-Label Study of Glecaprevir/Pibrentasvir to Treat Recipients of Transplanted Kidneys From Deceased Donors With Hepatitis C Virus

Robert S. BrownPI

Intervention: Drug: glecaprevir/pibrentasvir treatment
Dates: Apr 2019 – Mar 2020· Results posted
Sponsor: The General Hospital Corporation (dba Massachusetts General Hospital)

Renal Failure ChronicHepatitis C

CompletedInterventional · Phase 4NCT03991936 ↗

Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis

Shari LipnerPI

Intervention: Drug: Placebos · Drug: Triamcinolone Acetonide 2.5 mg/mL · Drug: Triamcinolone Acetonide 5.0 mg/mL · Drug: Triamcinolone Acetonide 7.5 mg/mL · Drug: Triamcinolone Acetonide 10 mg/mL
Dates: Mar 2020 – Mar 2023· Results posted
Sponsor: Weill Medical College of Cornell University

Nail PsoriasisNail Diseases

CompletedInterventional · Phase 4NCT04259138 ↗

VERDICT: In actiVE Ulcerative Colitis, a RanDomIzed Controlled Trial for Determination of the Optimal Treatment Target

Dana Jeremy LukinPI

Intervention: Biological: Treatment Algorithm A · Biological: Treatment Algorithm B · Biological: Treatment Algorithm C
Dates: Feb 2020 – Apr 2026
Sponsor: Alimentiv Inc.

Colitis, Ulcerative

CompletedInterventional · Phase 4NCT04265950 ↗

Multicenter, Randomized, Open-Label Trial in Children and Adolescents to Establish Optimal Number of Doses for HPV Vaccination in Children and Adolescents Living With HIV

Jean W. PapePI

Intervention: Biological: Recombinant Human Papillomavirus Nonavalent Vaccine
Dates: Mar 2022 – May 2026
Sponsor: Fred Hutchinson Cancer Center

HIV Infection

CompletedInterventional · Phase 4NCT04363697 ↗

A Multicenter, Randomized, Double-Blind, Parallel Group, Placebo-Controlled Trial to Evaluate the Effect of In-Hospital Initiation of Dapagliflozin on Clinical Outcomes in Patients Who Have Been Stabilized During Hospitalization for Acute Heart Failure DAPAgliflozin and Effect on Cardiovascular Events in ACuTe Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

Maria KarasPI

Intervention: Drug: Dapagliflozin · Drug: Placebo
Dates: Sep 2020 – Jun 2025· Results posted
Sponsor: Brigham and Women's Hospital

Acute Heart FailureHeart Failure

CompletedInterventional · Phase 4NCT04377555 ↗

An Open-Label, Prospective, Single-arm, Multi-center Study to Assess Disease Activity and Biomarkers of Neuronal Damage in Minority Patients With Relapsing Multiple Sclerosis Receiving Treatment With Ocrelizumab

Ulrike W. KaunznerPI

Intervention: Drug: Ocrelizumab
Dates: Jul 2020 – Dec 2022
Sponsor: Genentech, Inc.

Multiple Sclerosis, Relapsing

CompletedInterventional · Phase 4NCT04422795 ↗

The Evaluation of External Thermomechanical Stimulation for Pain Reduction in Patients Undergoing Nail Injection

Shari LipnerPI

Intervention: Device: External thermomechanical device delivering cold and vibration stimuli · Device: External thermomechanical device without delivering cold and vibration stimuli · Drug: Ethyl chloride skin refrigerant spray
Dates: Feb 2024 – Feb 2025 (est.)
Sponsor: Weill Medical College of Cornell University

Nail Diseases

CompletedInterventional · Phase 4NCT04505774 ↗

A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic and Additional Strategies in Hospitalized Adults With COVID-19

Matthew William McCarthyPI

Intervention: Drug: theraputic heparin · Drug: prophylactic heparin · Drug: P2Y12 · Drug: Crizanlizumab Injection · Drug: SGLT2 inhibitor
Dates: Sep 2020 – Aug 2023· Results posted
Sponsor: University of Pittsburgh

Covid19

CompletedInterventional · Phase 4NCT04530630 ↗

The Efficacy, Safety, and Tolerability of Switching to a Bictegravir (BIC)/Emtricitabine(FTC)/Tenofovir Alafenamide (TAF) Regimen in Virally Suppressed Human Immunodeficiency Viruses (HIV)-Positive Patients Post-Renal Transplant

Catherine Butkus SmallPI

Intervention: Drug: BIC/F/TAF 50Mg-200Mg-25Mg Tablet
Dates: Nov 2020 – Aug 2024· Results posted
Sponsor: Weill Medical College of Cornell University

HIV InfectionsRenal Transplant Rejection

CompletedInterventional · Phase 4NCT04636437 ↗

Doravirine for Obese Persons on Integrase Inhibitors and Tenofovir Alafenamide (The Do IT Study)

Roy M GulickPI

Intervention: Drug: Doravirine 100 Mg · Drug: Integrase strand transfer inhibitors · Drug: Tenofovir alafenamide/emtricitabine · Drug: tenofovir disproxil fumarate/emtricitabine
Dates: Jul 2021 – Oct 2024· Results posted
Sponsor: National Institute of Allergy & Infectious Diseases

HIV Infections

CompletedInterventional · Phase 4NCT04757584 ↗

N-of-1 Trials for Deprescribing Beta-blockers in HFpEF

Parag GoyalPI

Intervention: Drug: Beta blockers
Dates: Apr 2021 – Apr 2023· Results posted
Sponsor: Weill Medical College of Cornell University

Heart FailureHeart Failure, DiastolicHeart Failure With Preserved Ejection Fraction+2 more

CompletedInterventional · Phase 4NCT04936542 ↗

A Multicentre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport®) in Comparison With OnabotulinumtoxinA (Botox®) When Treating Adults With Upper Limb Spasticity

Joan StillingPI

Intervention: Biological: AboBoNT-A · Biological: OnaBoNT-A
Dates: Jun 2021 – Aug 2025· Results posted
Sponsor: Ipsen Pharma S.A.S.

Upper Limb Spasticity

CompletedInterventional · Phase 4NCT04941807 ↗

Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome

Shari LipnerPI

Intervention: Device: Platelet-rich plasma · Device: Platelet-poor plasma
Dates: Mar 2021 – Apr 2023· Results posted
Sponsor: Weill Medical College of Cornell University

Nail Diseases

CompletedInterventional · Phase 4NCT05019027 ↗

N-of-1 Trials to Promote Deprescribing in Older Adults With Transthyretin Cardiac Amyloidosis

Parag GoyalPI

Intervention: Drug: Beta blocker
Dates: Jan 2024 – Jun 2026
Sponsor: Weill Medical College of Cornell University

Cardiac AmyloidosisHeart DiseasesTTR Cardiac Amyloidosis

CompletedInterventional · Phase 4NCT05544734 ↗

Analysis of Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

Shari LipnerPI

Intervention: Drug: Hydrocodone 5Mg/Acetaminophen 325Mg Tab · Drug: Acetaminophen 1000mg · Drug: Ibuprofen 400 mg
Dates: Nov 2022 – May 2023· Results posted
Sponsor: Weill Medical College of Cornell University

Nail DiseasesNail Abnormality

CompletedInterventional · Phase 4NCT05711524 ↗

Pilot Clinical Trial of Transfusion of Pathogen Reduced Cryoprecipitated Fibrinogen (INTERCEPT Fibrinogen Complex) in Patients With Bleeding to Expedite Product Availability and Improve Outcomes in Perioperative Bleeding

Melissa CushingPI

Intervention: Biological: Traditional Cryoprecipitate · Biological: Pathogen-Reduced Cryoprecipitate
Dates: Apr 2023 – Oct 2024· Results posted
Sponsor: Weill Medical College of Cornell University

HypofibrinogenemiaBleeding

CompletedInterventional · Phase 4NCT05767749 ↗

Characterizing and Comparing the Duration of Local Anesthetic in Dermatologic Surgery

Kira MinkisPILisa M KernPI

Intervention: Drug: lidocaine + epinephrine 1:100,000 · Drug: Ropivacaine 0.5% Injectable Solution · Drug: Bupivacaine 0.5% Injectable Solution
Dates: Mar 2023 – Jul 2023· Results posted
Sponsor: Weill Medical College of Cornell University

Anesthetics, Local

CompletedInterventional · Phase 4NCT05796557 ↗

ECMO Hemostatic Transfusions in Children

Marianne Elizabeth NellisPI

Intervention: Biological: Platelet Transfusion
Dates: Dec 2023 – Jan 2025· Results posted
Sponsor: Yale University

Extracorporeal Membrane Oxygenation ComplicationHemorrhageThromboembolism+1 more

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