TerminatedInterventional · Phase 3NCT02901626 ↗A Randomized Trial of Pessary in Singleton Pregnancies With a Short CervixDaniel W Skupski
TerminatedInterventional · Not applicableNCT03618095 ↗REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk SubjectsGeoffrey W BergmanPIInterventionDevice: LOTUS Edge Valve SystemDatesJan 2019 – Mar 2021· Results postedSponsorBoston Scientific CorporationAortic Valve Stenosis
TerminatedInterventional · Phase 2/3NCT03693105 ↗A Multi-Site, Randomized, Double-Blind Trial Assessing The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal CognitionConor ListonPIInterventionDevice: Active SAINT Stimulation · Device: Sham SAINT StimulationDatesJun 2024 – Mar 2025SponsorMagnus Medical, Inc.Major Depressive DisorderMajor Depressive EpisodeSuicidal Ideation
TerminatedInterventional · Not applicableNCT03820947 ↗Global, Post-Market, Prospective, Multi-Center, Randomized Controlled Trial of the VenaSeal™ Closure System vs. Surgical Stripping or Endothermal Ablation (ETA) for the Treatment of Early & Advanced Stage Superficial Venous DiseaseNeil M KhilnaniPIInterventionDevice: VenaSeal™ System · Device: Endothermal Ablation (ETA) · Procedure: Surgical StrippingDatesFeb 2020 – Jun 2024· Results postedSponsorMedtronic Vascular, Inc.Venous Reflux
TerminatedInterventional · Phase 3NCT04142658 ↗A Prospective, Randomized, Active (Warfarin) Controlled, Parallel-arm Clinical Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely and Effectively on ApixabanChristopher LauPIInterventionDrug: Apixaban 5 MG · Drug: Apixaban 2.5 MG · Drug: Warfarin · Device: On-X Aortic Mechanical ValveDatesMay 2020 – Dec 2022· Results postedSponsorCryoLife, Inc.Aortic Valve DiseaseAortic Valve StenosisAortic Valve Failure
TerminatedObservationalNCT04431544 ↗AcQMap® US Registry of Procedural and Long-term Clinical Outcomes (Discover-US)Steven M MarkowitzPIInterventionDevice: AcQMap SystemDatesSep 2020 – Nov 2023SponsorAcutus Medical Inc.Ablation of Arrhythmia's
TerminatedInterventional · Phase 2NCT04816604 ↗An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)Irina SobolPIInterventionDrug: GB002 (seralutinib) · Device: Generic Dry Powder InhalerDatesApr 2021 – Sep 2026SponsorGossamer BioPulmonary Arterial Hypertension
TerminatedObservationalNCT04870281 ↗BIO-AffectDX Clinical StudyGeorge ThomasPIInterventionDevice: CRT-DXDatesMay 2021 – Dec 2021SponsorBIOTRONIK GmbH & Co.Heart FailureAtrial FibrillationCardiac Resynchronization Therapy
TerminatedInterventional · Not applicableNCT04964297 ↗Evaluation of Ability to Detect Bowel Gas During Laparoscopic Right Colectomy With Intracorporeal AnastomosisMehraneh Dorna JafariPIInterventionDevice: Obtaining bowel gas samplesDatesAug 2021 – Apr 2024· Results postedSponsorWeill Medical College of Cornell UniversityCrohn's Disease of Large IntestineMalignant Neoplasm of Colon
TerminatedInterventional · Not applicableNCT06330493 ↗Prospective Multi-Center Randomized Controlled Trial to Evaluate the Safety and Efficacy of AcoArt Litos Paclitaxel Coated Percutaneous Transluminal Angioplasty (PTA) Balloon Versus Non-Coated Standard Balloon Angioplasty for the Treatment of Infrapopliteal Obstructions in Patients With Chronic Limb-Threatening IschemiaChristopher AgrusaPIInterventionDevice: PCB · Device: PTADatesOct 2025 – Aug 2026SponsorAcotec Technologies LimitedChronic Limb-Threatening Ischemia
TerminatedInterventional · Not applicableNCT06466148 ↗JessieHug Feasibility and Usability AssessmentJames M KimPIInterventionDevice: JessieHugDatesApr 2024 – Feb 2026SponsorWeill Medical College of Cornell UniversitySIDS