Not yet recruitingInterventional · Not applicableNCT07501676 ↗Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain ReliefMarc SchiffmanPIInterventionDevice: TUNES (Transmucosal Uterosacral Electrical Stimulation) · Device: Sham TUNES DeviceDatesApr 2026 – Sep 2026 (est.)
Not yet recruitingInterventional · Not applicableNCT07580963 ↗Stent Related Symptoms Defined by Ureteral Stent Symptom Questionnaire in Patients With Image-Informed Ureteral Stent LengthsLuay AlsharaPIInterventionDevice: Variable length ureteral stent · Device: Image-informed length ureteral stentDatesSep 2026 – May 2027 (est.)SponsorWeill Medical College of Cornell UniversityUreteral Stent-Related Symptom
RecruitingInterventional · Not applicableNCT07639606 ↗Mobile Cognitive Behavioral Therapy in Early Stroke RecoveryAbhishek JaywantPIInterventionDevice: Mobile Cognitive Behavioral Therapy AppDatesNov 2026 – Mar 2029 (est.)SponsorWeill Medical College of Cornell UniversityAnxietyStrokeDepression - Major Depressive Disorder
RecruitingInterventional · Not applicableNCT07661966 ↗A Pilot Trial of Bright Light Therapy in Patients Receiving First Line Immune Checkpoint BlockadePaul ChapmanPIInterventionDevice: Bright Light TherapyDatesOct 2026 – Dec 2027 (est.)SponsorWeill Medical College of Cornell UniversityMelanoma (Skin Cancer)NSCLC (Non-small Cell Lung Cancer)
RecruitingInterventional · Phase 4NCT07680140 ↗Biomarker-Guided Antidepressant Selection for Treatment-Resistant DepressionConor ListonPIInterventionDevice: TMS · Drug: KetamineDatesAug 2026 – Sep 2028 (est.)SponsorWeill Medical College of Cornell UniversityDepression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
RecruitingInterventional · Phase 4NCT07680153 ↗Neuromodulation of Mood Switch Circuitry in Bipolar DisorderImmanuel ElbauPIInterventionDevice: MagVenture MagPro TMS system · Device: Sham StimulationDatesAug 2026 – Sep 2031 (est.)SponsorWeill Medical College of Cornell UniversityBipolar Disorder (BD)Bipolar 1 DepressionrTMS+1 more
RecruitingInterventional · Not applicableNCT07710352 ↗Comparison Between Low Pressure (8 mmHg) AirSeal Insufflation vs Standard Pressure (15 mmHg) Pneumoperitoneum on Postoperative Recovery in Minimally Invasive Robotic Surgery: A Randomized Controlled TrialCheguevara AfanehPIInterventionDevice: AirSeal Robotic Solution · Other: Standard-pressure pneumoperitoneum (15 mmHg)DatesJul 2026 – Jan 2027 (est.)SponsorWeill Medical College of Cornell UniversityRobotic SurgeryPneumoperitoneum
CompletedInterventional · Not applicableNCT01816776 ↗A Randomized Trial Evaluating the Safety and Effectiveness of the remedē® System in Patients With Central Sleep ApneaJames E. IpPIInterventionDevice: Treatment Group (transvenous stimulation of the phrenic nerve) · Device: Control Group (Optimal Medical Therapy)DatesMar 2013 – Sep 2016· Results postedSponsorRespicardia, IncSleep Apnea, CentralSleep Disordered BreathingHeart Failure
CompletedInterventional · Not applicableNCT02030418 ↗The LEADLESS II IDE Study (Phase I): Safety and Effectiveness Trial for the Nanostim Leadless PacemakerJames E. IpPIInterventionDevice: Leadless PacemakerDatesFeb 2014 – Jun 2015· Results postedSponsorSt. Jude Medical FoundationBradycardia
CompletedObservationalNCT02379104 ↗ROTEM® Sigma Performance Evaluation - Method Comparison With Predicate Device and Reference IntervalsHugh C HemmingsPIInterventionDevice: ROTEM sigmaDatesOct 2017 – Oct 2018 (est.)SponsorInstrumentation LaboratoryBlood Coagulation Disorders
CompletedInterventional · Phase 3NCT02518594 ↗A Randomized Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short CervixDaniel W SkupskiPIInterventionDrug: Vaginal progesterone · Drug: Placebo · Device: Arabin PessaryDatesNov 2015 – Dec 2024· Results postedSponsorEunice Kennedy Shriver National Institute of Child Health and Human DevelopShort Cervical Length
CompletedInterventional · Not applicableNCT02528500 ↗Early Feasibility Assessment of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Type IV Thoracoabdominal Aortic Aneurysms Involving the Visceral Branch VesselsPeter ConnollyPIInterventionDevice: GORE® EXCLUDER® Thoracoabdominal Branch EndoprosthesisDatesNov 2015 – May 2016· Results postedSponsorW.L. Gore & Associates, Inc.Thoracoabdominal Aortic Aneurysm
TerminatedInterventional · Phase 3NCT02901626 ↗A Randomized Trial of Pessary in Singleton Pregnancies With a Short CervixDaniel W SkupskiPIInterventionDevice: Arabin Cervical PessaryDatesFeb 2017 – Apr 2022· Results postedSponsorEunice Kennedy Shriver National Institute of Child Health and Human DevelopShort CervixPreterm Delivery
CompletedInterventional · Not applicableNCT03192696 ↗INSIGHT: EvaluatIoN of the PantheriS OCT- ImaGing AtHerectomy SysTem For Treatment of In-Stent Restenosis (ISR) Lesions In Lower Extremity ArteriesRajeev DayalPIInterventionDevice: Atherectomy CatheterDatesOct 2017 – Jun 2021SponsorAvinger, Inc.Peripheral Arterial Disease
CompletedInterventional · Not applicableNCT03259763 ↗EUS-guided Gastroenterostomy Versus Enteral Stenting for Palliation of Malignant Gastric Outlet Obstruction: A Randomized Clinical TrialReem Z. SharaihaPIInterventionDevice: Lumen-apposing metal stent · Device: Self-expandable metal stentDatesOct 2020 – Jun 2025· Results postedSponsorThe Johns Hopkins UniversityGastric Outlet Obstruction
CompletedInterventional · Phase 3NCT03377491 ↗Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic AdenocarcinomaHiginia CardenesPIInterventionDevice: NovoTTF-200T · Drug: Gemcitabine · Drug: nab paclitaxelDatesMay 2018 – Oct 2024· Results postedSponsorNovocure, Ltd.Pancreas Adenocarcinoma
CompletedInterventional · Phase 2NCT03603808 ↗A Phase 2 Evaluation of VGX-3100, a Synthetic DNA Immunotherapy Targeting Human Papillomavirus 16 and 18 E6 and E7 Proteins, for Anal High-Grade Squamous Intraepithelial Lesions (HSIL) in HIV-Positive IndividualsGrant EllsworthPIInterventionDevice: Electroporation · Biological: HPV DNA Plasmids Therapeutic Vaccine VGX-3100 · Other: Laboratory Biomarker AnalysisDatesSep 2018 – Dec 2024· Results postedSponsorAIDS Malignancy ConsortiumAnal Intraepithelial NeoplasiaHigh Grade Squamous Intraepithelial NeoplasiaHIV Positivity+2 more
TerminatedInterventional · Not applicableNCT03618095 ↗REPRISE IV: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of LOTUS Edge Valve System in IntermediatE Surgical Risk SubjectsGeoffrey W BergmanPIInterventionDevice: LOTUS Edge Valve SystemDatesJan 2019 – Mar 2021· Results postedSponsorBoston Scientific CorporationAortic Valve Stenosis
TerminatedInterventional · Phase 2/3NCT03693105 ↗A Multi-Site, Randomized, Double-Blind Trial Assessing The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal CognitionConor ListonPIInterventionDevice: Active SAINT Stimulation · Device: Sham SAINT StimulationDatesJun 2024 – Mar 2025SponsorMagnus Medical, Inc.Major Depressive DisorderMajor Depressive EpisodeSuicidal Ideation
CompletedInterventional · Not applicableNCT03775512 ↗Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation (PVI) in Subjects With PAFChristopher F LiuPIInterventionDevice: RF Ablation with QDOT MicroDatesJan 2019 – Feb 2022· Results postedSponsorBiosense Webster, Inc.Paroxysmal Atrial Fibrillation