CompletedInterventional · Phase 2NCT01936831 ↗The Early Bactericidal Activity of High-Dose or Standard-Dose Isoniazid Among Adult Participants With Isoniazid-Resistant or Drug-Sensitive Tuberculosis
CompletedInterventional · Phase 2NCT03819114 ↗An Open-Label, Phase II Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis TherapyMarshall J. GlesbyPIInterventionDrug: Levonorgestrel (LNG)DatesMay 2019 – Nov 2020· Results postedSponsorAIDS Clinical Trial GroupHIV InfectionsTuberculosis
CompletedInterventional · Phase 2NCT05007821 ↗A Phase II, Prospective, Randomized, Multicenter Trial to Evaluate the Efficacy and Safety/Tolerability of Two Linezolid Dosing Strategies in Combination With a Short Course Regimen for the Treatment of Drug-Resistant Pulmonary TuberculosisJean W. PapePIInterventionDrug: Linezolid 600 mg · Drug: Linezolid 1200 mg (QD) · Drug: Linezolid 1200 mg (TIW) · Drug: Bedaquiline 200 mg · Drug: Bedaquiline 100 mg · Drug: Delamanid 300 mg · Drug: Clofazimine 300 mg · Drug: Clofazimine 100 mgDatesSep 2022 – Mar 2025· Results postedSponsorAIDS Clinical Trial GroupTuberculosis, Multidrug-ResistantTuberculosisTuberculosis, Pulmonary
CompletedObservationalNCT05981495 ↗Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis DiseaseNishant PrasadPIInterventionDevice: NanoDetect-TBDatesAug 2023 – Dec 2024 (est.)SponsorNanoPin Technologies, Inc.Tuberculosis, PulmonaryTuberculosis, ExtrapulmonaryTuberculosis Active