Active, not recruitingInterventional · Not applicableNCT04153292 ↗SAPIEN M3 System Transcatheter Mitral Valve Replacement Via Transseptal Access
Active, not recruitingInterventional · Not applicableNCT04375332 ↗A Prospective, Multi-center Trial to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair With the HARPOON™ System (RESTORE)Stephanie L. MickPIInterventionDevice: HARPOON™ Beating Heart Mitral Valve Repair SystemDatesDec 2020 – Dec 2027 (est.)SponsorEdwards Lifesciences Corp.Mitral Regurgitation
Active, not recruitingInterventional · Not applicableNCT05051033 ↗Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)Stephanie L. MickPIInterventionProcedure: Mitral valve repair · Device: Transcatheter edge-to-edge repairDatesFeb 2022 – Jun 2029 (est.)SponsorIcahn School of Medicine at Mount SinaiMitral Valve Regurgitation
Active, not recruitingObservationalNCT05526560 ↗A Prospective, Global Study Designed to Collect Real-world Clinical Outcomes of the MITRIS RESILIA Mitral ValveLeonard N GirardiPIInterventionDevice: MITRIS RESILIA Mitral Valve, Model 11400MDatesJan 2023 – Jan 2028 (est.)SponsorEdwards Lifesciences Corp.Mitral StenosisMitral Valve Insufficiency