RecruitingInterventional · Phase 2NCT05999240 ↗A Target Engagement Study of Pimavanserin for Behavioral Inflexibility With Open Label Trial for Rigid Rigid-compulsive Behavior in Adolescents and Adults With Autism
RecruitingInterventional · Phase 2NCT07091279 ↗Randomized Controlled Trial of Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With AutismKaren TangPIInterventionDrug: Propranolol · Drug: PlaceboDatesJan 2026 – Nov 2028 (est.)SponsorNew York State Pyschiatric InstituteAutism Spectrum DisorderChallenging BehaviourAggression+2 more
TerminatedInterventional · Phase 3NCT03504917 ↗A Phase III, Randomized, Double-Blind, Placebo-Controlled, Efficacy, and Safety Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label ExtensionJeremy Veenstra-VanderWeelePIInterventionDrug: Balovaptan · Drug: PlaceboDatesAug 2018 – Mar 2020· Results postedSponsorResearch Foundation for Mental Hygiene, Inc.Autism Spectrum Disorder
CompletedInterventional · Not applicableNCT04146428 ↗Evaluating BOSCC and ELSA as Outcome Measures in the Context of a JASPER Intervention TrialSo Hyun KimPIInterventionBehavioral: clinician-mediated JASPER · Behavioral: parent-mediated JASPERDatesApr 2021 – May 2025SponsorWeill Medical College of Cornell UniversityAutism Spectrum Disorder
CompletedInterventional · Not applicableNCT04675580 ↗Tele Toy Talk: Telehealth Language InterventionStephen KannePIInterventionBehavioral: Toy TalkDatesDec 2020 – Jul 2022SponsorWeill Medical College of Cornell UniversityAutism Spectrum Disorder
CompletedInterventional · Phase 2NCT05067582 ↗A Randomized, Double-Blind, Chronic Dosing (12-weeks), Two-Period, Placebo-Controlled, Crossover, Multi-Center Study to Assess the Efficacy, Safety, and Tolerability of Two Doses of L1-79 for the Treatment of the Core Deficits in Social-Communication Interaction in Adolescents and Young Adults With Autism Spectrum DisorderKaren TangPIInterventionDrug: L1-79DatesJan 2022 – Jun 2024SponsorYamo PharmaceuticalsAutism Spectrum DisorderAutism
CompletedInterventional · Phase 2NCT05081245 ↗A Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD).Karen TangPIInterventionDrug: ML-004 (IR)/(ER) tablet · Drug: ML-004 PlaceboDatesSep 2022 – Mar 2026SponsorMapLight Therapeutics, IncAutism Spectrum Disorder
CompletedInterventional · Not applicableNCT05288868 ↗The Effect of Simulation-based Training on Confidence and Competence in Obtaining Vitals in a Child With AutismKevin ChingPIInterventionOther: Educational Intervention: online didactic lecture and educational simulation activityDatesJun 2022 – May 2024SponsorWeill Medical College of Cornell UniversityAutism Spectrum Disorder