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John Blenis, PhD
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Co-authored with Jennifer Endress
Co-authored publications
John Blenis, PhD and Jennifer Endress · 4 publications
CSV
Word
Isoleucine and valine promote prostate cancer progression via propionyl-CoA-mediated cholesterol metabolism.
Nature metabolism
· 2026
JB
John Blenis
JE
Jennifer Endress
ZL
Zhongchi Li
WJ
Wenbing Jin
LX
Leyi Xiao
+12 more →
PMID:
42625032
·
PMCID:
PMC13493318
·
DOI
·
Abstract
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Nature communications
· 2022
JB
John Blenis
JE
Jennifer Endress
ZL
Zhongchi Li
VL
Vivien Low
EE
Ethan Earlie
+10 more →
PMID:
36266345
·
PMCID:
PMC9584945
·
DOI
·
72 citations
·
Abstract
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells.
Science advances
· 2022
JB
John Blenis
JE
Jennifer Endress
LH
Long He
SC
Sungyun Cho
ZL
Zhongchi Li
+1 more →
PMID:
35594343
·
PMCID:
PMC9122323
·
DOI
·
34 citations
·
Abstract
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Nature
· 2020
JB
John Blenis
JE
Jennifer Endress
VL
Vivien Low
AR
Adam Rosenzweig
TS
Tanya Schild
+3 more →
PMID:
32814897
·
PMCID:
PMC7785256
·
DOI
·
216 citations
·
Abstract