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Scholars/Giovanni Manfredi, MD, PhD/Co-authored with mentees

Co-authored publications with mentees

Giovanni Manfredi, MD, PhD · 18 publications across 4 mentees

PhD mentee

Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
bioRxiv : the preprint server for biology · 2024
GMGiovanni ManfrediNMNicole M SaylesGLGuohua LvCDChiara D Mancinelli+2 more →DEDavid Eliezer
PMID: 39091724PMCID: PMC11291021DOI
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
EMBO molecular medicine · 2024
GMGiovanni ManfrediNMNicole M SaylesNSNneka SouthwellOMOnorina Manzo MDMarilena D'Aurelio+1 more →
PMID: 38724625PMCID: PMC11178915DOI8 citations
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
EMBO molecular medicine · 2024
GMGiovanni ManfrediNSNneka SouthwellOMOnorina ManzoNMNicole M SaylesMDMarilena D'Aurelio+1 more →
PMID: 38724625PMCID: PMC11178915DOI8 citations
With Nneka Southwell · Neuroscience (PhD) · Class of 2025
Correction: Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
Disease models & mechanisms · 2024
GMGiovanni ManfrediNMNicole M SaylesJAJosef Anrather
PMID: 38214340PMCID: PMC10846503DOI
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
Disease models & mechanisms · 2023
GMGiovanni ManfrediNMNicole M SaylesJAJosef Anrather
PMID: 37691621PMCID: PMC10581388DOI8 citations
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
EMBO molecular medicine · 2023
GMGiovanni ManfrediNSNneka SouthwellSSSteven S GrossQCQiuying Chen MDMarilena D'Aurelio
PMID: 37222423PMCID: PMC10331581DOI8 citations
With Nneka Southwell · Neuroscience (PhD) · Class of 2025
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
bioRxiv : the preprint server for biology · 2023
GMGiovanni ManfrediNMNicole M SaylesNSNneka SouthwellOMOnorina Manzo MDMarilena D'Aurelio+1 more →
PMID: 36865125PMCID: PMC9980108DOI
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
bioRxiv : the preprint server for biology · 2023
GMGiovanni ManfrediNSNneka SouthwellOMOnorina ManzoNMNicole M SaylesMDMarilena D'Aurelio+1 more →
PMID: 36865125PMCID: PMC9980108DOI
With Nneka Southwell · Neuroscience (PhD) · Class of 2025
Effects of PB-TURSO on the transcriptional and metabolic landscape of sporadic ALS fibroblasts.
Annals of clinical and translational neurology · 2022
GMGiovanni ManfrediJAJasmine A Fels
PMID: 36083004PMCID: PMC9539390DOI26 citations
With Jasmine Fels · Neuroscience (PhD) · Class of 2022
Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.
Human molecular genetics · 2022
GMGiovanni ManfrediJAJasmine A FelsCKCsaba Konrad
PMID: 35652455PMCID: PMC9558834DOI12 citations
With Jasmine Fels · Neuroscience (PhD) · Class of 2022
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
Cell reports · 2022
GMGiovanni ManfrediNMNicole M SaylesNSNneka SouthwellKMKevin McAvoy SCSuzanne Cloonan
PMID: 35263592PMCID: PMC9013208DOI27 citations
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
Cell reports · 2022
GMGiovanni ManfrediNSNneka SouthwellNMNicole M SaylesKMKevin McAvoy SCSuzanne Cloonan
PMID: 35263592PMCID: PMC9013208DOI27 citations
With Nneka Southwell · Neuroscience (PhD) · Class of 2025
Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1^G93A astrocytes.
Autophagy · 2021
GMGiovanni ManfrediNMNicole M SaylesVGVeronica GranatieroCKCsaba KonradMGMichael G Kharas+1 more →
PMID: 33749521PMCID: PMC8726657DOI41 citations
With Nicole Sayles · Neuroscience (PhD) · Class of 2024
Sex and oestrogen receptor β have modest effects on gene expression in the mouse brain posterior cortex.
Endocrinology, diabetes & metabolism · 2020
GMGiovanni ManfrediJAJasmine A Fels
PMID: 33532622PMCID: PMC7831211DOI4 citations
With Jasmine Fels · Neuroscience (PhD) · Class of 2022
ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response.
Acta neuropathologica · 2019
GMGiovanni ManfrediSRSuzanne R BursteinKBKirsten BredvikSMSamantha M MeadowsTATeresa A Milner+1 more →
PMID: 30877432PMCID: PMC6571048DOI91 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017
Sex Differences in Ischemia/Reperfusion Injury: The Role of Mitochondrial Permeability Transition.
Neurochemical research · 2019
GMGiovanni ManfrediJAJasmine A Fels
PMID: 30863968PMCID: PMC6742589DOI43 citations
With Jasmine Fels · Neuroscience (PhD) · Class of 2022
Estrogen receptor beta modulates permeability transition in brain mitochondria.
Biochimica et biophysica acta. Bioenergetics · 2018
GMGiovanni ManfrediSRSuzanne R BursteinJAJasmine A FelsLQLiping Qian PZPing Zhou+2 more →
PMID: 29550215PMCID: PMC5912174DOI44 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017
Estrogen receptor beta modulates permeability transition in brain mitochondria.
Biochimica et biophysica acta. Bioenergetics · 2018
GMGiovanni ManfrediJAJasmine A FelsSRSuzanne R BursteinLQLiping Qian PZPing Zhou+2 more →
PMID: 29550215PMCID: PMC5912174DOI44 citations
With Jasmine Fels · Neuroscience (PhD) · Class of 2022
In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions.
Human molecular genetics · 2018
GMGiovanni ManfrediSRS R BursteinHKHibiki Kawamata Fujita TATeresa A Milner SCSuzanne Cloonan
PMID: 29112723PMCID: PMC5886281DOI90 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017
Distinct intracellular sAC-cAMP domains regulate ER Ca²⁺ signaling and OXPHOS function.
Journal of cell science · 2017
GMGiovanni ManfrediSRSuzanne R BursteinCKCsaba KonradMDMarilena D'Aurelio AGAlexander Galkin+4 more →
PMID: 28864766PMCID: PMC5702058DOI26 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017
Sex specific activation of the ERα axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS.
Human molecular genetics · 2017
GMGiovanni ManfrediSRSuzanne R Burstein
PMID: 28186560PMCID: PMC6075578DOI65 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017
Abnormal intracellular calcium signaling and SNARE-dependent exocytosis contributes to SOD1G93A astrocyte-mediated toxicity in amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
GMGiovanni ManfrediSBSuzanne BursteinHKHibiki Kawamata Fujita
PMID: 24501372PMCID: PMC3913875DOI90 citations
With Suzanne Burstein · Neuroscience (PhD) · Class of 2017