Co-authored publications with mentees

PhD mentee

• Diisonitrile Chalkophore Structure and Function in Mycobacterial Copper Acquisition.

  Journal of the American Chemical Society · 2026

  PMID: 42913580·PMCID: PMC13674278·DOI·Abstract

  With Pooja Pandya · Pharmacology (PhD)

• Structural basis for transthiolation intermediates in the ubiquitin pathway.

  Nature · 2024

  DSDerek S TanAMAvelyn Mae V Delos ReyesCDChristopher D Lima

  PMID: 39143218·PMCID: PMC11374688·DOI·27 citations·Abstract

  With Avelyn Mae Delos Reyes · Pharmacology (PhD) · Class of 2024

• Design and synthesis of a library of C8-substituted sulfamidoadenosines to probe bacterial permeability.

  Bioorganic & medicinal chemistry letters · 2024

  DSDerek S TanMLMelissa L BobyDBDipti Barman

  PMID: 38851357·PMCID: PMC11361631·DOI·Abstract

  With Melissa Boby · Pharmacology (PhD) · Class of 2024

• Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions.

  Organic letters · 2024

  DSDerek S TanAMAvelyn Mae V Delos ReyesCDChristopher D Lima

  PMID: 38781175·PMCID: PMC11165569·DOI·5 citations·Abstract

  With Avelyn Mae Delos Reyes · Pharmacology (PhD) · Class of 2024

• Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis.

  Chemical science · 2023

  DSDerek S TanAMAvelyn Mae V Delos ReyesCNChristopher Nieves

  PMID: 37799988·PMCID: PMC10548506·DOI·15 citations·Abstract

  With Avelyn Mae Delos Reyes · Pharmacology (PhD) · Class of 2024

• Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis.

  Chemical science · 2023

  DSDerek S TanCNChristopher NievesAMAvelyn Mae V Delos Reyes

  PMID: 37799988·PMCID: PMC10548506·DOI·15 citations·Abstract

  With Christopher Nieves · Tri-I Program in Chemical Biology (PhD)

• Design and synthesis of a library of C2-substituted sulfamidoadenosines to probe bacterial permeability.

  Bioorganic & medicinal chemistry letters · 2023

  DSDerek S TanMLMelissa L Boby

  PMID: 37734424·PMCID: PMC10842738·DOI·2 citations·Abstract

  With Melissa Boby · Pharmacology (PhD) · Class of 2024

• Development of a p-Hydroxybenzyl-Alcohol-Linked Glutamate Prodrug for Activation by Pseudomonas Carboxypeptidase G2.

  Organic letters · 2023

  DSDerek S TanBCBroderick C CorlessDADavid A. Scheinberg

  PMID: 37602700·PMCID: PMC10543097·DOI·5 citations·Abstract

  With Broderick Corless · Pharmacology (PhD) · Class of 2023

• Host Interactions with Engineered T-cell Micropharmacies.

  Cancer immunology research · 2023

  DSDerek S TanBCBroderick C CorlessCMChristopher M BournePWPatrick Wallisch+4 more →DADavid A. Scheinberg

  PMID: 37379366·PMCID: PMC10472090·DOI·4 citations·Abstract

  With Broderick Corless · Pharmacology (PhD) · Class of 2023

• Host-cell Interactions of Engineered T cell Micropharmacies.

  bioRxiv : the preprint server for biology · 2023

  DSDerek S TanBCBroderick C CorlessCMChristopher M BournePWPatrick Wallisch+4 more →DADavid A. Scheinberg

  PMID: 37205431·PMCID: PMC10187158·DOI·Abstract

  With Broderick Corless · Pharmacology (PhD) · Class of 2023

• Chemoenzymatic Synthesis of Novel Cytotoxic Epoxyketones Using the Eponemycin Biosynthetic Enzyme EpnF.

  ACS chemical biology · 2023

  DSDerek S TanBCBroderick C CorlessNANicholas A PrescottYDYael DavidDADavid A. Scheinberg

  PMID: 37172287·PMCID: PMC10358350·DOI·6 citations·Abstract

  With Broderick Corless · Pharmacology (PhD) · Class of 2023

• Engineering CAR-T cells to activate small-molecule drugs in situ.

  Nature chemical biology · 2021

  DSDerek S TanBCBroderick C CorlessCMChristopher M BourneKKKeifer Kurtz+2 more →DADavid A. Scheinberg

  PMID: 34969970·PMCID: PMC9152922·DOI·77 citations·Abstract

  With Broderick Corless · Pharmacology (PhD) · Class of 2023

• Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes.

  Methods in enzymology · 2020

  DSDerek S TanLCLisa C Standke

  PMID: 32416922·PMCID: PMC7367610·DOI·2 citations·Abstract

  With Lisa Standke · Pharmacology (PhD) · Class of 2022

• Synthesis of bicyclic ethers by a palladium-catalyzed oxidative cyclization-redox relay-π-allyl-Pd cyclization cascade reaction.

  Chemical communications (Cambridge, England) · 2019

  DSDerek S TanMLMelissa L BobyMCMichaelyn C Lux

  PMID: 31147660·PMCID: PMC6601619·DOI·10 citations·Abstract

  With Melissa Boby · Pharmacology (PhD) · Class of 2024

• Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors.

  The Journal of antibiotics · 2019

  DSDerek S TanLCLisa C StandkeMCMichaelyn C Lux

  PMID: 30982830·PMCID: PMC6594144·DOI·42 citations·Abstract

  With Lisa Standke · Pharmacology (PhD) · Class of 2022

• Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents.

  Biochemistry · 2019

  DSDerek S TanLCLisa C Standke

  PMID: 30582694·PMCID: PMC6530907·DOI·12 citations·Abstract

  With Lisa Standke · Pharmacology (PhD) · Class of 2022

• Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

  ACS central science · 2018

  DSDerek S TanALAlyssa L VeranoDEDavid E Olson

  PMID: 30648156·PMCID: PMC6311695·DOI·36 citations·Abstract

  With Alyssa Verano · Pharmacology (PhD) · Class of 2017

• Stereocontrolled Synthesis of Spiroketals: An Engine for Chemical and Biological Discovery.

  Israel journal of chemistry · 2017

  DSDerek S TanALAlyssa L Verano

  PMID: 29104308·PMCID: PMC5665374·DOI·11 citations·Abstract

  With Alyssa Verano · Pharmacology (PhD) · Class of 2017

• Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants.

  Chemical science · 2017

  DSDerek S TanALAlyssa L Verano

  PMID: 28845229·PMCID: PMC5571482·DOI·16 citations·Abstract

  With Alyssa Verano · Pharmacology (PhD) · Class of 2017

• Stereoselective synthesis of acortatarins A and B.

  Organic letters · 2012

  DSDerek S TanALAlyssa L Verano

  PMID: 22924668·PMCID: PMC3466107·DOI·30 citations·Abstract

  With Alyssa Verano · Pharmacology (PhD) · Class of 2017