Co-authored publications with mentees

Dan Avi Landau, MD, PhD · 33 publications across 14 mentees

CSV Word

MD mentee

Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauPOPatrick O BolanAWAdam WidmanNONathaniel OmansAHAndrew H Lipsky+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Patrick Bolan · MD mentee · Class of 2020
Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.
Cell systems · 2019
DADan Avi LandauPOPatrick O BolanNDNeville Dusaj
PMID: 31668800PMCID: PMC6981068DOI15 citations
With Patrick Bolan · MD mentee · Class of 2020

MD-PhD mentee

Single-cell mapping of regulatory DNA-protein interactions.
Cell · 2026
DADan Avi LandauJPJoe PeltSYSangho Yoon EGEvrim GokselLMLevan Mekerishvili+3 more →
PMID: 42242226PMCID: PMC13366695DOI1 citations
With Joe Pelt · MD-PhD WGS Physiology, Biophysics & System Biology (MD-PhD) · Class of 2024
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauEOElliot O EtonRMRobert M MyersSGSaravanan GanesanLMLevan Mekerishvili+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Elliot Eton · MD-PhD Program (MD-PhD)

PhD mentee

Type 1 interferon perturbates clonal competition by reshaping human blood development.
Nature genetics · 2026
DADan Avi LandauNONathaniel OmansCLChhiring LamaDIDanielle Isakov+14 more →ANAnna Nam
PMID: 42745000DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Single-cell mapping of regulatory DNA-protein interactions.
Cell · 2026
DADan Avi LandauLMLevan MekerishviliSYSangho Yoon EGEvrim GokselJPJoe Pelt+3 more →
PMID: 42242226PMCID: PMC13366695DOI1 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Somatic cancer variants enriched in Alzheimer's disease microglia-like cells drive inflammatory and proliferative states.
Cell · 2026
DADan Avi LandauLMLevan Mekerishvili
PMID: 42019491PMCID: PMC13107304DOI4 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
Cancer discovery · 2026
DADan Avi LandauLMLevan MekerishviliSSShayan Saniei
PMID: 41351880PMCID: PMC12861042DOI1 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Large-scale single-cell phylogenetic mapping of clonal evolution in the human aging esophagus.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauNONathaniel OmansFFFoteini FotopoulouNRNeil RuthenSRSrinivas Rajagopalan+3 more →
PMID: 41279007PMCID: PMC12632828DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Large-scale single-cell phylogenetic mapping of clonal evolution in the human aging esophagus.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanFFFoteini FotopoulouNRNeil RuthenJSJoshua S Schiffman+3 more →
PMID: 41279007PMCID: PMC12632828DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanDJDennis Jinglun Yuan JEJonathan E. ShoagMAMajd Al Assaad+7 more →
PMID: 40832334PMCID: PMC12363824DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.
Nature methods · 2025
DADan Avi LandauSRSrinivas RajagopalanRMRebecca MurrayTLTheophile LanganayHCHoyin Chu+10 more →
PMID: 40217113PMCID: PMC12077166DOI13 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauNONathaniel OmansSRSrinivas RajagopalanJQJean QuentinJLJulien Laval+1 more →
PMID: 40166290PMCID: PMC11957134DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanJQJean QuentinJLJulien LavalNONathaniel Omans+1 more →
PMID: 40166290PMCID: PMC11957134DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauLMLevan MekerishviliSSShayan Saniei
PMID: 40166161PMCID: PMC11957141DOI
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Single-cell mapping of regulatory DNA:Protein interactions.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauLMLevan MekerishviliWCWei-Yu ChiSYSangho Yoon SGSaravanan Ganesan
PMID: 39803441PMCID: PMC11722406DOI
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Single-cell mapping of regulatory DNA:Protein interactions.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauWCWei-Yu ChiSYSangho YoonLMLevan MekerishviliSGSaravanan Ganesan
PMID: 39803441PMCID: PMC11722406DOI
With Wei-Yu Chi · Physiology, Biophysics & Systems Biology (PhD) · Class of 2026
Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap.
Nature biotechnology · 2024
DADan Avi LandauXNXiang NiuJCJacqueline Chou
PMID: 39375448PMCID: PMC12263428DOI41 citations
With Xiang Niu · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2023
Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution.
Nature genetics · 2024
DADan Avi LandauSRSrinivas RajagopalanJSJoshua S SchiffmanARAndrew Raphael D'AvinoTPTamara Prieto
PMID: 39317739PMCID: PMC11527590DOI25 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment.
Nature medicine · 2024
DADan Avi LandauSRSrinivas RajagopalanADAditya DeshpandeJQJean QuentinTLTheophile Langanay+7 more →
PMID: 38877116PMCID: PMC7616143DOI115 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauLMLevan MekerishviliRMRobert M MyersSGSaravanan GanesanTPTamara Prieto+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Integration of whole transcriptome spatial profiling with protein markers.
Nature biotechnology · 2023
DADan Avi LandauXNXiang NiuNBNir Ben Chetrit
PMID: 36593397PMCID: PMC10272089DOI168 citations
With Xiang Niu · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2023
Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution.
Nature biotechnology · 2022
DADan Avi LandauLMLevan Mekerishvili
PMID: 36536150PMCID: PMC10272075DOI64 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauNONathaniel OmansAWAdam WidmanPOPatrick O BolanAHAndrew H Lipsky+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature · 2019
DADan Avi LandauNONathaniel OmansANAnna NamRCRonan ChaligneFIFranco Izzo+7 more →
PMID: 31270458PMCID: PMC6782071DOI263 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauNONathaniel OmansFGFederico GaitiRCRonan ChaligneKGKirill Grigorev+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Deep learning mutation prediction enables early stage lung cancer detection in liquid biopsy
· 2018
Source: Scopus
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)

Postdoc mentee

A single-cell lens into the co-evolution of genotypes and phenotypes in cancer.
Nature reviews. Cancer · 2026
DADan Avi LandauTPTamara PrietoCPCatherine Potenski
PMID: 42711452DOI
With Tamara Prieto · Postdoc mentee
Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation.
Nature genetics · 2026
DADan Avi LandauRCRonan ChaligneJSJoshua S SchiffmanHHHusain Haiderali Danish
PMID: 42332268PMCID: PMC13364636DOI4 citations
With Ronan Chaligne · Postdoc mentee
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.
bioRxiv : the preprint server for biology · 2025
DADan Avi Landau DJDennis Jinglun YuanSRSrinivas RajagopalanJEJonathan E. ShoagMAMajd Al Assaad+7 more →
PMID: 40832334PMCID: PMC12363824DOI
With Dennis Jinglun Yuan · Postdoc mentee
Deconvoluting clonal and cellular architecture in IDH-mutant acute myeloid leukemia.
Cell stem cell · 2025
DADan Avi LandauRCRonan ChaligneRMRobert M MyersKMKamal MenghrajaniMRMikhail Roshal
PMID: 40409258PMCID: PMC12857296DOI23 citations
With Ronan Chaligne · Postdoc mentee
RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax.
Nature · 2024
DADan Avi LandauRCRonan ChalignePLPiro Lito
PMID: 39478230PMCID: PMC11618090DOI79 citations
With Ronan Chaligne · Postdoc mentee
Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution.
Nature genetics · 2024
DADan Avi LandauTPTamara PrietoJSJoshua S SchiffmanARAndrew Raphael D'AvinoSRSrinivas Rajagopalan
PMID: 39317739PMCID: PMC11527590DOI25 citations
With Tamara Prieto · Postdoc mentee
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment.
Nature medicine · 2024
DADan Avi LandauAPAlexandre Pellan ChengSRSrinivas RajagopalanADAditya DeshpandeJQJean Quentin+7 more →
PMID: 38877116PMCID: PMC7616143DOI115 citations
With Alexandre Cheng · Postdoc mentee
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauTPTamara PrietoRMRobert M MyersSGSaravanan GanesanLMLevan Mekerishvili+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Tamara Prieto · Postdoc mentee
A heritable, non-genetic road to cancer evolution.
Nature · 2022
DADan Avi LandauTPTamara Prieto
PMID: 34880486DOI5 citations
With Tamara Prieto · Postdoc mentee
Lightning does strike twice: leveraging phased variants to enhance minimal residual disease detection.
Med (New York, N.Y.) · 2021
DADan Avi LandauAPAlexandre P Cheng
PMID: 35590202DOI2 citations
With Alexandre Cheng · Postdoc mentee
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.
Nature genetics · 2021
DADan Avi LandauFGFederico GaitiAAAlicia AlonsoFIFranco Izzo
PMID: 34594037PMCID: PMC8675181DOI204 citations
With Federico Gaiti · Postdoc mentee
Smart-RRBS for single-cell methylome and transcriptome analysis.
Nature protocols · 2021
DADan Avi LandauFGFederico Gaiti
PMID: 34244697PMCID: PMC8672372DOI60 citations
With Federico Gaiti · Postdoc mentee
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.
Nature reviews. Genetics · 2020
DADan Avi LandauRCRonan ChaligneANAnna Nam
PMID: 32807900PMCID: PMC8450921DOI347 citations
With Ronan Chaligne · Postdoc mentee
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauFGFederico GaitiAWAdam WidmanNONathaniel OmansPOPatrick O Bolan+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Federico Gaiti · Postdoc mentee
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics · 2020
DADan Avi LandauRCRonan ChaligneFIFranco IzzoAPAsaf PoranFGFederico Gaiti+3 more →
PMID: 32203468PMCID: PMC7216752DOI191 citations
With Ronan Chaligne · Postdoc mentee
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics · 2020
DADan Avi LandauFGFederico GaitiFIFranco IzzoAPAsaf PoranRCRonan Chaligne+3 more →
PMID: 32203468PMCID: PMC7216752DOI191 citations
With Federico Gaiti · Postdoc mentee
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature · 2019
DADan Avi LandauRCRonan ChaligneANAnna NamFIFranco IzzoRMRobert M Myers+7 more →
PMID: 31270458PMCID: PMC6782071DOI263 citations
With Ronan Chaligne · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauRCRonan ChaligneFGFederico GaitiKGKirill GrigorevDRDavide Risso+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Ronan Chaligne · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauFGFederico GaitiRCRonan ChaligneKGKirill GrigorevDRDavide Risso+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Federico Gaiti · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauKKKyu-Tae KimFGFederico GaitiRCRonan ChaligneKGKirill Grigorev+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Kyu-Tae Kim · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauRCRonan ChaligneFGFederico GaitiSKScott KulmWBWendy Béguelin+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Ronan Chaligne · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauFGFederico GaitiSKScott KulmRCRonan ChaligneWBWendy Béguelin+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Federico Gaiti · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauKKKyu-Tae KimFGFederico GaitiSKScott KulmRCRonan Chaligne+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Kyu-Tae Kim · Postdoc mentee
TARGET-seq Takes Aim at Cancer Evolution through Multi-omics Single-Cell Genotyping and Transcriptomics.
Molecular cell · 2019
DADan Avi LandauRCRonan ChaligneANAnna Nam
PMID: 30901562DOI6 citations
With Ronan Chaligne · Postdoc mentee

Co-authored publications with mentees

Dan Avi Landau, MD, PhD · 33 publications across 14 mentees

CSV Word

MD mentee

Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauPOPatrick O BolanAWAdam WidmanNONathaniel OmansAHAndrew H Lipsky+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Patrick Bolan · MD mentee · Class of 2020
Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.
Cell systems · 2019
DADan Avi LandauPOPatrick O BolanNDNeville Dusaj
PMID: 31668800PMCID: PMC6981068DOI15 citations
With Patrick Bolan · MD mentee · Class of 2020

MD-PhD mentee

Single-cell mapping of regulatory DNA-protein interactions.
Cell · 2026
DADan Avi LandauJPJoe PeltSYSangho Yoon EGEvrim GokselLMLevan Mekerishvili+3 more →
PMID: 42242226PMCID: PMC13366695DOI1 citations
With Joe Pelt · MD-PhD WGS Physiology, Biophysics & System Biology (MD-PhD) · Class of 2024
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauEOElliot O EtonRMRobert M MyersSGSaravanan GanesanLMLevan Mekerishvili+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Elliot Eton · MD-PhD Program (MD-PhD)

PhD mentee

Type 1 interferon perturbates clonal competition by reshaping human blood development.
Nature genetics · 2026
DADan Avi LandauNONathaniel OmansCLChhiring LamaDIDanielle Isakov+14 more →ANAnna Nam
PMID: 42745000DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Single-cell mapping of regulatory DNA-protein interactions.
Cell · 2026
DADan Avi LandauLMLevan MekerishviliSYSangho Yoon EGEvrim GokselJPJoe Pelt+3 more →
PMID: 42242226PMCID: PMC13366695DOI1 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Somatic cancer variants enriched in Alzheimer's disease microglia-like cells drive inflammatory and proliferative states.
Cell · 2026
DADan Avi LandauLMLevan Mekerishvili
PMID: 42019491PMCID: PMC13107304DOI4 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
Cancer discovery · 2026
DADan Avi LandauLMLevan MekerishviliSSShayan Saniei
PMID: 41351880PMCID: PMC12861042DOI1 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Large-scale single-cell phylogenetic mapping of clonal evolution in the human aging esophagus.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauNONathaniel OmansFFFoteini FotopoulouNRNeil RuthenSRSrinivas Rajagopalan+3 more →
PMID: 41279007PMCID: PMC12632828DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Large-scale single-cell phylogenetic mapping of clonal evolution in the human aging esophagus.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanFFFoteini FotopoulouNRNeil RuthenJSJoshua S Schiffman+3 more →
PMID: 41279007PMCID: PMC12632828DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanDJDennis Jinglun Yuan JEJonathan E. ShoagMAMajd Al Assaad+7 more →
PMID: 40832334PMCID: PMC12363824DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.
Nature methods · 2025
DADan Avi LandauSRSrinivas RajagopalanRMRebecca MurrayTLTheophile LanganayHCHoyin Chu+10 more →
PMID: 40217113PMCID: PMC12077166DOI13 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauNONathaniel OmansSRSrinivas RajagopalanJQJean QuentinJLJulien Laval+1 more →
PMID: 40166290PMCID: PMC11957134DOI
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauSRSrinivas RajagopalanJQJean QuentinJLJulien LavalNONathaniel Omans+1 more →
PMID: 40166290PMCID: PMC11957134DOI
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauLMLevan MekerishviliSSShayan Saniei
PMID: 40166161PMCID: PMC11957141DOI
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Single-cell mapping of regulatory DNA:Protein interactions.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauLMLevan MekerishviliWCWei-Yu ChiSYSangho Yoon SGSaravanan Ganesan
PMID: 39803441PMCID: PMC11722406DOI
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Single-cell mapping of regulatory DNA:Protein interactions.
bioRxiv : the preprint server for biology · 2025
DADan Avi LandauWCWei-Yu ChiSYSangho YoonLMLevan MekerishviliSGSaravanan Ganesan
PMID: 39803441PMCID: PMC11722406DOI
With Wei-Yu Chi · Physiology, Biophysics & Systems Biology (PhD) · Class of 2026
Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap.
Nature biotechnology · 2024
DADan Avi LandauXNXiang NiuJCJacqueline Chou
PMID: 39375448PMCID: PMC12263428DOI41 citations
With Xiang Niu · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2023
Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution.
Nature genetics · 2024
DADan Avi LandauSRSrinivas RajagopalanJSJoshua S SchiffmanARAndrew Raphael D'AvinoTPTamara Prieto
PMID: 39317739PMCID: PMC11527590DOI25 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment.
Nature medicine · 2024
DADan Avi LandauSRSrinivas RajagopalanADAditya DeshpandeJQJean QuentinTLTheophile Langanay+7 more →
PMID: 38877116PMCID: PMC7616143DOI115 citations
With Srinivas Rajagopalan · Physiology, Biophysics & Systems Biology (PhD)
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauLMLevan MekerishviliRMRobert M MyersSGSaravanan GanesanTPTamara Prieto+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Integration of whole transcriptome spatial profiling with protein markers.
Nature biotechnology · 2023
DADan Avi LandauXNXiang NiuNBNir Ben Chetrit
PMID: 36593397PMCID: PMC10272089DOI168 citations
With Xiang Niu · Tri-I Program in Computational Biology & Medicine (PhD) · Class of 2023
Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution.
Nature biotechnology · 2022
DADan Avi LandauLMLevan Mekerishvili
PMID: 36536150PMCID: PMC10272075DOI64 citations
With Levan Mekerishvili · Physiology, Biophysics & Systems Biology (PhD)
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauNONathaniel OmansAWAdam WidmanPOPatrick O BolanAHAndrew H Lipsky+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature · 2019
DADan Avi LandauNONathaniel OmansANAnna NamRCRonan ChaligneFIFranco Izzo+7 more →
PMID: 31270458PMCID: PMC6782071DOI263 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauNONathaniel OmansFGFederico GaitiRCRonan ChaligneKGKirill Grigorev+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)
Deep learning mutation prediction enables early stage lung cancer detection in liquid biopsy
· 2018
Source: Scopus
With Nathaniel Omans · Tri-I Program in Computational Biology & Medicine (PhD)

Postdoc mentee

A single-cell lens into the co-evolution of genotypes and phenotypes in cancer.
Nature reviews. Cancer · 2026
DADan Avi LandauTPTamara PrietoCPCatherine Potenski
PMID: 42711452DOI
With Tamara Prieto · Postdoc mentee
Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation.
Nature genetics · 2026
DADan Avi LandauRCRonan ChaligneJSJoshua S SchiffmanHHHusain Haiderali Danish
PMID: 42332268PMCID: PMC13364636DOI4 citations
With Ronan Chaligne · Postdoc mentee
Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.
bioRxiv : the preprint server for biology · 2025
DADan Avi Landau DJDennis Jinglun YuanSRSrinivas RajagopalanJEJonathan E. ShoagMAMajd Al Assaad+7 more →
PMID: 40832334PMCID: PMC12363824DOI
With Dennis Jinglun Yuan · Postdoc mentee
Deconvoluting clonal and cellular architecture in IDH-mutant acute myeloid leukemia.
Cell stem cell · 2025
DADan Avi LandauRCRonan ChaligneRMRobert M MyersKMKamal MenghrajaniMRMikhail Roshal
PMID: 40409258PMCID: PMC12857296DOI23 citations
With Ronan Chaligne · Postdoc mentee
RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax.
Nature · 2024
DADan Avi LandauRCRonan ChalignePLPiro Lito
PMID: 39478230PMCID: PMC11618090DOI79 citations
With Ronan Chaligne · Postdoc mentee
Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution.
Nature genetics · 2024
DADan Avi LandauTPTamara PrietoJSJoshua S SchiffmanARAndrew Raphael D'AvinoSRSrinivas Rajagopalan
PMID: 39317739PMCID: PMC11527590DOI25 citations
With Tamara Prieto · Postdoc mentee
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment.
Nature medicine · 2024
DADan Avi LandauAPAlexandre Pellan ChengSRSrinivas RajagopalanADAditya DeshpandeJQJean Quentin+7 more →
PMID: 38877116PMCID: PMC7616143DOI115 citations
With Alexandre Cheng · Postdoc mentee
Mapping genotypes to chromatin accessibility profiles in single cells.
Nature · 2024
DADan Avi LandauTPTamara PrietoRMRobert M MyersSGSaravanan GanesanLMLevan Mekerishvili+5 more →
PMID: 38720070PMCID: PMC11139586DOI50 citations
With Tamara Prieto · Postdoc mentee
A heritable, non-genetic road to cancer evolution.
Nature · 2022
DADan Avi LandauTPTamara Prieto
PMID: 34880486DOI5 citations
With Tamara Prieto · Postdoc mentee
Lightning does strike twice: leveraging phased variants to enhance minimal residual disease detection.
Med (New York, N.Y.) · 2021
DADan Avi LandauAPAlexandre P Cheng
PMID: 35590202DOI2 citations
With Alexandre Cheng · Postdoc mentee
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.
Nature genetics · 2021
DADan Avi LandauFGFederico GaitiAAAlicia AlonsoFIFranco Izzo
PMID: 34594037PMCID: PMC8675181DOI204 citations
With Federico Gaiti · Postdoc mentee
Smart-RRBS for single-cell methylome and transcriptome analysis.
Nature protocols · 2021
DADan Avi LandauFGFederico Gaiti
PMID: 34244697PMCID: PMC8672372DOI60 citations
With Federico Gaiti · Postdoc mentee
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.
Nature reviews. Genetics · 2020
DADan Avi LandauRCRonan ChaligneANAnna Nam
PMID: 32807900PMCID: PMC8450921DOI347 citations
With Ronan Chaligne · Postdoc mentee
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring.
Nature medicine · 2020
DADan Avi LandauFGFederico GaitiAWAdam WidmanNONathaniel OmansPOPatrick O Bolan+4 more →
PMID: 32483360PMCID: PMC8108131DOI342 citations
With Federico Gaiti · Postdoc mentee
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics · 2020
DADan Avi LandauRCRonan ChaligneFIFranco IzzoAPAsaf PoranFGFederico Gaiti+3 more →
PMID: 32203468PMCID: PMC7216752DOI191 citations
With Ronan Chaligne · Postdoc mentee
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Nature genetics · 2020
DADan Avi LandauFGFederico GaitiFIFranco IzzoAPAsaf PoranRCRonan Chaligne+3 more →
PMID: 32203468PMCID: PMC7216752DOI191 citations
With Federico Gaiti · Postdoc mentee
Somatic mutations and cell identity linked by Genotyping of Transcriptomes.
Nature · 2019
DADan Avi LandauRCRonan ChaligneANAnna NamFIFranco IzzoRMRobert M Myers+7 more →
PMID: 31270458PMCID: PMC6782071DOI263 citations
With Ronan Chaligne · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauRCRonan ChaligneFGFederico GaitiKGKirill GrigorevDRDavide Risso+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Ronan Chaligne · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauFGFederico GaitiRCRonan ChaligneKGKirill GrigorevDRDavide Risso+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Federico Gaiti · Postdoc mentee
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.
Nature · 2019
DADan Avi LandauKKKyu-Tae KimFGFederico GaitiRCRonan ChaligneKGKirill Grigorev+6 more →
PMID: 31092926PMCID: PMC6533116DOI232 citations
With Kyu-Tae Kim · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauRCRonan ChaligneFGFederico GaitiSKScott KulmWBWendy Béguelin+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Ronan Chaligne · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauFGFederico GaitiSKScott KulmRCRonan ChaligneWBWendy Béguelin+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Federico Gaiti · Postdoc mentee
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nature communications · 2019
DADan Avi LandauKKKyu-Tae KimFGFederico GaitiSKScott KulmRCRonan Chaligne+6 more →
PMID: 31015400PMCID: PMC6478836DOI70 citations
With Kyu-Tae Kim · Postdoc mentee
TARGET-seq Takes Aim at Cancer Evolution through Multi-omics Single-Cell Genotyping and Transcriptomics.
Molecular cell · 2019
DADan Avi LandauRCRonan ChaligneANAnna Nam
PMID: 30901562DOI6 citations
With Ronan Chaligne · Postdoc mentee