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Christopher E Mason, PhD
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Co-authored with Matthew MacKay
Co-authored publications
Christopher E Mason, PhD and Matthew MacKay · 23 publications
CSV
Word
A case for the moral duty of specific human germline genetic engineering
International Journal of Astrobiology
· 2024
Source: Scopus
·
DOI
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Nature communications
· 2024
CE
Christopher E Mason
MM
Matthew Mackay
JK
JangKeun Kim
BT
Braden T Tierney
EO
Eliah Overbey
+12 more →
PMID:
38862516
·
PMCID:
PMC11166952
·
DOI
·
66 citations
·
Abstract
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA).
Nature communications
· 2024
CE
Christopher E Mason
MM
Matthew MacKay
EO
Eliah Overbey
BT
Braden T Tierney
IM
Irina Matei
+5 more →
PMID:
38862509
·
PMCID:
PMC11166662
·
DOI
·
33 citations
·
Abstract
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight.
Nature communications
· 2024
CE
Christopher E Mason
MM
Matthew MacKay
JP
Jiwoon Park
EO
Eliah Overbey
BT
Braden T Tierney
+2 more →
PMID:
38862494
·
PMCID:
PMC11166909
·
DOI
·
33 citations
·
Abstract
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight.
Nature communications
· 2024
CE
Christopher E Mason
MM
Matthew MacKay
NH
Nadia Houerbi
JK
JangKeun Kim
EO
Eliah Overbey
+10 more →
PMID:
38862464
·
PMCID:
PMC11166969
·
DOI
·
36 citations
·
Abstract
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
Nature
· 2024
CE
Christopher E Mason
MM
Matthew MacKay
EO
Eliah Overbey
JK
JangKeun Kim
BT
Braden T Tierney
+25 more →
PMID:
38862028
·
PMCID:
PMC11357981
·
DOI
·
104 citations
·
Abstract
A second space age spanning omics, platforms and medicine across orbits.
Nature
· 2024
CE
Christopher E Mason
MM
Matthew MacKay
MB
Marissa Burke
CC
Christopher Chin
ID
Iwijn De Vlaminck
+13 more →
PMID:
38862027
·
PMCID:
PMC12366838
·
DOI
·
56 citations
·
Abstract
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
iScience
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
KG
Kirill Grigorev
CM
Cem Meydan
FA
Fanny A Pelissier Vatter
+10 more →
PMID:
33376973
·
PMCID:
PMC7756145
·
DOI
·
50 citations
·
Abstract
Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.
Cell
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
SB
Sara Brin Rosenthal
CM
Cem Meydan
JF
Jonathan Foox
PMID:
33242417
·
PMCID:
PMC7870178
·
DOI
·
338 citations
·
Abstract
Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration.
Cell
· 2020
CE
Christopher E Mason
MJ
Matthew J MacKay
DC
Duane C Hassane
CM
Cem Meydan
JF
Jonathan Foox
PMID:
33242416
·
PMCID:
PMC8441988
·
DOI
·
392 citations
·
Abstract
Temporal Telomere and DNA Damage Responses in the Space Radiation Environment.
Cell reports
· 2020
CE
Christopher E Mason
MJ
Matthew J Mackay
JF
Jonathan Foox
KG
Kirill Grigorev
CM
Cem Meydan
PMID:
33242411
·
DOI
·
88 citations
·
Abstract
Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.
Cell reports
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
CC
Christopher Chin
CD
Ceyda Durmaz
AM
Ari M. Melnick
+1 more →
PMID:
33242410
·
PMCID:
PMC8441986
·
DOI
·
70 citations
·
Abstract
Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity.
Cell reports
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
ML
Monica L Gertz
CC
Christopher Chin
DT
Delia Tomoiaga
+2 more →
PMID:
33242408
·
PMCID:
PMC9444344
·
DOI
·
75 citations
·
Abstract
Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight.
Cell reports
· 2020
CE
Christopher E Mason
MJ
Matthew J Mackay
CM
Cem Meydan
PMID:
33242406
·
DOI
·
88 citations
·
Abstract
Clonal Hematopoiesis Before, During, and After Human Spaceflight.
Cell reports
· 2020
CE
Christopher E Mason
MJ
Matthew J MacKay
NM
Nuria Mencia Trinchant
CC
Christopher Chin
JF
Jonathan Foox
+6 more →
PMID:
33242405
·
PMCID:
PMC9398182
·
DOI
·
51 citations
·
Abstract
The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing.
Nature biotechnology
· 2020
CE
Christopher E Mason
MJ
Matthew J MacKay
PMID:
32820257
·
PMCID:
PMC7543743
·
DOI
·
63 citations
Identification of Radioresponsive Genes in Esophageal Cancer from Longitudinal and Single Cell Exome Sequencing.
International journal of radiation oncology, biology, physics
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
JF
Jonathan Foox
PMID:
32561500
·
DOI
·
15 citations
·
Abstract
Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions.
bioRxiv : the preprint server for biology
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
CM
Cem Meydan
DD
David Danko
JF
Jonathan Foox
+19 more →
PMID:
32511352
·
PMCID:
PMC7255793
·
DOI
·
Abstract
The therapeutic landscape for cells engineered with chimeric antigen receptors.
Nature biotechnology
· 2020
CE
Christopher E Mason
MM
Matthew MacKay
JR
Jonathan Rub
GJ
Gail J Roboz
ML
Monica L Guzman
+1 more →
PMID:
31907405
·
DOI
·
212 citations
·
Abstract
Translating current biomedical therapies for long duration, deep space missions.
Precision clinical medicine
· 2019
CE
Christopher E Mason
MM
Matthew MacKay
SI
Sonia Iosim
CW
Craig Westover
PMID:
31886035
·
PMCID:
PMC6927098
·
DOI
·
34 citations
·
Abstract
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Science (New York, N.Y.)
· 2019
CE
Christopher E Mason
MM
Matthew MacKay
FE
Francine E Garrett-Bakelman
CM
Cem Meydan
AM
Augustine M K Choi
+2 more →
PMID:
30975860
·
PMCID:
PMC7580864
·
DOI
·
1,000 citations
·
Abstract
The Impact of Heterogeneity on Single-Cell Sequencing.
Frontiers in genetics
· 2019
CE
Christopher E Mason
MM
Matthew MacKay
AM
Ari M. Melnick
PMID:
30881372
·
PMCID:
PMC6405636
·
DOI
·
104 citations
·
Abstract
The N
6
-methyladenosine (m
6
A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.
Nature medicine
· 2017
CE
Christopher E Mason
MM
Matthew MacKay
BF
Brian F Pickering
SZ
Sara Zaccara
+4 more →
MG
Michael G Kharas
PMID:
28920958
·
PMCID:
PMC5677536
·
DOI
·
1,090 citations
·
Abstract