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Christopher E Mason, PhD
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Co-authored with Jiwoon Park
Co-authored publications
Christopher E Mason, PhD and Jiwoon Park · 29 publications
CSV
Word
Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms.
Leukemia
· 2026
CE
Christopher E Mason
JP
Jiwoon Park
RL
Ralph L Nachman
AK
Aleksandra Kopacz
+18 more →
SP
Sanjay Patel
PMID:
42380663
·
PMCID:
PMC13421341
·
DOI
·
Abstract
The Data Science of Health in Space.
Annual review of biomedical data science
· 2026
CE
Christopher E Mason
JP
Jiwoon Park
JD
Julian Daniel Sunday Willett
JK
JangKeun Kim
TM
Theodore M Nelson
PMID:
42149965
·
DOI
·
Abstract
Spatial transcriptomics atlas of inflammatory bowel disease to guide implementation in research consortiums and clinical trials.
Nature communications
· 2026
CE
Christopher E Mason
JP
Jiwoon Park
PMID:
42049732
·
PMCID:
PMC13328602
·
DOI
·
3 citations
·
Abstract
Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal.
bioRxiv : the preprint server for biology
· 2026
CE
Christopher E Mason
JP
Jiwoon Park
EO
Elif Ozcelik
CD
Ceyda Durmaz
TM
Theodore M Nelson
+2 more →
PMID:
41889866
·
PMCID:
PMC13015288
·
DOI
·
Abstract
Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets.
Nature biotechnology
· 2025
CE
Christopher E Mason
JP
Jiwoon Park
AA
Alicia Alonso
SL
Shauna Lee Houlihan
RE
Robert E. Schwartz
+1 more →
PMID:
41339526
·
PMCID:
PMC13368583
·
DOI
·
18 citations
·
Abstract
Single-cell spatial mapping reveals dynamic bone marrow microarchitectural alterations and enhances clinical diagnostics in MDS.
bioRxiv : the preprint server for biology
· 2025
CE
Christopher E Mason
JP
Jiwoon Park
AK
Aleksandra Kopacz
CU
Caitlin Unkenholz
+13 more →
SP
Sanjay Patel
PMID:
41279873
·
PMCID:
PMC12632391
·
DOI
·
Abstract
Multi-Omics Profiling of Individuals Sustaining Extreme Physical Stressors.
Life (Basel, Switzerland)
· 2025
CE
Christopher E Mason
JP
Jiwoon Park
RC
Robert Chen
TM
Theodore M Nelson
PMID:
41010319
·
PMCID:
PMC12471032
·
DOI
·
2 citations
·
Abstract
The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.
bioRxiv : the preprint server for biology
· 2025
CE
Christopher E Mason
JP
Jiwoon Park
EP
Erika Patel
EO
Elif Ozcelik
NB
Nicholas Bartelo
+14 more →
PMID:
40611896
·
PMCID:
PMC12224548
·
DOI
·
Abstract
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
AC
Amy Chadburn
AB
Alain Borczuk
SS
Saloni Sinha
+6 more →
PMID:
39602262
·
PMCID:
PMC11626201
·
DOI
·
21 citations
·
Abstract
Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer.
Cancer cell
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
CA
Caitlin A McIntyre
AG
Adrien Grimont
+16 more →
RC
Rohit Chandwani
PMID:
39214094
·
PMCID:
PMC11419252
·
DOI
·
74 citations
·
Abstract
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.
Communications medicine
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
CM
Cem Meydan
EO
Eliah Overbey
CC
Christopher Chin
PMID:
38862781
·
PMCID:
PMC11166967
·
DOI
·
8 citations
·
Abstract
Spaceflight induces changes in gene expression profiles linked to insulin and estrogen.
Communications biology
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
JK
JangKeun Kim
EO
Eliah Overbey
PMID:
38862620
·
PMCID:
PMC11166981
·
DOI
·
31 citations
·
Abstract
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight.
Nature microbiology
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
BT
Braden T Tierney
JK
JangKeun Kim
EO
Eliah Overbey
+7 more →
PMID:
38862604
·
PMCID:
PMC11222149
·
DOI
·
68 citations
·
Abstract
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
Nature communications
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
JK
JangKeun Kim
EO
Eliah Overbey
CM
Cem Meydan
+1 more →
PMID:
38862542
·
PMCID:
PMC11166944
·
DOI
·
22 citations
·
Abstract
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Nature communications
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
JK
JangKeun Kim
BT
Braden T Tierney
EO
Eliah Overbey
+12 more →
PMID:
38862516
·
PMCID:
PMC11166952
·
DOI
·
66 citations
·
Abstract
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight.
Nature communications
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
EO
Eliah Overbey
BT
Braden T Tierney
MM
Matthew MacKay
+2 more →
PMID:
38862494
·
PMCID:
PMC11166909
·
DOI
·
33 citations
·
Abstract
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
Nature
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
EO
Eliah Overbey
JK
JangKeun Kim
BT
Braden T Tierney
+25 more →
PMID:
38862028
·
PMCID:
PMC11357981
·
DOI
·
104 citations
·
Abstract
A second space age spanning omics, platforms and medicine across orbits.
Nature
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
MB
Marissa Burke
CC
Christopher Chin
ID
Iwijn De Vlaminck
+13 more →
PMID:
38862027
·
PMCID:
PMC12366838
·
DOI
·
56 citations
·
Abstract
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew.
Nature
· 2024
CE
Christopher E Mason
JP
Jiwoon Park
EO
Eliah Overbey
CM
Cem Meydan
BT
Braden Tierney
+9 more →
PMID:
38862026
·
PMCID:
PMC11357997
·
DOI
·
52 citations
·
Abstract
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection.
European journal of human genetics : EJHG
· 2023
CE
Christopher E Mason
JP
Jiwoon Park
RE
Robert E. Schwartz
PMID:
37938797
·
PMCID:
PMC10772081
·
DOI
·
49 citations
·
Abstract
Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation.
Research square
· 2023
CE
Christopher E Mason
JP
Jiwoon Park
BT
Braden T Tierney
EO
Eliah Overbey
MS
Maria Sierra
+5 more →
PMID:
37886447
·
PMCID:
PMC10602132
·
DOI
·
Abstract
Elevated A-to-I RNA editing in COVID-19 infected individuals.
NAR genomics and bioinformatics
· 2023
CE
Christopher E Mason
JP
Jiwoon Park
CM
Cem Meydan
PMID:
37859800
·
PMCID:
PMC10583280
·
DOI
·
14 citations
·
Abstract
More than a Feeling: Dermatological Changes Impacted by Spaceflight.
Research square
· 2023
CE
Christopher E Mason
JP
Jiwoon Park
CM
Cem Meydan
EO
Eliah Overbey
JK
JangKeun Kim
PMID:
36798347
·
PMCID:
PMC9934743
·
DOI
·
28,117 citations
·
Abstract
Spatial omics technologies at multimodal and single cell/subcellular level.
Genome biology
· 2022
CE
Christopher E Mason
JP
Jiwoon Park
JK
Junbum Kim
CM
Charles M. Rice
OE
Olivier Elemento
PMID:
36514162
·
PMCID:
PMC9746133
·
DOI
·
113 citations
·
Abstract
Challenges and considerations for single-cell and spatially resolved transcriptomics sample collection during spaceflight.
Cell reports methods
· 2022
CE
Christopher E Mason
JP
Jiwoon Park
EO
Eliah Overbey
DC
Dawn Chirko
PMID:
36452864
·
PMCID:
PMC9701605
·
DOI
·
17 citations
·
Abstract
IL-6/STAT3 axis dictates the PNPLA3-mediated susceptibility to non-alcoholic fatty liver disease.
Journal of hepatology
· 2022
CE
Christopher E Mason
JP
Jiwoon Park
CM
Charles M. Rice
PMID:
36049612
·
PMCID:
PMC9772150
·
DOI
·
135 citations
·
Abstract
System-wide transcriptome damage and tissue identity loss in COVID-19 patients.
Cell reports. Medicine
· 2022
CE
Christopher E Mason
JP
Jiwoon Park
DC
David C Danko
AF
André F Rendeiro
PV
Priya Velu
+12 more →
PMID:
35233546
·
PMCID:
PMC8784611
·
DOI
·
34 citations
·
Abstract
The spatial landscape of lung pathology during COVID-19 progression.
Nature
· 2021
CE
Christopher E Mason
JP
Jiwoon Park
AF
André F Rendeiro
JK
Junbum Kim
+4 more →
RE
Robert E. Schwartz
PMID:
33780969
·
PMCID:
PMC8204801
·
DOI
·
295 citations
·
Abstract
Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.
bioRxiv : the preprint server for biology
· 2021
CE
Christopher E Mason
JP
Jiwoon Park
DD
David Danko
AC
Arryn Craney
PV
Priya Velu
+13 more →
PMID:
33758858
·
PMCID:
PMC7987017
·
DOI
·
Abstract