Co-authored publications with mentees

PhD mentee

• The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus.

  eLife · 2024

  CPCarl P. BlobelJLJose LoraTMThomas Morgan LiVZVictoria Zyulina+8 more →TTTheresa T. Lu

  PMID: 38860651·PMCID: PMC11213570·DOI·3 citations·Abstract

  With Jose Lora · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022

• Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.

  The Journal of biological chemistry · 2021

  CPCarl P. BlobelJLJose LoraTMThomas M LiTTTheresa T. Lu

  PMID: 33957124·PMCID: PMC8191336·DOI·12 citations·Abstract

  With Jose Lora · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022

• Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.

  International journal of molecular sciences · 2021

  CPCarl P. BlobelJLJose LoraRORolake O Alabi

  PMID: 33673337·PMCID: PMC7918056·DOI·18 citations·Abstract

  With Jose Lora · Physiology, Biophysics & Systems Biology (PhD) · Class of 2022

• Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice.

  Angiogenesis · 2020

  CPCarl P. BlobelNLNicole Lustgarten GuahmichDMDylan McNallyDRDavid RedmondHSHeidi Stuhlmann+1 more →

  PMID: 32385775·PMCID: PMC8603441·DOI·19 citations·Abstract

  With Nicole Lustgarten Guahmich · Physiology, Biophysics & Systems Biology (PhD) · Class of 2020

• Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020

  CPCarl P. BlobelBTBeiyu TangHWHarel Weinstein

  PMID: 32103528·PMCID: PMC7316530·DOI·31 citations·Abstract

  With Beiyu Tang · Pharmacology (PhD) · Class of 2020

• ADAM10 controls the differentiation of the coronary arterial endothelium.

  Angiogenesis · 2018

  CPCarl P. BlobelNLNicole Lustgarten GuahmichGFGregory FarberSMSébastien MonetteSCScott C Blanchard+1 more →

  PMID: 30446855·PMCID: PMC6475616·DOI·38 citations·Abstract

  With Nicole Lustgarten Guahmich · Physiology, Biophysics & Systems Biology (PhD) · Class of 2020

• The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.

  Journal of cellular physiology · 2017

  CPCarl P. BlobelXLXue Li

  PMID: 28703301·PMCID: PMC5705578·DOI·20 citations·Abstract

  With Xue Li · Cell & Developmental Biology (PhD) · Class of 2016

• Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.

  Journal of cell science · 2017

  CPCarl P. BlobelXLXue LiSMSébastien MonetteHWHarel Weinstein

  PMID: 28104813·PMCID: PMC5358332·DOI·39 citations·Abstract

  With Xue Li · Cell & Developmental Biology (PhD) · Class of 2016

• iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.

  Proceedings of the National Academy of Sciences of the United States of America · 2015

  CPCarl P. BlobelXLXue LiSMSébastien MonettePDPriya Darshinee A IssureeJEJane E Salmon

  PMID: 25918388·PMCID: PMC4434755·DOI·134 citations·Abstract

  With Xue Li · Cell & Developmental Biology (PhD) · Class of 2016

• iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.

  Proceedings of the National Academy of Sciences of the United States of America · 2013

  CPCarl P. BlobelXLXue LiPDPriya Darshinee A IssureeSASadaf Amin

  PMID: 23801765·PMCID: PMC3710827·DOI·149 citations·Abstract

  With Xue Li · Cell & Developmental Biology (PhD) · Class of 2016