Carl P. Blobel, MD, PhD

Publications

151

Funding

6 View NIH portfolio on RePORTER ↗

Active

1 grant

PI
Role of iRhoms and ADAM17 in EGFR and TNFalpha signaling
NIGMS · 2020–2025 · via NIH RePORTER
R35GM134907-05

Completed grants (5)

PI
iRhoms 1 and 2: Key regulators of ADAM17-dependent EGFR signaling
NIGMS · 2002–2020 · via NIH RePORTER
R01GM064750-17
KP
The Role of Endothelial Cell ADAM10/Notch Signaling in the Development of the Coronary Vascular Niche
American Heart Association · 2017–2018Fellowship
AHA 17PRE33380001
PI
Role of ADAMs 9 and 15 in Proliferative Retinopathy
NEI · 2004–2010 · via NIH RePORTER
R01EY015719-06S1
PI
Matrix Metalloproteinases Gordon Conference
NCI · 2005–2010 · via NIH RePORTER
R13CA115182-03
PI
METALLOPROTEASE DISINTEGRIN MDC9
NIGMS · 1999–2004 · via NIH RePORTER
R01GM058668-04

Honors & distinctions

Member · Association of American Physicians

Mentoring

6 All publications with mentees →

XL
Xue Li
Cell & Developmental Biology (PhD) · Class of 2016
- The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
  Journal of cellular physiology · 2017
- Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
  Journal of cell science · 2017
- iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
  Proceedings of the National Academy of Sciences of the United States of America · 2015
View all 4 →
JL
Jose Lora
Physiology, Biophysics & Systems Biology (PhD) · Class of 2022
- The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus.
  eLife · 2024
- Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
  The Journal of biological chemistry · 2021
- Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.
  International journal of molecular sciences · 2021
View all 3 →
NL
Nicole Lustgarten Guahmich
Physiology, Biophysics & Systems Biology (PhD) · Class of 2020
- Endothelial deletion of ADAM10, a key regulator of Notch signaling, causes impaired decidualization and reduced fertility in female mice.
  Angiogenesis · 2020
- ADAM10 controls the differentiation of the coronary arterial endothelium.
  Angiogenesis · 2018
View all 2 →
BT
Beiyu Tang
Pharmacology (PhD) · Class of 2020
- Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
View all 1 →
YZ
Yi Zhao
Cell & Developmental Biology (PhD) · Class of 2023
RF
Robert Frawley
Physiology, Biophysics & Systems Biology (PhD) · Class of 2016

External relationships

Professional Services

Technical University Munich