Michelle S. Bradbury, PhD, MD

Professor of Pharmacology

Pharmacology

Contact & profiles

Appointments

Professor of PharmacologyPrimary
Pharmacology · 2026–
Professor of Neuroscience
Brain and Mind Research · 2024–
Professor of Radiology in Radiation Oncology
Radiation Oncology · 2024–
Physician
NewYork-Presbyterian Hospital

Past Appointments

Endowed Professor of Imaging Research in Radiology
Radiology · 2024–2026
Professor of Radiology
Radiology · 2023–2026
Professor of Radiology
Radiology · 2017–2023

Show all 5

Associate Professor of Radiology
Radiology · 2012–2017
Assistant Professor of Radiology
Radiology · 2006–2012

Centers

Clinical & Translational Science Center
Sandra and Edward Meyer Cancer Centerresearch
Cancer Therapeutics

Education

M.D., Medicine
George Washington University School of Medicine and Health Sciences, 1997
Ph.D.
Massachusetts Institute of Technology, 1993
M.S.
University of Maryland, 1986
B.A.
University of Pennsylvania, 1982

Highlights

1
Nature nanotechnology · 2025
FSFabio Socciarelli MPMiles Pourbaghi TMTaha Merghoub JDJedd D Wolchok MSMichelle S. Bradbury
PMID: 41461940PMCID: PMC12916478DOISenior author18 citations
2
Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
CRCharles Rudin MSMichelle S. Bradbury
PMID: 35499557PMCID: PMC9250642DOISenior author21 citations
3
Advanced therapeutics · 2022
MSMichelle S. Bradbury
PMID: 37007587PMCID: PMC10061546DOISenior author

Publications

Funding

9 View NIH portfolio on RePORTER ↗

Active

5 grants

PI
Targeting Inflammatory Pathways in Breast Cancer Brain Metastases for the Treatment of Edema and Radiation Necrosis Using Anti-VEGF Ultrasmall Particle Therapy
U.S. Department of Defense · 2025–2028
HT9425-25-1-0084
PI
Ultrasmall PSMA-Targeted Particle Radiotherapy for Regulating the Immunosuppressive Prostate Cancer Tumor Microenvironment and Enhancing Treatment Efficacy
U.S. Department of Defense · 2023–2027
HT9425-23-1-0631
PI
Reprogramming of IL-I Driven Inflammation and Immune Suppression in Breast Cancer and Clonal Hematopoiesis Models Using Targeted Ultrasmall Particle Therapies.
Memorial Sloan Kettering Cancer Center · 2025–2027
MSKCC 254279-02
PI
Ultrasmall particle-based solutions for inducing ferroptosis and improving anti-tumor immune responses in cancer
National Cancer Institute · 2023–2027
R01CA253658-05
PI
Molecular Phenotyping and Image-Guidance for Surgical Treatment of High-Risk Prostate Cancer Using Ultrasmall Silica Nanoparticles
National Cancer Institute · 2023–2026
R01CA243085-05

Completed grants (4)

MPI
Administrative Core
NCI · 2015–2021 · via NIH RePORTER
U54CA199081-05
PI
Renally Excreted Multimodal Core-Shell Silica Nanoparticles as Tumor-Selective Ra
NCI · 2012–2018 · via NIH RePORTER
R01CA161280-05
PI
MRI-PET Guided Stereotactic Biopsy of High Grade Gliomas
NCI · 2009–2012 · via NIH RePORTER
R21CA137896-02
PI
Molecular Neuroimaging Symposium
NIBIB · 2010–2011 · via NIH RePORTER
R13EB011853-01

Clinical research

Active

1 study

PI
Molecular Phenotyping and Image-Guided Surgical Treatment of Prostate Cancer Using Ultrasmall Silica Nanoparticles
PHASE1 · Memorial Sloan Kettering Cancer Center · OPEN TO ACCRUAL (as of 2024)
Prostate Cancer
NCT04167969

News mentions

1 View all WCM news ↗

Experimental Treatment Directly Kills Prostate Tumor Cells While Reawakening Antitumor Immunity
June 15, 2026
Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing anti-tumor immunity, according to a preclinical study led by investigators at Weill Cornell Medicine and the Cornell Duffield College of Engineering.

Media highlights

Nanoparticles Overcome Resistance In Prostate Cancer
Oncology Times · September 1, 2026

Mentoring

5 All publications with mentees →

NS
Nabil Siddiqui
Postdoc mentee · 2023–2026
- Reprogramming of TLR-Ferroptosis Signaling and Immunometabolic Pathways Overcomes Myeloid Suppression to Improve Checkpoint Blockade in Prostate Cancer.
  Cancer research · 2026
- Advancements in Intraoperative Imaging for Enhanced Surgical Precision.
  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
- Next-Generation Multifunctional Imaging Tools for Precision Surgical Oncology
  2026
View all 4 →
GD
Gabriel De Leon
Postdoc mentee · 2023–2025
- Reprogramming of TLR-Ferroptosis Signaling and Immunometabolic Pathways Overcomes Myeloid Suppression to Improve Checkpoint Blockade in Prostate Cancer.
  Cancer research · 2026
- An ultrasmall core-shell silica nanoparticle improves antitumour immunity and survival by remodelling suppressive melanoma microenvironments.
  Nature nanotechnology · 2025
- Engineered Ultrasmall Nanoparticle Drug-Immune Conjugates with "Hit and Run" Tumor Delivery to Eradicate Gastric Cancer.
  Advanced therapeutics · 2022
View all 3 →
MP
Miles Pourbaghi
Postdoc mentee · since 2026
- Advancements in Intraoperative Imaging for Enhanced Surgical Precision.
  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
- An ultrasmall core-shell silica nanoparticle improves antitumour immunity and survival by remodelling suppressive melanoma microenvironments.
  Nature nanotechnology · 2025
View all 2 →
MA
Mohammed Ala Ghrib
Postdoc mentee · since 2026
DP
Daniel Penarete Acosta
Postdoc mentee · 2023–2023