Overview
Investigating the endocrine functions of the kidney has been central to my research - spanning renal erythropoietin production, salt handling, prostaglandin signaling and vitamin D metabolism.
My current research focuses investigating on the relationship of FGF23 and vitamin D in chronic kidney disease (CKD) outside the kidneys in important vitamin D target organs like the intestines, parathyroids and bone.
Vitamin D metabolism is severely disrupted in patients with CKD and leads to secondary hyperparathyroidism and mineral bone disorder, increasing mortality and fracture-risk in CKD patients.
Defining new treatment options for patients with CKD by utilizing local vitamin D regulatory mechanisms outside the kidney will enable us to improve not only the quality of life, but also outcomes in CKD patients.
Highlights
- 1The Journal of clinical investigation · 2024
- 2Kidney international · 2025
- 3
Publications
Funding
Active
1 grant- PIASN 255580-01Targeting CYP24A1 in the parathyroid glands as a novel treatment of secondary hyperparathyroidism in chronic kidney diseaseAmerican Society of Nephrology Inc · 2026–2028