Method

iPSC-derived cell models

Differentiated cell types and organoids derived from induced pluripotent stem cells, providing patient-specific or isogenic human cellular models for mechanistic studies and drug screening.

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Scholars using this

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SC
Shuibing ChenKilts Family Professor of Surgery
SC
Shuibing ChenKilts Family Professor of Surgery
LG
Li GanDirector, Helen and Robert Appel Alzheimer’s Disease Research Institute
LG
Li GanDirector, Helen and Robert Appel Alzheimer’s Disease Research Institute
SA
Susan A. GauthierFinbar and Marianne Kenny Professor in Neurology
SA
Susan A. GauthierFinbar and Marianne Kenny Professor in Neurology
BK
Bernhard KuhnChief, Cardiology (Pediatrics)
BK
Bernhard KuhnChief, Cardiology (Pediatrics)
LF
Li FanAssistant Professor of Research in Neuroscience
LF
Li FanAssistant Professor of Research in Neuroscience
GM
Giovanni ManfrediFinbar and Marianne Kenny Professor in Clinical and Research Neurology
GM
Giovanni ManfrediFinbar and Marianne Kenny Professor in Clinical and Research Neurology

Spotlight

iPSC-derived cell models

MMMatthew MahoneyYFYilin FengNFNessa FoxeSGShiaoching Gong+2 more →LGLi Gan

Neuron · 2026

iPSC-derived cell models

SNSarah Naguib SGShiaoching Gong LFLi Fan LGLi Gan

Molecular neurodegeneration · 2026

iPSC-derived cell models

XZXiaoshan Zhang SCShuibing Chen

Cell reports · 2025

View all 17 publications →

iPSC-derived cell models

Scholars using this

Spotlight

Publications

Publications

iPSC-derived cell models

Scholars using this

Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction.

Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice.

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals.