Overview

1. 1
   Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements.

   Aging cell · 2024

   L(Lishomwa (Lish) NdhlovuMLMatthew Lewis BendallDNDouglas NixonMJMichael Jay Corley

   PMID: 39092674·PMCID: PMC11464121·DOI·First author·27 citations·Abstract
2. 2
   Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.

   Journal of leukocyte biology · 2021

   MJMichael Jay CorleyTPThomas PremeauxSTStephen Tung YeungRERobert E. SchwartzL(Lishomwa (Lish) Ndhlovu

   PMID: 33464637·PMCID: PMC8013321·DOI·Senior author·114 citations·Abstract
3. 3
   Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART.

   PLoS pathogens · 2021

   MJMichael Jay CorleyL(Lishomwa (Lish) Ndhlovu

   PMID: 34388205·PMCID: PMC8386872·DOI·Senior author·25 citations·Abstract

• KP

  Columbia University-Weill Cornell Medicine CFAR (CU-WCM CFAR)

  National Institute of Allergy and Infectious Diseases · 2026–2031 · via Columbia University

  Abstract

  P30AI191337-01A1
• Sub-PI

  Characterization of Allogeneic T cells mediating HIV cure

  National Institute of Allergy and Infectious Diseases · 2025–2030 · via Oregon Health & Science University

  Abstract

  R37AI189285-02
• PI

  New York-New Jersey Center for Actionable NeuroHIV Biomarkers and Integrated Omics (NYJ-CAN-BIO)

  National Institute of Mental Health · 2026–2030

  Abstract

  P30MH144896-01
• MPI

  Single cell dark matter in the context of HIV and substance use

  National Institute on Drug Abuse · 2025–2030 · via The Feinstein Institute for Medical Research

  Abstract

  R01DA063076-02
• Sub-PI

  Modulation of Galectin-9 to Target HIV Persistence

  National Institute of Allergy and Infectious Diseases · 2024–2029 · via Vitalant Research Institute

  Abstract & 1 publication

  R01AI184421-02
• Sub-PI

  Extracellular Vesicles as Biomarkers and Therapeutic Targets for Atherosclerotic Cardiovascular Disease in Persons Living with HIV

  National Heart, Lung, and Blood Institute · 2024–2029 · via Vitalant Research Institute

  Abstract

  DP1HL174193-03
• Sub-PI

  Defining the Immunogenicity and Efficacy of a Durable BCG Vaccine Strategy Optimized for Preventing TB in Pediatric HIV Infection

  National Institute of Allergy and Infectious Diseases · 2023–2028 · via University of Pittsburgh

  Abstract

  R01AI179324-04
• Sub-PI

  Relationship between methamphetamine use, viral reservoir dynamics and clinical progression in treated HIV infection

  National Institute on Drug Abuse · 2023–2028 · via University of Miami

  Abstract

  R01DA058437-03
• MPI

  Elucidating single cell changes in neurogenic brain regions during HIV and cannabinoid exposure

  National Institute on Drug Abuse · 2023–2028

  Abstract & 9 publications

  U01DA058527-04
• Sub-PI

  Targeting HIV-specific CAR T cells to the gut for the durable remission of HIV

  National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2028 · via University of Minnesota

  Abstract & 1 publication

  R01DK133907-03
• PI

  LYMPHATIC IMAGING, GENOMIC AND PHENOTYPING TECHNOLOGIES (LIGHT) / LYMPHATIC DISEASE ADVANCEMENTS WITH NANOTECHNOLOGY, TRANSLATIONAL EPIGENETICS, AND RESEARCH IN GENETICS (LANTERN)

  Advanced Research Projects Agency for Health · 2025–2027

  AY2AX000080-01
• Co-I

  Cardiac Magnetic Resonance for Tissue Characterization Based Risk Stratification of Cardiopulmonary Symptoms, Effort Tolerance, and Prognosis Among COVID-19 Survivors

  National Heart, Lung, and Blood Institute · 2021–2027

  Abstract & 1 publication

  R01HL159055-01
• Sub-PI

  HOPE - HIV Obstruction by Programmed Epigenetics

  National Institute of Allergy and Infectious Diseases · 2021–2027 · via University of California, San Francisco· 2 renewals

  Abstract & 11 publications

  UM1AI164559-05
• Co-I

  REACH: Research Enterprise to Advance a Cure for HIV

  National Institute of Allergy and Infectious Diseases · 2021–2027· 2 renewals

  Abstract & 4 publications

  UM1AI164565-06
• MPI

  Integrative Single Cell isoform and chromatin accessibility Mapping of Chronic Opioid Exposure in Cognitive Brain Areas in HIV

  National Institute on Drug Abuse · 2021–2027· 2 renewals

  Abstract & 10 publications

  U01DA053625-03S1
• Sub-PI

  Impact of IL-15 immunotherapy on tissue-specific CD8 T cells to reduce the CNS HIV reservoir seeding and persistence

  National Institute of Mental Health · 2023–2027 · via Henry M. Jackson Foundation for the Advancement of Military Medicine

  Abstract & 6 publications

  R01MH130197-03
• Sub-PI

  Targeting HIV reservoirs in the CNS with CAR/CXCR5 T cells for the long-term remission of HIV.

  National Institute of Mental Health · 2022–2027 · via University of Minnesota

  Abstract & 1 publication

  R01MH130177-05
• Sub-PI

  Study of NeuroHIV Cure Consortium. (Protocols: RV254, RV397, RV398, RV405, RV412 and non-human primate viral eradication programs)

  United States Army Medical Research and Materiel Command · 2024–2026 · via Henry M. Jackson Foundation for the Advancement of Military Medicine

  HT94252430004
• Sub-PI

  A nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearance

  National Institute of Allergy and Infectious Diseases · 2022–2026 · via Oregon Health & Science University

  Abstract & 5 publications

  R01AI129703-09
• MPI

  Development of Brain Organoids to Study the Impact of HIV-1, Drugs of Abuse and Aging on Cognitive Impairment

  National Institute on Drug Abuse · 2020–2026 · via The Feinstein Institute for Medical Research· 2 renewals

  Abstract & 10 publications

  R01DA052027-06
• PI

  Harnessing Single Cell Epigenome-wide profiling of Myeloid cells to Compare and Contrast Alzheimer's from HIV-Associated Cognitive Dysfunction

  National Institute on Aging · 2020–2026· 3 renewals

  Abstract & 11 publications

  R01AG063846-05

• Member · Association of American Physicians

• PI

  Lymphatic Imaging, Genomic and pHenotyping Technologies (LIGHT) / Lymphatic Disease Advancements with Nanotechnology, Translational Epigenetics, and Research in Genetics (LANTERN)

  Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2026)
• PI

  Harnessing Single Cell Epigenome-wide profiling of Myeloid cells to Compare and Contrast Alzheimer's from HIV-Associated Cognitive Dysfunction (AHEAD STUDY)

  Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2021)

• HERV-K Expression as a Biomarker for Predicting Immunotherapy Response

  Provisional filedPoC Data·Overview

  11459
• Retroelement-Based Epigenetic Clock as a Biomarker of Biological Aging

  PCT filedPoC Data·PMID 39092674·Overview

• Weill Cornell Medicine Receives $3 Million to Launch Research Center Focused on HIV’s Effects on the Brain

  September 14, 2026

  Weill Cornell Medicine and Rutgers Health in New Brunswick have received a four-year, $3 million grant from the National Institute of Mental Health (NIMH) to build the infrastructure and resources that will accelerate discoveries about HIV-associated brain injury.

• Weill Cornell Medicine Receives Funding to Develop Diagnostic Toolbox for Lymphatic Disease

  January 20, 2026

  Weill Cornell Medicine has received a $5.2 million, initial two-year award from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics, and pHenotyping Technologies (LIGHT) program to develop a comprehensive and innovative approach to diagnosing lymphatic disease.

• MERIT Grant Awarded to Study Cure for HIV

  August 28, 2025

  A scientific team co-led by Dr. Lishomwa Ndhlovu at Weill Cornell Medicine has received an NIH MERIT Award to provide long-term grant support to study several people who have managed to clear HIV after a stem cell transplant and those who did not.

• Weill Cornell Medicine Faculty Inducted into Association of American Physicians

  April 28, 2025

  Three distinguished Weill Cornell Medicine physician-scientists, Dr. Matthew Greenblatt, Dr. Lishomwa Ndhlovu and Dr. Sallie Permar, have been elected to the prestigious Association of American Physicians (AAP).

• Study Finds Potential Link Between DNA Markers and Aging Process

  August 19, 2024

  Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

• Weill Cornell And Rutgers Get $3 Million To Study HIV’s Effects On The Brain

  FingerLakes1.com · September 30, 2026
• Rutgers, Weill Cornell Medicine Awarded $3M To Study HIV’s Effects On The Brain

  ROI-NJ · September 24, 2026

• AP

  Alina Pang

  Postdoc mentee · 2025–2025

  21 co-pubs
  • Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People With HIV.
    The Journal of infectious diseases · 2025
  • Combined single-cell profiling of chromatin-transcriptome and splicing across brain cell types, regions and disease state.
    Nature biotechnology · 2025
  • Sex differences in epigenetic ageing for older people living with HIV.
    EBioMedicine · 2025

  View all 21 →
• PM

  Preeti Moar

  Postdoc mentee · 2022–2024

  4 co-pubs
  • Altered distribution of tissue galectins correlates with mucosal dysregulation in SIV infection.
    Journal of immunology (Baltimore, Md. : 1950) · 2026
  • Alterations in circulating immunoregulatory proteins discriminate poor CD4 T lymphocyte trajectories in people with HIV on suppressive antiretroviral therapy.
    mBio · 2024
  • Plasma galectin-9 relates to cognitive performance and inflammation among adolescents with vertically acquired HIV.
    AIDS (London, England) · 2024

  View all 4 →
• CT

  Citlalli Tomas Baltazar

  Neuroscience (PhD)
• MD

  Meghan Davis

  MD-PhD WGS Neuroscience (PhD)