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Overview

Dr. Julianne Imperato-McGinley is the Associate Dean for Translational Research and Educational Training, the Director and Principal Investigator of the Clinical and Translational Science Center (CTSC),  the Abby Rockefeller Mauzé Distinguished Professor of Medicine in Endocrinology, and Chief of the Division of Endocrinology, Diabetes and Metabolism at Weill Cornell Medical College (WCMC).

A clinical and translational researcher with over 30 years of NIH funding Dr. Imperato-McGinley first published her landmark paper in Science in 1974. She defined a previously unrecognized clinical disorder - inherited 5α-reductase deficiency.  Eventually the clinical implications of her research were translated into treatment of human disease and led to the development of the first medical therapy (finasteride) for prostate enlargement, and subsequently, for the treatment of male-pattern baldness.  Her classic studies, involving androgen physiology and its effect on the body and brain were the first to significantly challenge the widely held view that gender is socially acquired.  Much of her work is included in standard textbooks of endocrinology, psychology, urology and medicine.

Among her honors and awards, she is an elected member of the American Association of Physicians for her contributions to clinical research and an EH Ahrens Awardee for Excellence in Clinical Research. She has a long history of training and mentoring students from high school to MDs in fellowship training, particularly second-year endocrine fellows in their patient-oriented research projects. A recipient of two Empire State Investigator Grants for mentoring, and a former PI on a T32 endocrine training grant, she worked with the Dean of Weill Cornell to establish a prize for excellence in clinical research and served on the Medical Student Research Awards Committee for over 10 years and as chairperson for 4 years.  

Highlights

  1. 1
    Journal of clinical and translational science · 2025
    PMID: 40201657PMCID: PMC11975767DOISenior author

Publications

108 publications

Active

2 grants
  • KP
    Research Training in Endocrinology and Metabolism
    National Institute of Diabetes and Digestive and Kidney Diseases · 2023–2028Training
    T32DK131957-01A1
  • MPI
    Clinical and Translational Science Center - UL1
    National Center for Advancing Translational Sciences · 2017–2027· 4 renewals
    UL1TR002384-10
Completed grants (24)
  • MPI
    Clinical and Translational Science Center- Institutional CTSC Internal Funding UL1
    CTSC Cost Share · 2017–2022
    CTSC Internal Funding UL1
  • KP
    Clinical and Translational Science Center - KL2
    National Center for Advancing Translational Sciences · 2017–2022Career
    KL2TR002385-02
  • Co-I
    Clinical and Translational Science Center - TL1
    National Center for Advancing Translational Sciences · 2017–2022Training
    TL1TR002386-01
  • MPI
    An Innovative Wearable Sensor For The Early Detection and Prevention Of Fatal Opioid Overdose
    National Institute on Drug Abuse · 2020–2022
    R21DA049566-02
  • PI
    Anne Marie Weber-Main Consultant Agreement
    University of Minnesota · 2018–2019Contract
    CA 192141-01
  • PI
    Consulting Agreement
    Amy Markowitz, JD · 2018–2019Contract
    CA 191598-01
  • PI
    Esam El-Fakahany Consultant Agreement
    University of Minnesota · 2018–2019Contract
    CA 192140-01
  • PI
    Consulting Agreement
    Amy Markowitz, JD · 2018–2019Contract
    CA 191596-01
  • PI
    Consulting Agreement
    West Virginia Clinical and Translational Science Institute · 2018–2019Contract
    CA 190852-01
  • PI
    Consulting Agreement
    University of Massachusetts Medical School · 2018–2019Contract
    CA 190851-01
  • KP
    PCORI NYC-CDRN, Phase II
    Patient-Centered Outcomes Research Institute · 2015–2019
    CDRN-1306-03961-PII
  • PI
    Clinical and Translational Science Center (KL2) - Career Award
    National Center for Advancing Translational Sciences · 2012–2017Career
    KL2TR000458-08
  • PI
    Clinical and Translational Science Center
    NCATS · 2007–2017 · via NIH RePORTER
    UL1TR000457-10
  • PI
    Clinical and Translational Science Center
    NCATS · 2007–2017 · via NIH RePORTER
    TL1TR000459-10
  • Sub-PI
    CTSC: Metabolic Conditionality of Antibiotic Resistance in Clinical MRSA Strains
    National Center for Advancing Translational Sciences · 2012–2014 · via Rockefeller University
    No publications yet
    UL1TR000043-07S1E
  • PI
    ENDOCRINE RESEARCH TRAINING GRANT
    NIDDK · 1978–2013 · via NIH RePORTER
    T32DK007313-33
  • PI
    CTSA INFRASTRUCTURE FOR AIDS RESEARCH
    NCRR · 2007–2012 · via NIH RePORTER
    UL1RR024996-05
  • PI
    Clinical and Translational Science Center (KL2)
    NCRR · 2007–2012 · via NIH RePORTER
    KL2RR024997-05
  • PI
    Clinical and Translational Science Center (TL1)
    NCRR · 2007–2012 · via NIH RePORTER
    TL1RR024998-05
  • PI
    K30: Clinical Research Curriculum Award - WMC
    NCRR · 2005–2010 · via NIH RePORTER
    K30RR022250-03
  • PI
    Cognition, Androgens and Sexual Dimorphism
    NIMH · 2003–2010 · via NIH RePORTER
    R01MH064624-05
  • PI
    PLANNING GRANT FOR THE INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARD
    NCRR · 2006–2007 · via NIH RePORTER
    No publications yet
    P20RR023503-01
  • MPI
    ANDROGENS AND COGNITIVE FUNCTION
    NCRR · 2004–2007 · via NIH RePORTER
    M01RR000047-47
  • PI
    ANDROGENS REGULATE IGF PATHWAY AND PROSTATE DISEASES
    NCI · 2000–2003 · via NIH RePORTER
    R03CA085435-02

Honors & distinctions

2 honors
  • Joan and Sanford I. Weill Exemplary Achievement Award · Weill Cornell Medicine · 2023
  • Member · Association of American Physicians

Clinical research

2 studies
Completed & closed trials (2)
  • PI
    Testing of a wearable near-field sensing (NCS) device to detect respiratory rate for ultimate use in persons with opioid use disorders
    Clinical Translational Science Center (Weill Cornell) · IRB STUDY CLOSURE (as of 2023)
  • PI
    Comparison of a wearable NCS device for monitoring respiratory depression for use in persons with opioid use disorders
    Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2023)

Available technologies

News mentions

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Media highlights

1 clip