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ScholarsBetaWeill Cornell Medicine

Highlights

  1. 1
    Nature aging · 2024
    JTJessica Tyler
    PMID: 39587368PMCID: PMC11964297DOISenior author12 citations
  2. 2
    eLife · 2018
    JTJessica Tyler
    PMID: 30117416PMCID: PMC6097839DOISenior author64 citations
  3. 3
    eLife · 2022
    JTJessica Tyler
    PMID: 35575473PMCID: PMC9122494DOISenior author16 citations

Publications

114 publications

Funding

14 grantsView NIH portfolio on RePORTER ↗

Active

3 grants
  • PI
    Discovering how autophagy is sufficient to extend yeast replicative lifespan (SUPPLEMENT) - Foreign Subsite Supplement
    National Institute on Aging · 2023–2028· 2 renewals
    R01AG079883-03S1
  • Sub-PI
    Versatile platform for genome-wide R-loop mapping for aging and neurodegenerative disease research
    National Institute on Aging · 2024–2027 · via EpiCypher, Inc.
    R44AG090112-02
  • PI
    Novel pathways that regulate DNA double-strand break repair events in mammalian cells
    National Institute of General Medical Sciences · 2021–2027
    R35GM139816-05
Completed grants (11)
  • PI
    Chromatin's Role in Repair of Radiation-induced Damage
    National Cancer Institute · 2016–2025· 2 renewals
    R01CA095641-19
  • Sub-PI
    High-resolution genomic mapping of ssDNA binding proteins for Alzheimer's disease research
    National Institute on Aging · 2022–2023 · via EpiCypher, Inc.
    R43AG076049-01
  • PI
    2nd Biennial ASBMB - BSC Symposium on the Interplay between Epigenetic Regulation and Genome Integrity
    National Institute on Aging · 2022–2023
    R13AG079565-01
  • PI
    Addgene 704163
    Addgene, Inc. · 2022–2023
    Addgene 704163
  • PI
    Discovering the Molecular Mechanisms That Determine Replicative Lifespan
    National Institute on Aging · 2017–2022
    R01AG050660-04
  • PI
    The molecular mechanism of tumor suppression by PTEN via repression of satellite DNA (Cornell Seed Grant_Track 2)
    Cornell University · 2021–2021
    CU 211704-01
  • PI
    Chromatin Assembly Structure and Function
    National Institute of General Medical Sciences · 2016–2021· 2 renewals
    R01GM064475-14
  • Sub-PI
    Structural mechanisms of chromatin assembly
    National Institute of General Medical Sciences · 2020–2021 · via University of Colorado Denver
    R01GM135604-02
  • PI
    Genomic instability in the chromosomal context of physiological DNA double-strand break formation
    Starr Cancer Consortium · 2019–2020
    I12-0008
  • PI
    Disruption of protein synthesis by cytoplasmic inclusions of RNA-binding proteins drives cytotoxicity and neurodegeneration in ALS/FTD
    Weill Cornell Medical College · 2019–2020
    WCMC 200694-01
  • Sub-PI
    Structural and Functional Studies of the Histone Chaperone CAF-1
    National Institute of General Medical Sciences · 2016–2017 · via University of Colorado Denver Anschutz Medical Campus
    R01GM111902-03

Honors & distinctions

1 honor
  • Fellow · American Association for the Advancement of Science · 2017

News mentions

1 mentionView all WCM news ↗
  • Fighting Aging by Staying Compact
    November 25, 2024

    The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were elucidated in yeast, a model organism famous for making bread and beer and yet surprisingly similar to humans on the cellular level.

Mentoring

6 menteesAll publications with mentees →

External relationships

Advisory/Scientific Board Member

EpiCypher, Inc.

Professional Services

University of Alabama