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Highlights

  1. 1
    Nature communications · 2023
    PMID: 38097652PMCID: PMC10721928DOISenior author25 citations
  2. 2
    Angewandte Chemie (International ed. in English) · 2021
    PMID: 33433953PMCID: PMC8087158DOISenior author39 citations
  3. 3
    Cell chemical biology · 2023
    PMID: 37148884PMCID: PMC10240386DOISenior author19 citations

Publications

51 publications

Active

6 grants
  • PI
    Selective Plasmodium proteasome inhibitors as novel multi-stage antimalarials
    National Institute of Allergy and Infectious Diseases · 2019–2029· 2 renewals
    R01AI143714-08
  • PI
    Pharmacological Targeting of UBR5 for Breast Cancer Immunotherapy
    U.S. Department of Defense · 2026–2029
    HT9425-26-1-E178
  • PI
    Novel proteasome inhibitors targeting both beta5 and beta2 subunits for treatment of triple negative breast cancer
    National Cancer Institute · 2024–2028
    R01CA276053-03
  • PI
    Hijacking Plasmodium ubiquitin-proteasome system to defeat drug resistance
    National Institute of Allergy and Infectious Diseases · 2023–2028· 2 renewals
    R01AI177635-04
  • Co-I
    Targeted Degradation of Mycobacterial PknG for Host Control of Tuberculosis
    National Institute of Allergy and Infectious Diseases · 2025–2027
    R21AI185437-01A1
  • PI
    IpiNovyx Collaboration
    IpiNovyx Bio, Inc. · 2022–2026BioPharma Alliance
    IBI 227875-01
Completed grants (11)
  • Sub-PI
    Targeting the Plasmodium proteasome for prophylaxis and treatment of drug-resistant malaria in US Military personnel
    U.S. Department of Defense · 2022–2024 · via The Board of Trustees of the Leland Stanford Junior University
    W81XWH-22-1-0521
  • Co-I
    Investigating the proteasome of the malaria parasite Plasmodium falciparum
    The Brockman Foundation · 2019–2024
    BF 190027-01
  • PI
    Compounds that force Plasmodium falciparum to produce its own inhibitors
    National Institute of Allergy and Infectious Diseases · 2020–2023
    R21AI153485-02
  • PI
    Macrocyclic proteasome inhibitors for treatment of tuberculosis
    National Institute of Allergy and Infectious Diseases · 2020–2023
    R21AI144552-02
  • Sub-PI
    The Novel Role of the Immunoproteasome Subunit LMP7 in Allo-Immunity and T Cell Exhaustion
    National Institute of Allergy and Infectious Diseases · 2017–2022 · via The Brigham & Women's Hospital INC
    R01AI134842-05
  • PI
    Conversion of Novel and Orally Bioavailable Pathogens Proteasome Inhibitors to Human Proteasome Inhibitors
    Daedalus Fund for Innovation (Weill Cornell) · 2017–2021BioPharma Alliance
    DFI 180181-02
  • Co-I
    In Search of an Inhibitor of the E3 Ubiquitin Ligase UBR5 for Cancer Therapy
    Daedalus Fund for Innovation (Weill Cornell) · 2017–2020
    DF 180106-1
  • PI
    Novel Inhibitors of Malaria Proteasome
    National Institute of Allergy and Infectious Diseases · 2017–2020
    R21AI123794-02
  • KP
    ABLS IV LLC Research Collaboration Agreement
    Allied-Bristol Life Sciences · 2017–2019Contract
    BAA 183322-01
  • KP
    Biology of Lipoamide Dehydrogenase and 2-hydroxy-3-oxoadipate Synthase in Mtb
    National Institute of Allergy and Infectious Diseases · 2010–2017
    R01AI064768-07
  • PI
    Species Selective Dipeptide Inhibitors for Mtb Proteasome
    National Institute of Allergy and Infectious Diseases · 2013–2015
    R21AI101393-02EWO

Available technologies

News mentions

Media highlights

1 clip

Mentoring

3 mentees

External relationships

Ownership

IpiNovyx Bio, Inc.

Proprietary Interest

IpiNovyx Bio, Inc.

Other

IpiNovyx Bio, Inc.