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Overview

Dr. Christine M. Salvatore is an Associate Professor of Clinical Pediatrics in the Division of Pediatric Infectious Diseases at Weill Cornell Medical Center. She received her M.D. in Italy at the University of Trieste Faculty of Medicine and Surgery and completed her pediatric residency in Italy at Burlo Garofolo Children`s Hospital in Trieste (Italy). After working in Italy as an attending pediatrician, she came to the United States where she completed additional pediatric training at Jacobi Medical Center in New York City, and a fellowship in pediatric infectious disease at the University of Texas Southwestern Medical Center at Dallas. She is board certified in both Pediatrics and Pediatric Infectious Diseases.
 
Her interest in pediatric infectious diseases began in Italy, where she collaborated as Principal Site Investigator with the PENTA (Pediatric European Network for the Treatment of AIDS) and the Italian Register for HIV Infection in Children. Since then, Dr. Salvatore has been involved in several clinical trials, such as the effectiveness of antiretroviral drugs in HIV infected children, the role of antimicrobial lock therapy in clearing central venous catheter-related fungal and bacterial infections.
 
Clinical research is one of her main interests. While at UT Southwestern Medical Center at Dallas, she also conducted basic research studying, in a murine model, treatment strategies for Mycoplasma pneumoniae infections and the role of IL-12 in the pathogenesis of Mycoplasma pneumoniae respiratory infections.
 
Demonstrating her longstanding commitment to medical education, she has given lectures to medical students, residents and medical staff on general pediatrics, pediatric infectious diseases, pediatric HIV and infectious complications in pediatric solid organ transplantation

Highlights

  1. 1
    The Lancet. Child & adolescent health · 2020
    PMID: 32711687PMCID: PMC7377726DOIFirst author259 citations
  2. 2
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    PMID: 41764671PMCID: PMC12950654DOISenior author

Publications

40 publications

Active

3 grants
  • Sub-PI
    Pediatric Fungal Network STudy of Rare Invasive Fungal DisEases in Immunocompromised Pediatric Patients (PFN-STRIDE)
    National Institutes of Health · 2026–2027 · via Children's Hospital of Philadelphia
    U54AI198184-02
  • Sub-PI
    PROACTIVE NYS: Prospective Observational Study of Asymptomatic cCMV Transmission to Infants for Virological Evaluation in New York State
    Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2023–2026 · via Health Research INC (Center for Community Health)
    75N94021D00018
  • Sub-PI
    Short Course Versus Standard Course Antifungal Therapy for Pediatric Candidemia: A Multi-Center Randomized Controlled Trial
    National Institute of Allergy and Infectious Diseases · 2023–2026 · via Arkansas Children's Research Institute (ACRI)
    R01AI170385-01
Completed grants (4)
  • Sub-PI
    Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
    National Institute of Allergy and Infectious Diseases · 2019–2025 · via Arkansas Children's Research Institute (ACRI)· 2 renewals
    R01AI139032-05
  • Sub-PI
    A Randomized Trial to Determine the Role of Valganciclovir for Asymptomatic Cytomegalovirus Infected Hearing Impaired Infants
    National Inst on Deafness & Other Communication Disorders · 2019–2022 · via University of Utah
    U01DC014706-04
  • Sub-PI
    Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia
    Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2015–2020 · via Duke University
    R01HD081044-05
  • Sub-PI
    Multi-Center Studies to Improve Diagnosis and Treatment of Pediatric Candidiasis
    National Institute of Allergy and Infectious Diseases · 2014–2017 · via Duke University
    R01AI103315-03

Clinical research

8 studies

Active

4 studies
  • PI
    Short Course Versus Standard Course Antifungal Therapy for Uncomplicated Candidemia in Children and Adolescents: A Multi-Center Randomized Controlled Trial
    NA · University of Arkansas for Medical Sciences · OPEN TO ACCRUAL (as of 2025)
    Invasive Candidiasis
    NCT05763251
  • PI
    A Retrospective Study Of Infants Diagnosed With Congenital Cytomegalovirus
    Weill Medical College of Cornell University · OPEN TO ACCRUAL (as of 2025)
  • PI
    Prospective Observational Study of Asymptomatic cCMV Transmission to Infants for Virological Evaluation in New York State
    The Eunice Kennedy Shriver · OPEN TO ACCRUAL (as of 2024)
    Congenital CMV Infection; Sensorineural Hearing Loss
    NCT06226558
  • PI
    A PHASE 2A MULTICENTER, OBSERVER-BLINDED, RANDOMIZED 2 ARM STUDY TO INVESTIGATE PHARMACOKINETICS, SAFETY, TOLERABILITY AND EFFICACY OF INTRAVENOUS AZTREONAM-AVIBACTAM ± METRONIDAZOLE COMPARED TO BEST AVAILABLE THERAPY (BAT) IN PEDIATRIC PARTICIPANTS 9 MONTHS TO LESS THAN 18 YEARS OF AGE WITH SERIOUS GRAM-NEGATIVE BACTERIAL INFECTIONS INCLUDING COMPLICATED INTRA-ABDOMINAL INFECTION
    PHASE2 · Pfizer, Inc. · OPEN TO ACCRUAL (as of 2023)
    Gram-negative Bacterial Infections
    NCT05639647
Completed & closed trials (4)
  • PI
    Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
    National Institutes of Health · CLOSED TO ACCRUAL (as of 2024)
  • PI
    Perinatal COVID-19 Infection: An Observational Registry
    Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2024)
  • PI
    Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants: ValEAR Trial
    PHASE2 · University of Utah · IRB STUDY CLOSURE (as of 2023)
    Cmv Congenital; CMV; Congenital Cmv; SNHL; Sensorineural Hearing Loss
    NCT03107871
  • PI
    Pre-travel Counseling at NewYork-Presbyterian Hospital Ambulatory Care Pediatrics Practice
    Weill Medical College of Cornell University · IRB STUDY CLOSURE (as of 2020)

News mentions

  • In Brief: COVID-19 and Maternal and Newborn Health
    August 4, 2020

    Two studies from Weill Cornell Medicine and NewYork-Presbyterian investigators suggest that maternal-to-child transmission of SARS-CoV-2 is rare; however, one study found that complications after birth occurred for some mothers infected with the virus.