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Overview

Dr. Timothy R. Donahue is a nationally recognized surgical oncologist, pancreatic surgeon, surgeon-scientist, and academic leader with expertise in pancreatic and other gastrointestinal cancers and complex pancreatic surgery. As Chair of the Department of Surgery at Weill Cornell Medicine and Surgeon-in-Chief at NewYork-Presbyterian/Weill Cornell Medical Center, he leads a multidisciplinary department dedicated to providing exceptional surgical care while advancing scientific discovery and surgical education.

Dr. Donahue specializes in the surgical treatment of pancreatic and other gastrointestinal cancers, with particular expertise in pancreatic cancer and complex pancreatic surgery. His approach emphasizes multidisciplinary care, bringing together surgeons, medical oncologists, gastroenterologists, radiation oncologists, radiologists, pathologists, and other specialists to develop an individualized treatment plan for each patient. His clinical practice is closely integrated with research and clinical trials, providing patients access to promising new therapies and treatment approaches.

As a surgeon-scientist, Dr. Donahue’s research focuses on understanding the interaction between pancreatic cancer and the immune system and developing new strategies to overcome treatment resistance. His laboratory and translational research programs seek to move discoveries from the laboratory into clinical trials and, ultimately, improve outcomes for patients with pancreatic cancer.

Highlights

  1. 1
    Proceedings of the National Academy of Sciences of the United States of America · 2021
    PMID: 33597293PMCID: PMC7923374DOISenior author35 citations
  2. 2
    Surgery · 2020
    PMID: 31992444DOISenior author46 citations
  3. 3
    Annals of surgical oncology · 2026
    PMID: 41538116PMCID: PMC13083458DOISenior author4 citations

Publications

92 publications

Active

4 grants
  • PI
    UCLA Surgeon-Scientist Basic Cancer Research Training Program (UCLA Surgeon-Scientist BCRTP)
    NCI · 2025–2030 · via NIH RePORTER
    T32CA302559-01
  • PI
    Causes and Consequences of Adenosine Signaling in Pancreatic Cancer
    NCI · 2024–2029 · via NIH RePORTER
    R01CA290888-03
  • PI
    Targeting KRAS and adenosine mediated immunosuppression in pancreatic cancer
    NCI · 2021–2026 · via NIH RePORTER
    R01CA260678-05
  • PI
    Leveraging Vulnerabilities Induced by STING Activation in Pancreatic Cancer
    NCI · 2021–2026 · via NIH RePORTER
    R01CA250529-05
Completed grants (2)
  • PI
    UCLA Multifunctional Mesoporous Silica Nanoparticle Platform for Treatment of Pancreas Cancer
    NCI · 2015–2021 · via NIH RePORTER
    U01CA198846-05
  • PI
    PET Imaging-guided Personalized Therapy in Pancreatic Cancer
    NCI · 2014–2020 · via NIH RePORTER
    R01CA187678-05

Media highlights

4 clips

External relationships

Leadership Roles

Trethera Corp

Ownership

Trethera Corp

Advisory/Scientific Board Member

RenovoRx, Inc.

Professional Services

The Regents of the University of California, Los Angeles